Missed, not missing: Phylogenomic evidence for the existence of Avian FoxP3

• Published in: PLOS ONE
• Main Authors: Denyer, Michael P., Pinheiro, D.Y., Garden, O.A., Shepherd, Adrian J.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science 2016
• Subjects: Biological Sciences; Parus; Falco peregrinus; peregrine falcon
• Online Access: https://eprints.bbk.ac.uk/id/eprint/14635/; https://eprints.bbk.ac.uk/id/eprint/14635/1/14635.PDF; https://doi.org/10.1371/journal.pone.0150988

The Forkhead box transcription factor FoxP3 is pivotal to the development and function of regulatory T cells (Tregs), which make a major contribution to peripheral tolerance. FoxP3 is believed to perform a regulatory role in all the vertebrate species in which it has been detected. The prevailing vi...