THE EFFECTS OF TWO DOSAGES OF MIDAZOLAM ON SHORT-DURATION ANESTHESIA IN THE HARP SEAL (PHOCA GROENLANDICA)
The purpose of this study was to provide safe anesthesia for bronchoalveolar lavage and assess the utility of premedication with i.m. midazolam for short-duration anesthesia with isoflurane in harp seals (Phoca groenlandica). Fourteen yearling harp seal pups were anesthetized three times each as par...
Published in: | Journal of Zoo and Wildlife Medicine |
---|---|
Main Authors: | , , , |
Format: | Text |
Language: | English |
Published: |
American Association of Zoo Veterinarians
2006
|
Subjects: | |
Online Access: | https://doi.org/10.1638/05-052.1 |
id |
ftbioone:10.1638/05-052.1 |
---|---|
record_format |
openpolar |
spelling |
ftbioone:10.1638/05-052.1 2023-07-30T04:04:00+02:00 THE EFFECTS OF TWO DOSAGES OF MIDAZOLAM ON SHORT-DURATION ANESTHESIA IN THE HARP SEAL (PHOCA GROENLANDICA) Daniel S. J. Pang Yves Rondenay Lena Measures Stéphane Lair Daniel S. J. Pang Yves Rondenay Lena Measures Stéphane Lair world 2006-03-01 text/HTML https://doi.org/10.1638/05-052.1 en eng American Association of Zoo Veterinarians doi:10.1638/05-052.1 All rights reserved. https://doi.org/10.1638/05-052.1 Text 2006 ftbioone https://doi.org/10.1638/05-052.1 2023-07-09T10:45:03Z The purpose of this study was to provide safe anesthesia for bronchoalveolar lavage and assess the utility of premedication with i.m. midazolam for short-duration anesthesia with isoflurane in harp seals (Phoca groenlandica). Fourteen yearling harp seal pups were anesthetized three times each as part of a prospective, cross-over, blinded study. Each animal received i.m. premedication with saline, low-dose, or high-dose midazolam (respectively 0.1 and 0.2 mg/ kg). Following premedication, anesthesia was induced with 4% isoflurane in oxygen delivered through a mask and connected to a Bain non-rebreathing system. A significantly longer time was taken from the end of general anesthesia to head movement in the high-dose group compared with the saline group (P = 0.002). A significantly longer time was taken from the end of general anesthesia to ambulation in the high-dose group compared with the saline group (P = 0.006). There were no significant differences between groups in the subjective assessment of anesthetic quality or ease of intubation. Premedication with i.m. midazolam at the dosages used did prolong recovery from anesthesia, although to a degree unlikely to be significant clinically. Text Harp Seal Phoca groenlandica BioOne Online Journals Bain ENVELOPE(-65.433,-65.433,-66.550,-66.550) Journal of Zoo and Wildlife Medicine 37 1 27 32 |
institution |
Open Polar |
collection |
BioOne Online Journals |
op_collection_id |
ftbioone |
language |
English |
description |
The purpose of this study was to provide safe anesthesia for bronchoalveolar lavage and assess the utility of premedication with i.m. midazolam for short-duration anesthesia with isoflurane in harp seals (Phoca groenlandica). Fourteen yearling harp seal pups were anesthetized three times each as part of a prospective, cross-over, blinded study. Each animal received i.m. premedication with saline, low-dose, or high-dose midazolam (respectively 0.1 and 0.2 mg/ kg). Following premedication, anesthesia was induced with 4% isoflurane in oxygen delivered through a mask and connected to a Bain non-rebreathing system. A significantly longer time was taken from the end of general anesthesia to head movement in the high-dose group compared with the saline group (P = 0.002). A significantly longer time was taken from the end of general anesthesia to ambulation in the high-dose group compared with the saline group (P = 0.006). There were no significant differences between groups in the subjective assessment of anesthetic quality or ease of intubation. Premedication with i.m. midazolam at the dosages used did prolong recovery from anesthesia, although to a degree unlikely to be significant clinically. |
author2 |
Daniel S. J. Pang Yves Rondenay Lena Measures Stéphane Lair |
format |
Text |
author |
Daniel S. J. Pang Yves Rondenay Lena Measures Stéphane Lair |
spellingShingle |
Daniel S. J. Pang Yves Rondenay Lena Measures Stéphane Lair THE EFFECTS OF TWO DOSAGES OF MIDAZOLAM ON SHORT-DURATION ANESTHESIA IN THE HARP SEAL (PHOCA GROENLANDICA) |
author_facet |
Daniel S. J. Pang Yves Rondenay Lena Measures Stéphane Lair |
author_sort |
Daniel S. J. Pang |
title |
THE EFFECTS OF TWO DOSAGES OF MIDAZOLAM ON SHORT-DURATION ANESTHESIA IN THE HARP SEAL (PHOCA GROENLANDICA) |
title_short |
THE EFFECTS OF TWO DOSAGES OF MIDAZOLAM ON SHORT-DURATION ANESTHESIA IN THE HARP SEAL (PHOCA GROENLANDICA) |
title_full |
THE EFFECTS OF TWO DOSAGES OF MIDAZOLAM ON SHORT-DURATION ANESTHESIA IN THE HARP SEAL (PHOCA GROENLANDICA) |
title_fullStr |
THE EFFECTS OF TWO DOSAGES OF MIDAZOLAM ON SHORT-DURATION ANESTHESIA IN THE HARP SEAL (PHOCA GROENLANDICA) |
title_full_unstemmed |
THE EFFECTS OF TWO DOSAGES OF MIDAZOLAM ON SHORT-DURATION ANESTHESIA IN THE HARP SEAL (PHOCA GROENLANDICA) |
title_sort |
effects of two dosages of midazolam on short-duration anesthesia in the harp seal (phoca groenlandica) |
publisher |
American Association of Zoo Veterinarians |
publishDate |
2006 |
url |
https://doi.org/10.1638/05-052.1 |
op_coverage |
world |
long_lat |
ENVELOPE(-65.433,-65.433,-66.550,-66.550) |
geographic |
Bain |
geographic_facet |
Bain |
genre |
Harp Seal Phoca groenlandica |
genre_facet |
Harp Seal Phoca groenlandica |
op_source |
https://doi.org/10.1638/05-052.1 |
op_relation |
doi:10.1638/05-052.1 |
op_rights |
All rights reserved. |
op_doi |
https://doi.org/10.1638/05-052.1 |
container_title |
Journal of Zoo and Wildlife Medicine |
container_volume |
37 |
container_issue |
1 |
container_start_page |
27 |
op_container_end_page |
32 |
_version_ |
1772815165540007936 |