Vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007–08
Abstract Background Health-related quality of life (HRQL) may be associated with increased mortality in the elderly. The effect of prevalent vertebral fractures on HRQL in elderly women and men is not well described. The purpose of this study was to examine the association between prevalent vertebra...
Main Authors: | , , , , , |
---|---|
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BioMed Central Ltd.
2013
|
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2318/13/102 |
id |
ftbiomed:oai:biomedcentral.com:1471-2318-13-102 |
---|---|
record_format |
openpolar |
spelling |
ftbiomed:oai:biomedcentral.com:1471-2318-13-102 2023-05-15T18:34:34+02:00 Vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007–08 Waterloo, Svanhild Søgaard, Anne J Ahmed, Luai A Damsgård, Elin Morseth, Bente Emaus, Nina 2013-09-30 http://www.biomedcentral.com/1471-2318/13/102 en eng BioMed Central Ltd. http://www.biomedcentral.com/1471-2318/13/102 Copyright 2013 Waterloo et al.; licensee BioMed Central Ltd. Vertebral fractures Health-related quality of life (HRQL) Self-perceived health Pain Population-based study Research article 2013 ftbiomed 2013-11-03T01:21:53Z Abstract Background Health-related quality of life (HRQL) may be associated with increased mortality in the elderly. The effect of prevalent vertebral fractures on HRQL in elderly women and men is not well described. The purpose of this study was to examine the association between prevalent vertebral fractures and back pain, neck pain, and HRQL in elderly women and men, and to study possible gender differences in the reported pain and HRQL. Methods Information on prevalent vertebral fractures was ascertained by a vertebral fracture assessment (VFA) method (dual-energy X-ray absorptiometry (DXA), GE Lunar Prodigy) in 2887 women and men, mean age 65.4 (SD 9.4) who participated in the population-based Tromsø Study which was conducted in 2007–08. Bone mineral density (BMD; g/cm 2 ) was measured by DXA at the femoral sites. Self-reported HRQL was assessed using the standardized measures EQ-5D-3 L and EQ VAS from the EuroQol Group. Lifestyle information was collected by questionnaires. The association between vertebral fractures and pain was analyzed using logistic regression, between vertebral fractures and EQ-5D-3 L and EQ VAS scores by multiple regression analyses. Results In women, presence of vertebral fractures was associated with an increased risk of back pain with an OR of 1.76 (95% CI: 1.24 – 2.50) after adjustments for age, height, weight, and BMD. Women with vertebral fractures had lower EQ-5D-3 L scores (p < 0.001) than women without vertebral fractures, also after adjustments. These associations were not present in men. Type of fracture was not associated with EQ-5D-3 L scores, but increasing numbers (p < 0.001) and severity of fractures (p < 0.002) were associated with decreasing EQ-5D-3 L score in women. Conclusion Prevalent vertebral fractures are associated with increased risk of back pain and reduced HRQL in postmenopausal women, but not in men. Article in Journal/Newspaper Tromsø BioMed Central Tromsø |
institution |
Open Polar |
collection |
BioMed Central |
op_collection_id |
ftbiomed |
language |
English |
topic |
Vertebral fractures Health-related quality of life (HRQL) Self-perceived health Pain Population-based study |
spellingShingle |
Vertebral fractures Health-related quality of life (HRQL) Self-perceived health Pain Population-based study Waterloo, Svanhild Søgaard, Anne J Ahmed, Luai A Damsgård, Elin Morseth, Bente Emaus, Nina Vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007–08 |
topic_facet |
Vertebral fractures Health-related quality of life (HRQL) Self-perceived health Pain Population-based study |
description |
Abstract Background Health-related quality of life (HRQL) may be associated with increased mortality in the elderly. The effect of prevalent vertebral fractures on HRQL in elderly women and men is not well described. The purpose of this study was to examine the association between prevalent vertebral fractures and back pain, neck pain, and HRQL in elderly women and men, and to study possible gender differences in the reported pain and HRQL. Methods Information on prevalent vertebral fractures was ascertained by a vertebral fracture assessment (VFA) method (dual-energy X-ray absorptiometry (DXA), GE Lunar Prodigy) in 2887 women and men, mean age 65.4 (SD 9.4) who participated in the population-based Tromsø Study which was conducted in 2007–08. Bone mineral density (BMD; g/cm 2 ) was measured by DXA at the femoral sites. Self-reported HRQL was assessed using the standardized measures EQ-5D-3 L and EQ VAS from the EuroQol Group. Lifestyle information was collected by questionnaires. The association between vertebral fractures and pain was analyzed using logistic regression, between vertebral fractures and EQ-5D-3 L and EQ VAS scores by multiple regression analyses. Results In women, presence of vertebral fractures was associated with an increased risk of back pain with an OR of 1.76 (95% CI: 1.24 – 2.50) after adjustments for age, height, weight, and BMD. Women with vertebral fractures had lower EQ-5D-3 L scores (p < 0.001) than women without vertebral fractures, also after adjustments. These associations were not present in men. Type of fracture was not associated with EQ-5D-3 L scores, but increasing numbers (p < 0.001) and severity of fractures (p < 0.002) were associated with decreasing EQ-5D-3 L score in women. Conclusion Prevalent vertebral fractures are associated with increased risk of back pain and reduced HRQL in postmenopausal women, but not in men. |
format |
Article in Journal/Newspaper |
author |
Waterloo, Svanhild Søgaard, Anne J Ahmed, Luai A Damsgård, Elin Morseth, Bente Emaus, Nina |
author_facet |
Waterloo, Svanhild Søgaard, Anne J Ahmed, Luai A Damsgård, Elin Morseth, Bente Emaus, Nina |
author_sort |
Waterloo, Svanhild |
title |
Vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007–08 |
title_short |
Vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007–08 |
title_full |
Vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007–08 |
title_fullStr |
Vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007–08 |
title_full_unstemmed |
Vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007–08 |
title_sort |
vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the tromsø study 2007–08 |
publisher |
BioMed Central Ltd. |
publishDate |
2013 |
url |
http://www.biomedcentral.com/1471-2318/13/102 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
http://www.biomedcentral.com/1471-2318/13/102 |
op_rights |
Copyright 2013 Waterloo et al.; licensee BioMed Central Ltd. |
_version_ |
1766219378757468160 |