Development and validation of methods of quantitative determination of the new antidiabetic drug in the blood plasma of rats by high performance liquid chromatography with mass spectrometric detection

• Published in: RESEARCH RESULT Pharmacology and Clinical Pharmacology
• Main Authors: Buzov, A. A., Kulikov, A. L., Avtina, T. V., Pokrovskii, M. V., Osipova, O. A.
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2016
• Subjects: medicine; pharmacology; antidiabetic agent; the blood plasma of rats; high-performance liquid chromatography; mass spectrometric detection; validation; Carbonic acid
• Online Access: http://dspace.bsu.edu.ru/handle/123456789/29281

We developed a method of quantification of the new antidiabetic drug 3-(1h-benzimidazole-2-yl)-1,2,2-trimethyl-cyclopentane-carbonic acid (c7070) in the blood plasma of rats by high-performance liquid chromatography with mass-spectrometric detection