Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study
Abstract Background The aim of this study was to assess the possible associations between female androgenetic alopecia (AGA), insulin resistance and health-related quality of life (HRQOL)-linked factors in women. We hypothesized that not only the mental aspects but also certain physical aspect of wo...
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ftbiomed:oai:biomedcentral.com:1477-7525-3-49 2023-05-15T17:42:50+02:00 Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study Hirsso, Päivi Rajala, Ulla Laakso, Mauri Hiltunen, Liisa Härkönen, Pirjo Keinänen-Kiukaanniemi, Sirkka 2005-08-24 http://www.hqlo.com/content/3/1/49 en eng BioMed Central Ltd. http://www.hqlo.com/content/3/1/49 Copyright 2005 Hirsso et al; licensee BioMed Central Ltd. androgenic alopecia hair loss insulin resistance health related quality of life Research 2005 ftbiomed 2007-11-11T15:34:27Z Abstract Background The aim of this study was to assess the possible associations between female androgenetic alopecia (AGA), insulin resistance and health-related quality of life (HRQOL)-linked factors in women. We hypothesized that not only the mental aspects but also certain physical aspect of women's health, such as insulin resistance, have an important role in the determination of HRQOL among women with hair loss. Methods A population-based cohort of 330 healthy women aged 63 years, who participated in this study in the City of Oulu in Northern Finland, underwent a medical check-up including assessment of hair status on Ludwig's scale. Background data were collected with a standard questionnaire including a validated RAND 36-Item Health Survey (RAND-36) questionnaire. Results 105 (31%) women with AGA and 225 (69%) controls completed the RAND-36 questionnaire. The women with AGA were more insulin-resistant than the women with normal hair (QUICKI 0.337 vs. 0.346, p = 0.012). Impaired glucose regulation (IGR) was more prevalent among the former than the latter group (39% vs. 25%). The mean RAND-36 scores were significantly lower on the dimensions of physical functioning, role limitation due to physical health and general health, but not on the mental or social dimensions, among the women with AGA compared with the controls. In multivariate logistic regression analyses with the lowest quintiles of the HRQOL dimensions as the dependent variables and AGA, depression, marital status, education and IGR or QUICKI as independent variables, AGA was independently associated with role limitations due to physical health (2.2, 95% CI 1.20–4.05, 2.45 95% CI 1.32–4.55, respectively). Conclusion In women aged 63 years, AGA was associated with role limitations due to physical health. Furthermore, the prevalence rates of IGR and insulin resistance measured by QUICKI were higher among the women with hair loss than those with normal hair. Other/Unknown Material Northern Finland BioMed Central |
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ftbiomed |
language |
English |
topic |
androgenic alopecia hair loss insulin resistance health related quality of life |
spellingShingle |
androgenic alopecia hair loss insulin resistance health related quality of life Hirsso, Päivi Rajala, Ulla Laakso, Mauri Hiltunen, Liisa Härkönen, Pirjo Keinänen-Kiukaanniemi, Sirkka Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study |
topic_facet |
androgenic alopecia hair loss insulin resistance health related quality of life |
description |
Abstract Background The aim of this study was to assess the possible associations between female androgenetic alopecia (AGA), insulin resistance and health-related quality of life (HRQOL)-linked factors in women. We hypothesized that not only the mental aspects but also certain physical aspect of women's health, such as insulin resistance, have an important role in the determination of HRQOL among women with hair loss. Methods A population-based cohort of 330 healthy women aged 63 years, who participated in this study in the City of Oulu in Northern Finland, underwent a medical check-up including assessment of hair status on Ludwig's scale. Background data were collected with a standard questionnaire including a validated RAND 36-Item Health Survey (RAND-36) questionnaire. Results 105 (31%) women with AGA and 225 (69%) controls completed the RAND-36 questionnaire. The women with AGA were more insulin-resistant than the women with normal hair (QUICKI 0.337 vs. 0.346, p = 0.012). Impaired glucose regulation (IGR) was more prevalent among the former than the latter group (39% vs. 25%). The mean RAND-36 scores were significantly lower on the dimensions of physical functioning, role limitation due to physical health and general health, but not on the mental or social dimensions, among the women with AGA compared with the controls. In multivariate logistic regression analyses with the lowest quintiles of the HRQOL dimensions as the dependent variables and AGA, depression, marital status, education and IGR or QUICKI as independent variables, AGA was independently associated with role limitations due to physical health (2.2, 95% CI 1.20–4.05, 2.45 95% CI 1.32–4.55, respectively). Conclusion In women aged 63 years, AGA was associated with role limitations due to physical health. Furthermore, the prevalence rates of IGR and insulin resistance measured by QUICKI were higher among the women with hair loss than those with normal hair. |
format |
Other/Unknown Material |
author |
Hirsso, Päivi Rajala, Ulla Laakso, Mauri Hiltunen, Liisa Härkönen, Pirjo Keinänen-Kiukaanniemi, Sirkka |
author_facet |
Hirsso, Päivi Rajala, Ulla Laakso, Mauri Hiltunen, Liisa Härkönen, Pirjo Keinänen-Kiukaanniemi, Sirkka |
author_sort |
Hirsso, Päivi |
title |
Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study |
title_short |
Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study |
title_full |
Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study |
title_fullStr |
Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study |
title_full_unstemmed |
Health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a Finnish population-based study |
title_sort |
health-related quality of life and physical well-being among a 63-year-old cohort of women with androgenetic alopecia; a finnish population-based study |
publisher |
BioMed Central Ltd. |
publishDate |
2005 |
url |
http://www.hqlo.com/content/3/1/49 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_relation |
http://www.hqlo.com/content/3/1/49 |
op_rights |
Copyright 2005 Hirsso et al; licensee BioMed Central Ltd. |
_version_ |
1766144748078235648 |