TP53 EXPRESSING SQUAMOUS CELL CARCINOMA OF THE TONSIL IN A CAPTIVE POLAR WOLF (CANIS LUPUS ARCTOS)

The gross and histopathologic findings for a primary tonsillar squamous cell carcinoma in a captive 11-yr-old male polar wolf (Canis lupus arctos) are described. The carcinoma had metastasized to regional lymph nodes of the pharynx, the precardial mediastinum, and the lungs. Tumor suppressor protein...

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Bibliographic Details
Published in:Journal of Zoo and Wildlife Medicine
Main Authors: Jens P. Teifke, Christiane V. Löhr, Christoph Langner
Format: Text
Language:English
Published: American Association of Zoo Veterinarians 2005
Subjects:
Canis lupus
Online Access:https://doi.org/10.1638/04-019.1
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spelling ftbioone:10.1638/04-019.1 2023-07-30T04:02:48+02:00 TP53 EXPRESSING SQUAMOUS CELL CARCINOMA OF THE TONSIL IN A CAPTIVE POLAR WOLF (CANIS LUPUS ARCTOS) Jens P. Teifke Christiane V. Löhr Christoph Langner Jens P. Teifke Christiane V. Löhr Christoph Langner world 2005-09-01 text/HTML https://doi.org/10.1638/04-019.1 en eng American Association of Zoo Veterinarians doi:10.1638/04-019.1 All rights reserved. https://doi.org/10.1638/04-019.1 Text 2005 ftbioone https://doi.org/10.1638/04-019.1 2023-07-09T10:44:24Z The gross and histopathologic findings for a primary tonsillar squamous cell carcinoma in a captive 11-yr-old male polar wolf (Canis lupus arctos) are described. The carcinoma had metastasized to regional lymph nodes of the pharynx, the precardial mediastinum, and the lungs. Tumor suppressor protein TP53 was detected by immunohistochemistry in the nuclei of poorly differentiated, cytokeratin-positive cells of the primary neoplasm and the metastases. Canine oral papillomavirus DNA was not detectable by polymerase chain reaction (PCR). Text Canis lupus BioOne Online Journals Journal of Zoo and Wildlife Medicine 36 3 538 542
institution Open Polar
collection BioOne Online Journals
op_collection_id ftbioone
language English
description The gross and histopathologic findings for a primary tonsillar squamous cell carcinoma in a captive 11-yr-old male polar wolf (Canis lupus arctos) are described. The carcinoma had metastasized to regional lymph nodes of the pharynx, the precardial mediastinum, and the lungs. Tumor suppressor protein TP53 was detected by immunohistochemistry in the nuclei of poorly differentiated, cytokeratin-positive cells of the primary neoplasm and the metastases. Canine oral papillomavirus DNA was not detectable by polymerase chain reaction (PCR).
author2 Jens P. Teifke
Christiane V. Löhr
Christoph Langner
format Text
author Jens P. Teifke
Christiane V. Löhr
Christoph Langner
spellingShingle Jens P. Teifke
Christiane V. Löhr
Christoph Langner
TP53 EXPRESSING SQUAMOUS CELL CARCINOMA OF THE TONSIL IN A CAPTIVE POLAR WOLF (CANIS LUPUS ARCTOS)
author_facet Jens P. Teifke
Christiane V. Löhr
Christoph Langner
author_sort Jens P. Teifke
title TP53 EXPRESSING SQUAMOUS CELL CARCINOMA OF THE TONSIL IN A CAPTIVE POLAR WOLF (CANIS LUPUS ARCTOS)
title_short TP53 EXPRESSING SQUAMOUS CELL CARCINOMA OF THE TONSIL IN A CAPTIVE POLAR WOLF (CANIS LUPUS ARCTOS)
title_full TP53 EXPRESSING SQUAMOUS CELL CARCINOMA OF THE TONSIL IN A CAPTIVE POLAR WOLF (CANIS LUPUS ARCTOS)
title_fullStr TP53 EXPRESSING SQUAMOUS CELL CARCINOMA OF THE TONSIL IN A CAPTIVE POLAR WOLF (CANIS LUPUS ARCTOS)
title_full_unstemmed TP53 EXPRESSING SQUAMOUS CELL CARCINOMA OF THE TONSIL IN A CAPTIVE POLAR WOLF (CANIS LUPUS ARCTOS)
title_sort tp53 expressing squamous cell carcinoma of the tonsil in a captive polar wolf (canis lupus arctos)
publisher American Association of Zoo Veterinarians
publishDate 2005
url https://doi.org/10.1638/04-019.1
op_coverage world
genre Canis lupus
genre_facet Canis lupus
op_source https://doi.org/10.1638/04-019.1
op_relation doi:10.1638/04-019.1
op_rights All rights reserved.
op_doi https://doi.org/10.1638/04-019.1
container_title Journal of Zoo and Wildlife Medicine
container_volume 36
container_issue 3
container_start_page 538
op_container_end_page 542
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