Modelling substrate specificity and enantioselectivity for lipases and esterases by substrate-imprinted docking
Abstract Background Previously, ways to adapt docking programs that were developed for modelling inhibitor-receptor interaction have been explored. Two main issues were discussed. First, when trying to model catalysis a reaction intermediate of the substrate is expected to provide more valid informa...
| Main Authors: | , , , |
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| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
BioMed Central Ltd.
2009
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| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1472-6807/9/39 |