Epidemiology of gestational diabetes mellitus and infant macrosomia among the Cree of James Bay
The objectives of this research were to determine the prevalence of gestational diabetes mellitus (GDM) among the Cree of James Bay, identify independent risk factors for GDM and infant macrosomia in this population and compare the risk for GDM and infant macrosomia among Cree women with Canadian no...
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1999
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ftcanadathes:oai:collectionscanada.gc.ca:QMM.35934 2023-05-15T15:59:24+02:00 Epidemiology of gestational diabetes mellitus and infant macrosomia among the Cree of James Bay Rodrigues, Shaila. Gray-Donald, Katherine (advisor) Doctor of Philosophy (School of Dietetics and Human Nutrition.) 1999 application/pdf http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35934 en eng McGill University alephsysno: 001657411 proquestno: NQ50248 Theses scanned by UMI/ProQuest. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35934 All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. Fetal Macrosomia -- Quebec Diabetes in pregnancy -- James Bay Region -- Epidemiology Birth weight -- James Bay Region Cree Indians -- James Bay Region Electronic Thesis or Dissertation 1999 ftcanadathes 2014-02-16T00:44:36Z The objectives of this research were to determine the prevalence of gestational diabetes mellitus (GDM) among the Cree of James Bay, identify independent risk factors for GDM and infant macrosomia in this population and compare the risk for GDM and infant macrosomia among Cree women with Canadian non-Native women. The prevalence of GDM using the National Diabetes Data Group criteria among the Cree was 12.8% (95% CI: 10.1--15.5), among the highest ever reported for an Aboriginal group. Independent risk factors for GDM among the Cree were advanced age, pregravid overweight and previous GDM. A comparison of risk of GDM between Cree and non-Native women revealed a significant interaction between ethnicity and pregravid weight. Overweight Cree women were at an elevated risk for GDM compared with overweight non-Native women (OR: 2.3, 95% CI: 1.3--3.8), whereas the risk for GDM was not statistically different between normal weight Cree and non-Native women (OR: 1.4, 95% CI: 0.7--2.7) after adjusting for age, parity, and smoking status. Mean birth weight among Cree infants was 3859 +/- 519 g, the highest reported for any ethnic group in the world. Macrosomia prevalence was also high at 34.3%. Independent risk factors for macrosomia among the Cree were advanced age, pregravid overweight and GDM. A significant interaction was noted between ethnicity and GDM on risk for macrosomia. GDM increased the risk for macrosomia 4.5-fold among the Cree but had no significant effect among non-Natives. After adjusting for age, parity, pregravid weight, gestational weight gain, GDM, gestational duration and smoking status, Cree infants remained heavier than non-Native infants by 235 g. The results of this research indicate the need to control pregravid obesity through culturally acceptable dietary modifications and exercise in order to minimize the risk for GDM among Cree women. The significant impact of GDM on risk for macrosomia among the Cree calls for the re-evaluation of the existi Thesis Cree indians James Bay Theses Canada/Thèses Canada (Library and Archives Canada) |
institution |
Open Polar |
collection |
Theses Canada/Thèses Canada (Library and Archives Canada) |
op_collection_id |
ftcanadathes |
language |
English |
topic |
Fetal Macrosomia -- Quebec Diabetes in pregnancy -- James Bay Region -- Epidemiology Birth weight -- James Bay Region Cree Indians -- James Bay Region |
spellingShingle |
Fetal Macrosomia -- Quebec Diabetes in pregnancy -- James Bay Region -- Epidemiology Birth weight -- James Bay Region Cree Indians -- James Bay Region Rodrigues, Shaila. Epidemiology of gestational diabetes mellitus and infant macrosomia among the Cree of James Bay |
topic_facet |
Fetal Macrosomia -- Quebec Diabetes in pregnancy -- James Bay Region -- Epidemiology Birth weight -- James Bay Region Cree Indians -- James Bay Region |
description |
The objectives of this research were to determine the prevalence of gestational diabetes mellitus (GDM) among the Cree of James Bay, identify independent risk factors for GDM and infant macrosomia in this population and compare the risk for GDM and infant macrosomia among Cree women with Canadian non-Native women. The prevalence of GDM using the National Diabetes Data Group criteria among the Cree was 12.8% (95% CI: 10.1--15.5), among the highest ever reported for an Aboriginal group. Independent risk factors for GDM among the Cree were advanced age, pregravid overweight and previous GDM. A comparison of risk of GDM between Cree and non-Native women revealed a significant interaction between ethnicity and pregravid weight. Overweight Cree women were at an elevated risk for GDM compared with overweight non-Native women (OR: 2.3, 95% CI: 1.3--3.8), whereas the risk for GDM was not statistically different between normal weight Cree and non-Native women (OR: 1.4, 95% CI: 0.7--2.7) after adjusting for age, parity, and smoking status. Mean birth weight among Cree infants was 3859 +/- 519 g, the highest reported for any ethnic group in the world. Macrosomia prevalence was also high at 34.3%. Independent risk factors for macrosomia among the Cree were advanced age, pregravid overweight and GDM. A significant interaction was noted between ethnicity and GDM on risk for macrosomia. GDM increased the risk for macrosomia 4.5-fold among the Cree but had no significant effect among non-Natives. After adjusting for age, parity, pregravid weight, gestational weight gain, GDM, gestational duration and smoking status, Cree infants remained heavier than non-Native infants by 235 g. The results of this research indicate the need to control pregravid obesity through culturally acceptable dietary modifications and exercise in order to minimize the risk for GDM among Cree women. The significant impact of GDM on risk for macrosomia among the Cree calls for the re-evaluation of the existi |
author2 |
Gray-Donald, Katherine (advisor) |
format |
Thesis |
author |
Rodrigues, Shaila. |
author_facet |
Rodrigues, Shaila. |
author_sort |
Rodrigues, Shaila. |
title |
Epidemiology of gestational diabetes mellitus and infant macrosomia among the Cree of James Bay |
title_short |
Epidemiology of gestational diabetes mellitus and infant macrosomia among the Cree of James Bay |
title_full |
Epidemiology of gestational diabetes mellitus and infant macrosomia among the Cree of James Bay |
title_fullStr |
Epidemiology of gestational diabetes mellitus and infant macrosomia among the Cree of James Bay |
title_full_unstemmed |
Epidemiology of gestational diabetes mellitus and infant macrosomia among the Cree of James Bay |
title_sort |
epidemiology of gestational diabetes mellitus and infant macrosomia among the cree of james bay |
publisher |
McGill University |
publishDate |
1999 |
url |
http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35934 |
op_coverage |
Doctor of Philosophy (School of Dietetics and Human Nutrition.) |
genre |
Cree indians James Bay |
genre_facet |
Cree indians James Bay |
op_relation |
alephsysno: 001657411 proquestno: NQ50248 Theses scanned by UMI/ProQuest. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35934 |
op_rights |
All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
_version_ |
1766395360982335488 |