Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle
The objectives of this study were to estimate variance components and identify regions of the genome associated with traits related to embryo transfer in Holsteins. Reproductive technologies are used in the dairy industry to increase the reproductive rate of superior females. A drawback of these met...
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Online Access: | http://hdl.handle.net/11452/30134 https://doi.org/10.3168/jds.2016-11907 https://www.sciencedirect.com/science/article/pii/S0022030217300735 |
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ftbursauludaguni:oai:localhost:11452/30134 2023-05-15T15:44:48+02:00 Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle Gaddis, Kristen L. Parker Null, Daniel J. Cole, John Bruce Hansen, Peter James Uludağ Üniversitesi/Veteriner Fakültesi/Hayvan Bilimleri Anabilim Dalı. orcid:0000-0002-5611-4993 Dikmen, Serdal A-5731-2018 8280302600 2016-11-21 application/pdf http://hdl.handle.net/11452/30134 https://doi.org/10.3168/jds.2016-11907 https://www.sciencedirect.com/science/article/pii/S0022030217300735 en eng Elsevier Makale - Uluslararası Hakemli Dergi Journal of Dairy Science Yurt dışı Sanayi Gaddis, K. L. P. vd. (2017). ''Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle''. Journal of Dairy Science, 100(4), 2877-2891. 0022-0302 https://doi.org/10.3168/jds.2016-11907 https://www.sciencedirect.com/science/article/pii/S0022030217300735 1525-3198 http://hdl.handle.net/11452/30134 000396643300039 2-s2.0-85010628682 2877 2891 100 4 28131573 info:eu-repo/semantics/openAccess Atıf Gayri Ticari Türetilemez 4.0 Uluslararası http://creativecommons.org/licenses/by-nc-nd/4.0/ CC-BY-NC-ND Agriculture Food science & technology Embryo transfer Genetic parameter In vitro fertilization Superovulation Signaling pathway Ovulation rate Parameters Genome Growth Fertility Estradiol Schemes Program Success Animals Cattle Female Fertilization in vitro Oocytes Reproduction dairy & animal science Embryo Bison Bison Athabascae Blastocyst Animal Bovine Oocyte Veterinary Article 2016 ftbursauludaguni https://doi.org/10.3168/jds.2016-11907 2023-01-05T17:51:04Z The objectives of this study were to estimate variance components and identify regions of the genome associated with traits related to embryo transfer in Holsteins. Reproductive technologies are used in the dairy industry to increase the reproductive rate of superior females. A drawback of these methods remains the variability of animal responses to the procedures. If some variability can be explained genetically, selection can be used to improve animal response. Data collected from a Holstein dairy farm in Florida from 2008 to 2015 included 926 superovulation records (number of structures recovered and number of good embryos), 628 in vitro fertilization records (number of oocytes collected, number of cleaved embryos, number of high-and low-quality embryos, and number of transferrable embryos), and 12,089 embryo transfer records (pregnancy success). Two methods of transformation (logarithmic and Anscombe) were applied to count variables and results were compared. Univariate animal models were fitted for each trait with the exception of pregnancy success after embryo transfer. Due to the binary nature of the latter trait, a threshold liability model was fitted that accounted for the genetic effect of both the recipient and the embryo. Both transformation methods produced similar results. Single-step genomic BLUP analyses were performed and SNP effects estimated for traits with a significant genetic component. Heritability of number of structures recovered and number of good embryos when log-transformed were 0.27 +/- 0.08 and 0.15 +/- 0.07, respectively. Heritability estimates from the in vitro fertilization data ranged from 0.01 +/- 0.08 to 0.21 +/- 0.15, but were not significantly different from zero. Recipient and embryo heritability (standard deviation) of pregnancy success after embryo transfer was 0.03 (0.01) and 0.02 (0.01), respectively. The 10-SNP window explaining the largest proportion of variance (0.37%) for total structures collected was located on chromosome 8 beginning at 55,663,248 bp. Similar ... Article in Journal/Newspaper Bison bison athabascae Açık Erişim@BUU (Bursa Uludağ Üniversitesi) Journal of Dairy Science 100 4 2877 2891 |
institution |
Open Polar |
collection |
Açık Erişim@BUU (Bursa Uludağ Üniversitesi) |
op_collection_id |
ftbursauludaguni |
language |
English |
topic |
Agriculture Food science & technology Embryo transfer Genetic parameter In vitro fertilization Superovulation Signaling pathway Ovulation rate Parameters Genome Growth Fertility Estradiol Schemes Program Success Animals Cattle Female Fertilization in vitro Oocytes Reproduction dairy & animal science Embryo Bison Bison Athabascae Blastocyst Animal Bovine Oocyte Veterinary |
spellingShingle |
