Cross-sectional associations between prevalent vertebral fracture and pulmonary function in the sixth Tromsø study
Abstract Background Persons with vertebral fracture may have reduced pulmonary function, but this association has not been much studied. The aim of this cross-sectional study was therefore to examine the relationship between vertebral fracture and pulmonary function in a general, elderly population....
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ftbiomed:oai:biomedcentral.com:1471-2318-13-116 2023-05-15T18:34:26+02:00 Cross-sectional associations between prevalent vertebral fracture and pulmonary function in the sixth Tromsø study Morseth, Bente Melbye, Hasse Waterloo, Svanhild Thomassen, Marte R Risberg, Marijke J Emaus, Nina 2013-10-29 http://www.biomedcentral.com/1471-2318/13/116 en eng BioMed Central Ltd. http://www.biomedcentral.com/1471-2318/13/116 Copyright 2013 Morseth et al.; licensee BioMed Central Ltd. Vertebral fractures Pulmonary function Lung function Population study Epidemiology Elderly Research article 2013 ftbiomed 2013-11-10T01:21:57Z Abstract Background Persons with vertebral fracture may have reduced pulmonary function, but this association has not been much studied. The aim of this cross-sectional study was therefore to examine the relationship between vertebral fracture and pulmonary function in a general, elderly population. Methods Vertebral morphometry was used for vertebral fracture assessment in 2132 elderly men (n = 892) and women (n = 1240) aged 55 to 87 years in the population-based Tromsø Study 2007–08. Pulmonary function was examined by spirometry. Pulmonary function was expressed as FVC% predicted, FEV 1 % predicted, and FEV 1 /FVC% predicted values, adjusted FVC, FEV 1 , and FEV 1 /FVC, and obstructive and restrictive ventilatory impairment. Vertebral fracture was classified according to appearance, number, severity, and location of fractures. Associations were analyzed using general linear and logistic models. Results FVC% predicted and FEV 1 % predicted values were not associated with vertebral fracture (P > 0.05), whereas FEV 1 /FVC% predicted ratio was associated with both prevalent fracture, number of fractures, severity of fractures, and fracture site in men (P < 0.05), but not in women. When FVC, FEV 1 , and FEV 1 /FVC values were adjusted for multiple covariates, we found no significant association with vertebral fracture. Obstructive and restrictive ventilatory impairment was not associated with prevalent vertebral fracture. Conclusions In conclusion, this study did not confirm any clinically relevant associations between prevalent vertebral fracture and ventilatory impairment in elderly individuals. Article in Journal/Newspaper Tromsø BioMed Central Tromsø |
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English |
topic |
Vertebral fractures Pulmonary function Lung function Population study Epidemiology Elderly |
spellingShingle |
Vertebral fractures Pulmonary function Lung function Population study Epidemiology Elderly Morseth, Bente Melbye, Hasse Waterloo, Svanhild Thomassen, Marte R Risberg, Marijke J Emaus, Nina Cross-sectional associations between prevalent vertebral fracture and pulmonary function in the sixth Tromsø study |
topic_facet |
Vertebral fractures Pulmonary function Lung function Population study Epidemiology Elderly |
description |
Abstract Background Persons with vertebral fracture may have reduced pulmonary function, but this association has not been much studied. The aim of this cross-sectional study was therefore to examine the relationship between vertebral fracture and pulmonary function in a general, elderly population. Methods Vertebral morphometry was used for vertebral fracture assessment in 2132 elderly men (n = 892) and women (n = 1240) aged 55 to 87 years in the population-based Tromsø Study 2007–08. Pulmonary function was examined by spirometry. Pulmonary function was expressed as FVC% predicted, FEV 1 % predicted, and FEV 1 /FVC% predicted values, adjusted FVC, FEV 1 , and FEV 1 /FVC, and obstructive and restrictive ventilatory impairment. Vertebral fracture was classified according to appearance, number, severity, and location of fractures. Associations were analyzed using general linear and logistic models. Results FVC% predicted and FEV 1 % predicted values were not associated with vertebral fracture (P > 0.05), whereas FEV 1 /FVC% predicted ratio was associated with both prevalent fracture, number of fractures, severity of fractures, and fracture site in men (P < 0.05), but not in women. When FVC, FEV 1 , and FEV 1 /FVC values were adjusted for multiple covariates, we found no significant association with vertebral fracture. Obstructive and restrictive ventilatory impairment was not associated with prevalent vertebral fracture. Conclusions In conclusion, this study did not confirm any clinically relevant associations between prevalent vertebral fracture and ventilatory impairment in elderly individuals. |
format |
Article in Journal/Newspaper |
author |
Morseth, Bente Melbye, Hasse Waterloo, Svanhild Thomassen, Marte R Risberg, Marijke J Emaus, Nina |
author_facet |
Morseth, Bente Melbye, Hasse Waterloo, Svanhild Thomassen, Marte R Risberg, Marijke J Emaus, Nina |
author_sort |
Morseth, Bente |
title |
Cross-sectional associations between prevalent vertebral fracture and pulmonary function in the sixth Tromsø study |
title_short |
Cross-sectional associations between prevalent vertebral fracture and pulmonary function in the sixth Tromsø study |
title_full |
Cross-sectional associations between prevalent vertebral fracture and pulmonary function in the sixth Tromsø study |
title_fullStr |
Cross-sectional associations between prevalent vertebral fracture and pulmonary function in the sixth Tromsø study |
title_full_unstemmed |
Cross-sectional associations between prevalent vertebral fracture and pulmonary function in the sixth Tromsø study |
title_sort |
cross-sectional associations between prevalent vertebral fracture and pulmonary function in the sixth tromsø study |
publisher |
BioMed Central Ltd. |
publishDate |
2013 |
url |
http://www.biomedcentral.com/1471-2318/13/116 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
http://www.biomedcentral.com/1471-2318/13/116 |
op_rights |
Copyright 2013 Morseth et al.; licensee BioMed Central Ltd. |
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