Residential crowding and severe respiratory syncytial virus disease among infants and young children: A systematic literature review
Abstract Background The objective of this literature review was to determine whether crowding in the home is associated with an increased risk of severe respiratory syncytial virus (RSV) disease in children younger than 5 years. Methods A computerized literature search of PubMed and EMBASE was condu...
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ftbiomed:oai:biomedcentral.com:1471-2334-12-95 2023-05-15T16:55:19+02:00 Residential crowding and severe respiratory syncytial virus disease among infants and young children: A systematic literature review Colosia, Ann D Masaquel, Anthony Hall, Caroline Barrett, Amy M Mahadevia, Parthiv J Yogev, Ram 2012-04-20 http://www.biomedcentral.com/1471-2334/12/95 en eng BioMed Central Ltd. http://www.biomedcentral.com/1471-2334/12/95 Copyright 2012 Colosia et al.; licensee BioMed Central Ltd. Respiratory syncytial virus Respiratory infection Crowding Children Research article 2012 ftbiomed 2012-07-28T23:52:48Z Abstract Background The objective of this literature review was to determine whether crowding in the home is associated with an increased risk of severe respiratory syncytial virus (RSV) disease in children younger than 5 years. Methods A computerized literature search of PubMed and EMBASE was conducted on residential crowding as a risk factor for laboratory-confirmed RSV illness in children younger than 5 years. Study populations were stratified by high-risk populations, defined by prematurity, chronic lung disease of prematurity, hemodynamically significant congenital heart disease, or specific at-risk ethnicity (i.e. Alaska Native, Inuit), and mixed-risk populations, including general populations of mostly healthy children. The search was conducted for articles published from January 1, 1985, to October 8, 2009, and was limited to studies reported in English. To avoid indexing bias in the computerized databases, the search included terms for multivariate analysis and risk factors to identify studies in which residential crowding was evaluated but was not significant. Methodological quality of included studies was assessed using a Cochrane risk of bias tool. Results The search identified 20 relevant studies that were conducted in geographically diverse locations. Among studies of patients in high-risk populations, 7 of 9 found a statistically significant association with a crowding variable; in studies in mixed-risk populations, 9 of 11 found a significant association with a crowding variable. In studies of high-risk children, residential crowding significantly increased the odds of laboratory-confirmed RSV hospitalization (i.e. odds ratio ranged from 1.45 to 2.85). In studies of mixed-risk populations, the adjusted odds ratios ranged from 1.23 to 9.1. The findings on the effect of residential crowding on outpatient RSV lower respiratory tract infection were inconsistent. Conclusions Residential crowding was associated with an increased risk of laboratory-confirmed RSV hospitalization among high-risk infants and young children. This association was consistent despite differences in definitions of residential crowding, populations, or geographic locations. Article in Journal/Newspaper inuit Alaska BioMed Central |
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Respiratory syncytial virus Respiratory infection Crowding Children |
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Respiratory syncytial virus Respiratory infection Crowding Children Colosia, Ann D Masaquel, Anthony Hall, Caroline Barrett, Amy M Mahadevia, Parthiv J Yogev, Ram Residential crowding and severe respiratory syncytial virus disease among infants and young children: A systematic literature review |
topic_facet |
Respiratory syncytial virus Respiratory infection Crowding Children |
description |
Abstract Background The objective of this literature review was to determine whether crowding in the home is associated with an increased risk of severe respiratory syncytial virus (RSV) disease in children younger than 5 years. Methods A computerized literature search of PubMed and EMBASE was conducted on residential crowding as a risk factor for laboratory-confirmed RSV illness in children younger than 5 years. Study populations were stratified by high-risk populations, defined by prematurity, chronic lung disease of prematurity, hemodynamically significant congenital heart disease, or specific at-risk ethnicity (i.e. Alaska Native, Inuit), and mixed-risk populations, including general populations of mostly healthy children. The search was conducted for articles published from January 1, 1985, to October 8, 2009, and was limited to studies reported in English. To avoid indexing bias in the computerized databases, the search included terms for multivariate analysis and risk factors to identify studies in which residential crowding was evaluated but was not significant. Methodological quality of included studies was assessed using a Cochrane risk of bias tool. Results The search identified 20 relevant studies that were conducted in geographically diverse locations. Among studies of patients in high-risk populations, 7 of 9 found a statistically significant association with a crowding variable; in studies in mixed-risk populations, 9 of 11 found a significant association with a crowding variable. In studies of high-risk children, residential crowding significantly increased the odds of laboratory-confirmed RSV hospitalization (i.e. odds ratio ranged from 1.45 to 2.85). In studies of mixed-risk populations, the adjusted odds ratios ranged from 1.23 to 9.1. The findings on the effect of residential crowding on outpatient RSV lower respiratory tract infection were inconsistent. Conclusions Residential crowding was associated with an increased risk of laboratory-confirmed RSV hospitalization among high-risk infants and young children. This association was consistent despite differences in definitions of residential crowding, populations, or geographic locations. |
format |
Article in Journal/Newspaper |
author |
Colosia, Ann D Masaquel, Anthony Hall, Caroline Barrett, Amy M Mahadevia, Parthiv J Yogev, Ram |
author_facet |
Colosia, Ann D Masaquel, Anthony Hall, Caroline Barrett, Amy M Mahadevia, Parthiv J Yogev, Ram |
author_sort |
Colosia, Ann D |
title |
Residential crowding and severe respiratory syncytial virus disease among infants and young children: A systematic literature review |
title_short |
Residential crowding and severe respiratory syncytial virus disease among infants and young children: A systematic literature review |
title_full |
Residential crowding and severe respiratory syncytial virus disease among infants and young children: A systematic literature review |
title_fullStr |
Residential crowding and severe respiratory syncytial virus disease among infants and young children: A systematic literature review |
title_full_unstemmed |
Residential crowding and severe respiratory syncytial virus disease among infants and young children: A systematic literature review |
title_sort |
residential crowding and severe respiratory syncytial virus disease among infants and young children: a systematic literature review |
publisher |
BioMed Central Ltd. |
publishDate |
2012 |
url |
http://www.biomedcentral.com/1471-2334/12/95 |
genre |
inuit Alaska |
genre_facet |
inuit Alaska |
op_relation |
http://www.biomedcentral.com/1471-2334/12/95 |
op_rights |
Copyright 2012 Colosia et al.; licensee BioMed Central Ltd. |
_version_ |
1766046298945880064 |