Agriculture Food science & technology Embryo transfer Genetic parameter In vitro fertilization Superovulation Signaling pathway Ovulation rate Parameters Genome Growth Fertility Estradiol Schemes Program Success Animals Cattle Female Fertilization in vitro Oocytes Reproduction dairy & animal science Embryo Bison Bison Athabascae Blastocyst Animal Bovine Oocyte Veterinary Gaddis, Kristen L. Parker Null, Daniel J. Cole, John Bruce Hansen, Peter James Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle |
topic_facet |
Agriculture Food science & technology Embryo transfer Genetic parameter In vitro fertilization Superovulation Signaling pathway Ovulation rate Parameters Genome Growth Fertility Estradiol Schemes Program Success Animals Cattle Female Fertilization in vitro Oocytes Reproduction dairy & animal science Embryo Bison Bison Athabascae Blastocyst Animal Bovine Oocyte Veterinary |
description |
The objectives of this study were to estimate variance components and identify regions of the genome associated with traits related to embryo transfer in Holsteins. Reproductive technologies are used in the dairy industry to increase the reproductive rate of superior females. A drawback of these methods remains the variability of animal responses to the procedures. If some variability can be explained genetically, selection can be used to improve animal response. Data collected from a Holstein dairy farm in Florida from 2008 to 2015 included 926 superovulation records (number of structures recovered and number of good embryos), 628 in vitro fertilization records (number of oocytes collected, number of cleaved embryos, number of high-and low-quality embryos, and number of transferrable embryos), and 12,089 embryo transfer records (pregnancy success). Two methods of transformation (logarithmic and Anscombe) were applied to count variables and results were compared. Univariate animal models were fitted for each trait with the exception of pregnancy success after embryo transfer. Due to the binary nature of the latter trait, a threshold liability model was fitted that accounted for the genetic effect of both the recipient and the embryo. Both transformation methods produced similar results. Single-step genomic BLUP analyses were performed and SNP effects estimated for traits with a significant genetic component. Heritability of number of structures recovered and number of good embryos when log-transformed were 0.27 +/- 0.08 and 0.15 +/- 0.07, respectively. Heritability estimates from the in vitro fertilization data ranged from 0.01 +/- 0.08 to 0.21 +/- 0.15, but were not significantly different from zero. Recipient and embryo heritability (standard deviation) of pregnancy success after embryo transfer was 0.03 (0.01) and 0.02 (0.01), respectively. The 10-SNP window explaining the largest proportion of variance (0.37%) for total structures collected was located on chromosome 8 beginning at 55,663,248 bp. Similar ... |
author2 |
Uludağ Üniversitesi/Veteriner Fakültesi/Hayvan Bilimleri Anabilim Dalı. orcid:0000-0002-5611-4993 Dikmen, Serdal A-5731-2018 8280302600 |
format |
Article in Journal/Newspaper |
author |
Gaddis, Kristen L. Parker Null, Daniel J. Cole, John Bruce Hansen, Peter James |
author_facet |
Gaddis, Kristen L. Parker Null, Daniel J. Cole, John Bruce Hansen, Peter James |
author_sort |
Gaddis, Kristen L. Parker |
title |
Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle |
title_short |
Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle |
title_full |
Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle |
title_fullStr |
Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle |
title_full_unstemmed |
Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle |
title_sort |
evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in holstein cattle |
publisher |
Elsevier |
publishDate |
2016 |
url |
http://hdl.handle.net/11452/30134 https://doi.org/10.3168/jds.2016-11907 https://www.sciencedirect.com/science/article/pii/S0022030217300735 |
genre |
Bison bison athabascae |
genre_facet |
Bison bison athabascae |
op_relation |
Makale - Uluslararası Hakemli Dergi Journal of Dairy Science Yurt dışı Sanayi Gaddis, K. L. P. vd. (2017). ''Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle''. Journal of Dairy Science, 100(4), 2877-2891. 0022-0302 https://doi.org/10.3168/jds.2016-11907 https://www.sciencedirect.com/science/article/pii/S0022030217300735 1525-3198 http://hdl.handle.net/11452/30134 000396643300039 2-s2.0-85010628682 2877 2891 100 4 28131573 |
op_rights |
info:eu-repo/semantics/openAccess Atıf Gayri Ticari Türetilemez 4.0 Uluslararası http://creativecommons.org/licenses/by-nc-nd/4.0/ |
op_rightsnorm |
CC-BY-NC-ND |
op_doi |
https://doi.org/10.3168/jds.2016-11907 |
container_title |
Journal of Dairy Science |
container_volume |
100 |
container_issue |
4 |
container_start_page |
2877 |
op_container_end_page |
2891 |
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1766379164701556736 |