ORCA project for Taylor Turnbull

• Main Author: Turnbull, Taylor
• Format: Text
• Language: unknown
• Published: BYU ScholarsArchive 2014
• Subjects: serum proteomics profiles; Alzheimer's disease; AD; Biology; Orca
• Online Access: https://scholarsarchive.byu.edu/jur/vol2014/iss1/740; https://scholarsarchive.byu.edu/context/jur/article/3079/viewcontent/auto_convert.pdf

Our project went according to plan, with a few small modifications along the way. Initially, we had proposed to incorporate gender profiling in attempt to understand the differences in serum proteomics profiles in men and women. As planned the information concerning gender was obtained and used to effectively design an additional project, to analyze serum differences between Alzheimer’s and non-Alzheimer’s individuals. Utilizing the novel capillary liquid chromatography method outlined in our proposal we were able to analyze our serum samples. By comparing the resulting mass spectra using specialized statistical methods we have been able to identify several biomarkers. The information we have found and are still finding will provide us with important information about the presence of proteomics profiles. So far the results are turning of the information that we’d hoped and hypothesized we’d find.