Perfluoroalkyl Substances in Arctic Polar Bear and Ringed Seal From East Greenland and Hudson Bay: Comparisons of Adipose and Liver Levels and Patterns, and In Vitro Depletion and Metabolite Formation of PFAS Precursors
The levels of 22 perfluorinated alkyl substances (PFASs) were examined in the livers of polar bears (PB) from Southern Hudson Bay (SHB) and Western Hudson Bay (WHB) and in the livers and adipose tissues of East Greenland (EG) PB and ringed seals (RS), all harvested in recent years. EG PB livers cont...
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ftcarletonuniv:oai:curve.carleton.ca:26305 2023-05-15T14:55:05+02:00 Perfluoroalkyl Substances in Arctic Polar Bear and Ringed Seal From East Greenland and Hudson Bay: Comparisons of Adipose and Liver Levels and Patterns, and In Vitro Depletion and Metabolite Formation of PFAS Precursors Boisvert, Gabriel 2016 https://curve.carleton.ca/35241377-47fe-45c3-a402-fed5e51b7cd7 http://catalogue.library.carleton.ca/record=b3942841 https://doi.org/10.22215/etd/2016-11586 unknown https://curve.carleton.ca/35241377-47fe-45c3-a402-fed5e51b7cd7 http://catalogue.library.carleton.ca/record=b3942841 https://doi.org/10.22215/etd/2016-11586 Thesis/Dissertation 2016 ftcarletonuniv https://doi.org/10.22215/etd/2016-11586 2022-01-23T08:17:28Z The levels of 22 perfluorinated alkyl substances (PFASs) were examined in the livers of polar bears (PB) from Southern Hudson Bay (SHB) and Western Hudson Bay (WHB) and in the livers and adipose tissues of East Greenland (EG) PB and ringed seals (RS), all harvested in recent years. EG PB livers contained greater concentrations of ΣPFAS than SHB and WHB bears, while having greater proportions of perfluorooctane sulfonic acid (PFOS). ΣPFAS concentrations in EG PB were greater than in RS both in liver and in adipose, while no PFOS was detected in RS blubber. The biotransformation of N-Ethyl-perfluorooctane sulfonamide was significant for high enzymatic activity PB, while FOSA formation was not significant for low enzymatic activity RS. This thesis underlined the necessity to study the fate of PFASs in the Arctic marine foodweb, and the importance of short-chained PFASs and precursors when establishing PFAS exposure and levels. Thesis Arctic East Greenland Greenland Hudson Bay ringed seal CURVE - Carleton University Research Virtual Environment Arctic Hudson Bay Greenland Hudson |
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Open Polar |
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CURVE - Carleton University Research Virtual Environment |
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ftcarletonuniv |
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unknown |
description |
The levels of 22 perfluorinated alkyl substances (PFASs) were examined in the livers of polar bears (PB) from Southern Hudson Bay (SHB) and Western Hudson Bay (WHB) and in the livers and adipose tissues of East Greenland (EG) PB and ringed seals (RS), all harvested in recent years. EG PB livers contained greater concentrations of ΣPFAS than SHB and WHB bears, while having greater proportions of perfluorooctane sulfonic acid (PFOS). ΣPFAS concentrations in EG PB were greater than in RS both in liver and in adipose, while no PFOS was detected in RS blubber. The biotransformation of N-Ethyl-perfluorooctane sulfonamide was significant for high enzymatic activity PB, while FOSA formation was not significant for low enzymatic activity RS. This thesis underlined the necessity to study the fate of PFASs in the Arctic marine foodweb, and the importance of short-chained PFASs and precursors when establishing PFAS exposure and levels. |
format |
Thesis |
author |
Boisvert, Gabriel |
spellingShingle |
Boisvert, Gabriel Perfluoroalkyl Substances in Arctic Polar Bear and Ringed Seal From East Greenland and Hudson Bay: Comparisons of Adipose and Liver Levels and Patterns, and In Vitro Depletion and Metabolite Formation of PFAS Precursors |
author_facet |
Boisvert, Gabriel |
author_sort |
Boisvert, Gabriel |
title |
Perfluoroalkyl Substances in Arctic Polar Bear and Ringed Seal From East Greenland and Hudson Bay: Comparisons of Adipose and Liver Levels and Patterns, and In Vitro Depletion and Metabolite Formation of PFAS Precursors |
title_short |
Perfluoroalkyl Substances in Arctic Polar Bear and Ringed Seal From East Greenland and Hudson Bay: Comparisons of Adipose and Liver Levels and Patterns, and In Vitro Depletion and Metabolite Formation of PFAS Precursors |
title_full |
Perfluoroalkyl Substances in Arctic Polar Bear and Ringed Seal From East Greenland and Hudson Bay: Comparisons of Adipose and Liver Levels and Patterns, and In Vitro Depletion and Metabolite Formation of PFAS Precursors |
title_fullStr |
Perfluoroalkyl Substances in Arctic Polar Bear and Ringed Seal From East Greenland and Hudson Bay: Comparisons of Adipose and Liver Levels and Patterns, and In Vitro Depletion and Metabolite Formation of PFAS Precursors |
title_full_unstemmed |
Perfluoroalkyl Substances in Arctic Polar Bear and Ringed Seal From East Greenland and Hudson Bay: Comparisons of Adipose and Liver Levels and Patterns, and In Vitro Depletion and Metabolite Formation of PFAS Precursors |
title_sort |
perfluoroalkyl substances in arctic polar bear and ringed seal from east greenland and hudson bay: comparisons of adipose and liver levels and patterns, and in vitro depletion and metabolite formation of pfas precursors |
publishDate |
2016 |
url |
https://curve.carleton.ca/35241377-47fe-45c3-a402-fed5e51b7cd7 http://catalogue.library.carleton.ca/record=b3942841 https://doi.org/10.22215/etd/2016-11586 |
geographic |
Arctic Hudson Bay Greenland Hudson |
geographic_facet |
Arctic Hudson Bay Greenland Hudson |
genre |
Arctic East Greenland Greenland Hudson Bay ringed seal |
genre_facet |
Arctic East Greenland Greenland Hudson Bay ringed seal |
op_relation |
https://curve.carleton.ca/35241377-47fe-45c3-a402-fed5e51b7cd7 http://catalogue.library.carleton.ca/record=b3942841 https://doi.org/10.22215/etd/2016-11586 |
op_doi |
https://doi.org/10.22215/etd/2016-11586 |
_version_ |
1766326875332804608 |