Coverage with timely administered vaccination against hepatitis b virus and its influence on the prevalence of HBV infection in the regions of different endemicity

• Published in: Vaccines
• Main Authors: Kyuregyan, K. K., Kichatova, V. S., Isaeva, O. V., Potemkin, I. A., Oglezneva, E. E.
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2021
• Subjects: medicine; medical virology; hepatitis B vaccine; birth dose coverage; HBV prevalence; hepatitis B epidemiology; public health; Yakutia
• Online Access: http://dspace.bsu.edu.ru/handle/123456789/41258

The principal reason for the absence of HepB-BD was parent refusal, which accounted for 63.5% of cases of non-vaccination (83/123). While timely HepB-2nd coverage was only 55.4%-64.7%: HepB3 coverage by the age of one year exceeded 90% in both study regions. HBV surface antigen (HBsAg) prevalence in the 1998-2019 birth cohort was 0.2% (95% CI: 0.01-1.3%) in Belgorod Oblast and 3.2% (95% CI: 1.9-5.2%) in Yakutia. The proportion of persons testing negative for both antibodies to HBsAg (anti-HBs) and antibodies to HBV core antigen (anti-HBc) in the 1998-2019 birth cohort was 26.2% (125/481) in Belgorod Oblast and 32.3% (162/501) in Yakutia