Diabetes in pregnancy among First Nations women in Alberta, Canada: a retrospective analysis
Abstract Background In addition to increasing the risk of adverse birth outcomes, diabetes in pregnancy is thought to be an important driver of the epidemic of type 2 diabetes affecting Canada’s First Nations population. The relative contributions of gestational diabetes mellitus (GDM) and pre-exist...
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ftbiomed:oai:biomedcentral.com:1471-2393-14-136 2023-05-15T16:13:53+02:00 Diabetes in pregnancy among First Nations women in Alberta, Canada: a retrospective analysis Oster, Richard T King, Malcolm Morrish, Donald W Mayan, Maria J Toth, Ellen L 2014-04-10 http://www.biomedcentral.com/1471-2393/14/136 en eng BioMed Central Ltd. http://www.biomedcentral.com/1471-2393/14/136 Copyright 2014 Oster et al.; licensee BioMed Central Ltd. Indigenous population Gestational diabetes Pregnancy in diabetes Epidemiology Retrospective study Research article 2014 ftbiomed 2014-04-20T00:27:57Z Abstract Background In addition to increasing the risk of adverse birth outcomes, diabetes in pregnancy is thought to be an important driver of the epidemic of type 2 diabetes affecting Canada’s First Nations population. The relative contributions of gestational diabetes mellitus (GDM) and pre-existing diabetes are not well understood. We generated a comprehensive epidemiological profile of diabetes in pregnancy over a 10-year period among the First Nations population of Alberta, Canada. Methods De-identified administrative data for 427,058 delivery records were obtained for the years 2000–2009. Pregnancy risk factors and delivery outcomes were described and compared by ethnicity (First Nations vs. non-First Nations) and diabetes status. Age-adjusted prevalence values for GDM and pre-existing diabetes were calculated and were compared by ethnicity. Longitudinal changes over time were also examined. Predictors were explored using logistic regression analysis. Results First Nations women had more antenatal risk factors and adverse infant outcomes that were compounded by diabetes. First Nations descent was an independent predictor of diabetes in pregnancy (p < 0.001). GDM prevalence was significantly higher among First Nations (6.1%) compared to non-First Nations women (3.8%; p < 0.001), but prevalence values increased significantly over time only in non-First Nations women (4.5 average annual percent change; p < 0.05). The prevalence of pre-existing diabetes was stable over time in both groups, but First Nations women experienced a 2.5-fold higher overall prevalence compared with non-First Nations women (1.5% vs. 0.6%, respectively; p < 0.001). Conclusions Although First Nations women experience a higher overall prevalence of diabetes in pregnancy, the lack of increase in the prevalence over time is encouraging. However, because high-risk pregnancies and poor outcomes are more common among First Nations women, particularly those with diabetes, strategies to improve perinatal care must be implemented. Article in Journal/Newspaper First Nations BioMed Central Canada |
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Indigenous population Gestational diabetes Pregnancy in diabetes Epidemiology Retrospective study |
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Indigenous population Gestational diabetes Pregnancy in diabetes Epidemiology Retrospective study Oster, Richard T King, Malcolm Morrish, Donald W Mayan, Maria J Toth, Ellen L Diabetes in pregnancy among First Nations women in Alberta, Canada: a retrospective analysis |
topic_facet |
Indigenous population Gestational diabetes Pregnancy in diabetes Epidemiology Retrospective study |
description |
Abstract Background In addition to increasing the risk of adverse birth outcomes, diabetes in pregnancy is thought to be an important driver of the epidemic of type 2 diabetes affecting Canada’s First Nations population. The relative contributions of gestational diabetes mellitus (GDM) and pre-existing diabetes are not well understood. We generated a comprehensive epidemiological profile of diabetes in pregnancy over a 10-year period among the First Nations population of Alberta, Canada. Methods De-identified administrative data for 427,058 delivery records were obtained for the years 2000–2009. Pregnancy risk factors and delivery outcomes were described and compared by ethnicity (First Nations vs. non-First Nations) and diabetes status. Age-adjusted prevalence values for GDM and pre-existing diabetes were calculated and were compared by ethnicity. Longitudinal changes over time were also examined. Predictors were explored using logistic regression analysis. Results First Nations women had more antenatal risk factors and adverse infant outcomes that were compounded by diabetes. First Nations descent was an independent predictor of diabetes in pregnancy (p < 0.001). GDM prevalence was significantly higher among First Nations (6.1%) compared to non-First Nations women (3.8%; p < 0.001), but prevalence values increased significantly over time only in non-First Nations women (4.5 average annual percent change; p < 0.05). The prevalence of pre-existing diabetes was stable over time in both groups, but First Nations women experienced a 2.5-fold higher overall prevalence compared with non-First Nations women (1.5% vs. 0.6%, respectively; p < 0.001). Conclusions Although First Nations women experience a higher overall prevalence of diabetes in pregnancy, the lack of increase in the prevalence over time is encouraging. However, because high-risk pregnancies and poor outcomes are more common among First Nations women, particularly those with diabetes, strategies to improve perinatal care must be implemented. |
format |
Article in Journal/Newspaper |
author |
Oster, Richard T King, Malcolm Morrish, Donald W Mayan, Maria J Toth, Ellen L |
author_facet |
Oster, Richard T King, Malcolm Morrish, Donald W Mayan, Maria J Toth, Ellen L |
author_sort |
Oster, Richard T |
title |
Diabetes in pregnancy among First Nations women in Alberta, Canada: a retrospective analysis |
title_short |
Diabetes in pregnancy among First Nations women in Alberta, Canada: a retrospective analysis |
title_full |
Diabetes in pregnancy among First Nations women in Alberta, Canada: a retrospective analysis |
title_fullStr |
Diabetes in pregnancy among First Nations women in Alberta, Canada: a retrospective analysis |
title_full_unstemmed |
Diabetes in pregnancy among First Nations women in Alberta, Canada: a retrospective analysis |
title_sort |
diabetes in pregnancy among first nations women in alberta, canada: a retrospective analysis |
publisher |
BioMed Central Ltd. |
publishDate |
2014 |
url |
http://www.biomedcentral.com/1471-2393/14/136 |
geographic |
Canada |
geographic_facet |
Canada |
genre |
First Nations |
genre_facet |
First Nations |
op_relation |
http://www.biomedcentral.com/1471-2393/14/136 |
op_rights |
Copyright 2014 Oster et al.; licensee BioMed Central Ltd. |
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1765999744666042368 |