Land ahead: using genome scans to identify molecular markers of adaptive relevance
Adaptation is back on the research schedules of evolutionists and ecologists. This renewed interest is driven by globalchange, to which species, in particular arctic and alpine ones, either react by migration or adaptation. In this overview, wegive a brief introduction to the use of genome scans alo...
Published in: | Plant Ecology & Diversity |
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2008
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Online Access: | https://arbor.bfh.ch/15236/1/Holderegger_PlantEcologyandevolution_2008.pdf https://arbor.bfh.ch/15236/ https://www.tandfonline.com/doi/full/10.1080/17550870802338420 |
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ftbernerfhs:oai:arbor.bfh.ch:15236 2023-05-15T15:12:22+02:00 Land ahead: using genome scans to identify molecular markers of adaptive relevance Herrmann, Doris Poncet, Bénédicte Gugerli, Felix Thuiller, Wilfried Taberlet, Pierre Gielly, Ludovic Rioux, Delphine Brodbeck, Sabine Aubert, Serge Manel, Stéphanie Holderegger, Rolf 2008 application/pdf https://arbor.bfh.ch/15236/1/Holderegger_PlantEcologyandevolution_2008.pdf https://arbor.bfh.ch/15236/ https://www.tandfonline.com/doi/full/10.1080/17550870802338420 eng eng Taylor & Francis https://arbor.bfh.ch/15236/ Holderegger, Rolf; Herrmann, Doris; Poncet, Bénédicte; Gugerli, Felix; Thuiller, Wilfried; Taberlet, Pierre; Gielly, Ludovic; Rioux, Delphine; Brodbeck, Sabine; Aubert, Serge; Manel, Stéphanie (2008). Land ahead: using genome scans to identify molecular markers of adaptive relevance Plant Ecology & Diversity, 1(2), pp. 273-283. Taylor & Francis 10.1080/17550870802338420 <http://dx.doi.org/10.1080/17550870802338420> info:eu-repo/semantics/restrictedAccess Holderegger, Rolf; Herrmann, Doris; Poncet, Bénédicte; Gugerli, Felix; Thuiller, Wilfried; Taberlet, Pierre; Gielly, Ludovic; Rioux, Delphine; Brodbeck, Sabine; Aubert, Serge; Manel, Stéphanie (2008). Land ahead: using genome scans to identify molecular markers of adaptive relevance Plant Ecology & Diversity, 1(2), pp. 273-283. Taylor & Francis 10.1080/17550870802338420 <http://dx.doi.org/10.1080/17550870802338420> QK Botany info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed 2008 ftbernerfhs https://doi.org/10.1080/17550870802338420 2022-03-10T11:16:55Z Adaptation is back on the research schedules of evolutionists and ecologists. This renewed interest is driven by globalchange, to which species, in particular arctic and alpine ones, either react by migration or adaptation. In this overview, wegive a brief introduction to the use of genome scans along with environmental data to identify molecular markers of adap-tive relevance. This approach encompasses the sampling of many populations along ecological gradients or from differenthabitat types combined with genome scans using presumably neutral markers such as amplified fragment length polymor-phisms or microsatellites. To identify markers linked to genes under selection, two different methods (besides others) areparticularly relevant. (1) One searches for markers exhibiting higher genetic differentiation among populations thanexpected under neutrality. The frequencies of alleles at such outlier loci can then be related to ecological factors. (2) Theother method uses logistic regression between allele presence/absence and ecological factors (i.e. an allele distributionmodel). It thus directly links marker occurrence with environmental data. We illustrate these two methods with examplesfrom the literature. The strength of genome scans used in parallel with environmental data is that they provide distinct cluesfor selective forces acting on molecular markers of adaptive relevance in real landscapes. We further discuss limitations ofgenome scans (e.g. sensitivity to phylogeographic structure and bottlenecks) and of other genomic approaches to detectadaptive molecular markers such as candidate genes, quantitative trait loci or transcription profiling. We stress that theselective advantage of particular alleles has to be proven in selection experiments. We conclude that combining studies onadaptive and neutral molecular markers will largely contribute to our understanding of how species react to global changeand will allow us to investigate the ‘migration of adaptation’. Article in Journal/Newspaper Arctic Bern University of Applied Sciences: ARBOR Arctic Tive ENVELOPE(12.480,12.480,65.107,65.107) Plant Ecology & Diversity 1 2 273 283 |
institution |
Open Polar |
collection |
Bern University of Applied Sciences: ARBOR |
op_collection_id |
ftbernerfhs |
language |
English |
topic |
QK Botany |
spellingShingle |
