Chemoenzymatic synthesis of both enantiomers of 2-chloro-1-(2-furyl)ethanol

Enzyme catalyzed transesterification of rac-2-chloro-1-(2-furyl)ethanol rac-1 using vinyl acetate afforded the enantiomers of 2-chloro-1-(2-furyl) ethanol 1 and 2-chloro-1-(2-furyl)ethyl acetate 2 in high enantiomeric excess. Several lipases were used for the kinetic resolution of racemic 2-chloro-1...

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Main Authors: Gercek Z., Karakaya D., Demir A.S.
Other Authors: Zonguldak Bülent Ecevit Üniversitesi
Format: Article in Journal/Newspaper
Language:English
Published: 2005
Subjects:
Antarc*
Antarctica
Online Access:https://hdl.handle.net/20.500.12628/4651
https://doi.org/10.1016/j.tetasy.2005.04.007
id ftbuelentecevitu:oai:acikarsiv.beun.edu.tr:20.500.12628/4651
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spelling ftbuelentecevitu:oai:acikarsiv.beun.edu.tr:20.500.12628/4651 2023-05-15T13:50:38+02:00 Chemoenzymatic synthesis of both enantiomers of 2-chloro-1-(2-furyl)ethanol Gercek Z. Karakaya D. Demir A.S. Zonguldak Bülent Ecevit Üniversitesi 2005 https://hdl.handle.net/20.500.12628/4651 https://doi.org/10.1016/j.tetasy.2005.04.007 eng eng 10.1016/j.tetasy.2005.04.007 Tetrahedron Asymmetry Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı 0957-4166 https://dx.doi.org/10.1016/j.tetasy.2005.04.007 https://hdl.handle.net/20.500.12628/4651 16 10 1743 1746 info:eu-repo/semantics/closedAccess article 2005 ftbuelentecevitu https://doi.org/20.500.12628/4651 https://doi.org/10.1016/j.tetasy.2005.04.007 2023-01-15T16:42:13Z Enzyme catalyzed transesterification of rac-2-chloro-1-(2-furyl)ethanol rac-1 using vinyl acetate afforded the enantiomers of 2-chloro-1-(2-furyl) ethanol 1 and 2-chloro-1-(2-furyl)ethyl acetate 2 in high enantiomeric excess. Several lipases were used for the kinetic resolution of racemic 2-chloro-1-(2-furyl)ethanol l, in which the lipases from Pseudomonas cepacia, Candida antarctica and Candida cylindracea displayed high enantioselectivity towards 1. © 2005 Elsevier Ltd. All rights reserved. Türkiye Bilimler Akademisi National Council for Scientific Research Financial support from the Scientific and Technical Research Council of Turkey (TUBITAK), the Turkish Academy of Sciences (TÜBA), the Turkish State Planning Organization (for LC–MS and HPLC), the Middle East Technical University (DOSAP) and Zonguldak Karaelmas University is gratefully acknowledged. Article in Journal/Newspaper Antarc* Antarctica DSpace@BEÜ - Zonguldak Bülent Ecevit University Institutional Repository
institution Open Polar
collection DSpace@BEÜ - Zonguldak Bülent Ecevit University Institutional Repository
op_collection_id ftbuelentecevitu
language English
description Enzyme catalyzed transesterification of rac-2-chloro-1-(2-furyl)ethanol rac-1 using vinyl acetate afforded the enantiomers of 2-chloro-1-(2-furyl) ethanol 1 and 2-chloro-1-(2-furyl)ethyl acetate 2 in high enantiomeric excess. Several lipases were used for the kinetic resolution of racemic 2-chloro-1-(2-furyl)ethanol l, in which the lipases from Pseudomonas cepacia, Candida antarctica and Candida cylindracea displayed high enantioselectivity towards 1. © 2005 Elsevier Ltd. All rights reserved. Türkiye Bilimler Akademisi National Council for Scientific Research Financial support from the Scientific and Technical Research Council of Turkey (TUBITAK), the Turkish Academy of Sciences (TÜBA), the Turkish State Planning Organization (for LC–MS and HPLC), the Middle East Technical University (DOSAP) and Zonguldak Karaelmas University is gratefully acknowledged.
author2 Zonguldak Bülent Ecevit Üniversitesi
format Article in Journal/Newspaper
author Gercek Z.
Karakaya D.
Demir A.S.
spellingShingle Gercek Z.
Karakaya D.
Demir A.S.
Chemoenzymatic synthesis of both enantiomers of 2-chloro-1-(2-furyl)ethanol
author_facet Gercek Z.
Karakaya D.
Demir A.S.
author_sort Gercek Z.
title Chemoenzymatic synthesis of both enantiomers of 2-chloro-1-(2-furyl)ethanol
title_short Chemoenzymatic synthesis of both enantiomers of 2-chloro-1-(2-furyl)ethanol
title_full Chemoenzymatic synthesis of both enantiomers of 2-chloro-1-(2-furyl)ethanol
title_fullStr Chemoenzymatic synthesis of both enantiomers of 2-chloro-1-(2-furyl)ethanol
title_full_unstemmed Chemoenzymatic synthesis of both enantiomers of 2-chloro-1-(2-furyl)ethanol
title_sort chemoenzymatic synthesis of both enantiomers of 2-chloro-1-(2-furyl)ethanol
publishDate 2005
url https://hdl.handle.net/20.500.12628/4651
https://doi.org/10.1016/j.tetasy.2005.04.007
genre Antarc*
Antarctica
genre_facet Antarc*
Antarctica
op_relation 10.1016/j.tetasy.2005.04.007
Tetrahedron Asymmetry
Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
0957-4166
https://dx.doi.org/10.1016/j.tetasy.2005.04.007
https://hdl.handle.net/20.500.12628/4651
16
10
1743
1746
op_rights info:eu-repo/semantics/closedAccess
op_doi https://doi.org/20.500.12628/4651
https://doi.org/10.1016/j.tetasy.2005.04.007
_version_ 1766253789385326592

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