Apnea Stimulates the Adaptive Response to Oxidative Stress in Elephant Seal Pups

• Main Authors: José Pablo Vázquez-Medina, Tania Zenteno-Savín, Michael S. Tift, Henry Jay Forman, Daniel E. Crocker, Rudy M. Ortiz
• Format: Article in Journal/Newspaper
• Language: English
• Published: Journal of Experimental Biology 2011
• Subjects: apnea; antioxidant; reperfusion; hypoxemia; elephant seal; ischemia; oxidative stress; Medina; Pablo; Elephant Seal
• Online Access: http://hdl.handle.net/10211.3/118183

Extended breath-hold (apnea) bouts are routine during diving and sleeping in seals. These apneas result in oxygen store depletion and blood flow redistribution towards obligatory oxygen-dependent tissues, exposing seals to critical levels of ischemia and hypoxemia. The subsequent reperfusion/reoxyge...