QK Botany Herrmann, Doris Poncet, Bénédicte Gugerli, Felix Thuiller, Wilfried Taberlet, Pierre Gielly, Ludovic Rioux, Delphine Brodbeck, Sabine Aubert, Serge Manel, Stéphanie Land ahead: using genome scans to identify molecular markers of adaptive relevance |
topic_facet |
QK Botany |
description |
Adaptation is back on the research schedules of evolutionists and ecologists. This renewed interest is driven by globalchange, to which species, in particular arctic and alpine ones, either react by migration or adaptation. In this overview, wegive a brief introduction to the use of genome scans along with environmental data to identify molecular markers of adap-tive relevance. This approach encompasses the sampling of many populations along ecological gradients or from differenthabitat types combined with genome scans using presumably neutral markers such as amplified fragment length polymor-phisms or microsatellites. To identify markers linked to genes under selection, two different methods (besides others) areparticularly relevant. (1) One searches for markers exhibiting higher genetic differentiation among populations thanexpected under neutrality. The frequencies of alleles at such outlier loci can then be related to ecological factors. (2) Theother method uses logistic regression between allele presence/absence and ecological factors (i.e. an allele distributionmodel). It thus directly links marker occurrence with environmental data. We illustrate these two methods with examplesfrom the literature. The strength of genome scans used in parallel with environmental data is that they provide distinct cluesfor selective forces acting on molecular markers of adaptive relevance in real landscapes. We further discuss limitations ofgenome scans (e.g. sensitivity to phylogeographic structure and bottlenecks) and of other genomic approaches to detectadaptive molecular markers such as candidate genes, quantitative trait loci or transcription profiling. We stress that theselective advantage of particular alleles has to be proven in selection experiments. We conclude that combining studies onadaptive and neutral molecular markers will largely contribute to our understanding of how species react to global changeand will allow us to investigate the ‘migration of adaptation’. |
author2 |
Holderegger, Rolf |
format |
Article in Journal/Newspaper |
author |
Herrmann, Doris Poncet, Bénédicte Gugerli, Felix Thuiller, Wilfried Taberlet, Pierre Gielly, Ludovic Rioux, Delphine Brodbeck, Sabine Aubert, Serge Manel, Stéphanie |
author_facet |
Herrmann, Doris Poncet, Bénédicte Gugerli, Felix Thuiller, Wilfried Taberlet, Pierre Gielly, Ludovic Rioux, Delphine Brodbeck, Sabine Aubert, Serge Manel, Stéphanie |
author_sort |
Herrmann, Doris |
title |
Land ahead: using genome scans to identify molecular markers of adaptive relevance |
title_short |
Land ahead: using genome scans to identify molecular markers of adaptive relevance |
title_full |
Land ahead: using genome scans to identify molecular markers of adaptive relevance |
title_fullStr |
Land ahead: using genome scans to identify molecular markers of adaptive relevance |
title_full_unstemmed |
Land ahead: using genome scans to identify molecular markers of adaptive relevance |
title_sort |
land ahead: using genome scans to identify molecular markers of adaptive relevance |
publisher |
Taylor & Francis |
publishDate |
2008 |
url |
https://arbor.bfh.ch/15236/1/Holderegger_PlantEcologyandevolution_2008.pdf https://arbor.bfh.ch/15236/ https://www.tandfonline.com/doi/full/10.1080/17550870802338420 |
long_lat |
ENVELOPE(12.480,12.480,65.107,65.107) |
geographic |
Arctic Tive |
geographic_facet |
Arctic Tive |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Holderegger, Rolf; Herrmann, Doris; Poncet, Bénédicte; Gugerli, Felix; Thuiller, Wilfried; Taberlet, Pierre; Gielly, Ludovic; Rioux, Delphine; Brodbeck, Sabine; Aubert, Serge; Manel, Stéphanie (2008). Land ahead: using genome scans to identify molecular markers of adaptive relevance Plant Ecology & Diversity, 1(2), pp. 273-283. Taylor & Francis 10.1080/17550870802338420 <http://dx.doi.org/10.1080/17550870802338420> |
op_relation |
https://arbor.bfh.ch/15236/ Holderegger, Rolf; Herrmann, Doris; Poncet, Bénédicte; Gugerli, Felix; Thuiller, Wilfried; Taberlet, Pierre; Gielly, Ludovic; Rioux, Delphine; Brodbeck, Sabine; Aubert, Serge; Manel, Stéphanie (2008). Land ahead: using genome scans to identify molecular markers of adaptive relevance Plant Ecology & Diversity, 1(2), pp. 273-283. Taylor & Francis 10.1080/17550870802338420 <http://dx.doi.org/10.1080/17550870802338420> |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1080/17550870802338420 |
container_title |
Plant Ecology & Diversity |
container_volume |
1 |
container_issue |
2 |
container_start_page |
273 |
op_container_end_page |
283 |
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1766343057900306432 |