Claudin interaction changes during saltwater acclimation in Salmo-salar

• Main Authors: Hutchins, Joshua, Wong, Kevin, Lundquist, Thomas, Mizrachi, Dario
• Format: Text
• Language: English
• Published: BYU ScholarsArchive 2023
• Subjects: Claudins; Paracellular Transport; Transport Proteins; Metabolism; Ecoli;/; Biophysics; Life Sciences; Atlantic salmon; Salmo salar
• Online Access: https://scholarsarchive.byu.edu/library_studentposters_2023/61; https://scholarsarchive.byu.edu/context/library_studentposters_2023/article/1006/type/native/viewcontent/Claudin_interaction_changes_during_saltwater_acclimation.mp4

3rd Place Video Claudins, a protein family found in tight junctions that contribute to membrane permeability, are proven to be expressed at varying levels in Salmo Salar (Atlantic Salmon) depending on the concentration of salt in the water. It has been proven that there is an increase in expression of claudin 3 and 10 in the kidneys, liver, heart, intestine, and brain as the salmon acclimate to ocean water. We proposed that this upregulation of claudins 3 and ten is due to the need for stronger claudin interactions for decreased membrane permeability in the salt saturated water, and that the methods used in this experiment are valid to test the strength of claudin—claudin interactions. https://scholarsarchive.byu.edu/library_studentposters_2023/1006/thumbnail.jpg