Sex differences in the impact of body mass index on the risk of future atrial fibrillation: Insights From the longitudinal population-based Tromso Study
Background: Atrial fibrillation (AF) prevalence is increasing, and body mass index (BMI) is a risk factor for AF. However, sex differences in the impact of BMI on AF risk have not been fully elucidated. Methods and Results: Data from the fourth survey (1994–1995) of the Tromsø Study (Norway) were us...
Published in: | Journal of the American Heart Association |
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Wiley-Blackwell
2018
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ftaustraliancuni:oai:acuresearchbank.acu.edu.au:8qywz 2023-09-05T13:23:45+02:00 Sex differences in the impact of body mass index on the risk of future atrial fibrillation: Insights From the longitudinal population-based Tromso Study Ball, Jocasta Loechen, Maja-Lisa Wilsgaard, Tom Schirmer, Henrik Hopstock, Laila Arnesdatter Morseth, Bente Mathiesen, Ellisiv Bøgeberg Njolstad, Inger Tiwari, Sweta Sharashova, Ekaterina 2018 application/pdf https://acuresearchbank.acu.edu.au/download/8d5e7c7a41a19fe502323211c7c5cf6d588a1fc16d50f7f17c2d38e0f8482bf3/1173303/OA_Ball_2018_Sex_differences_in_the_impact_of.pdf https://doi.org/10.1161/JAHA.117.008414 unknown Wiley-Blackwell https://acuresearchbank.acu.edu.au/item/8qywz/sex-differences-in-the-impact-of-body-mass-index-on-the-risk-of-future-atrial-fibrillation-insights-from-the-longitudinal-population-based-tromso-study ISSN:2047-9980 https://acuresearchbank.acu.edu.au/download/8d5e7c7a41a19fe502323211c7c5cf6d588a1fc16d50f7f17c2d38e0f8482bf3/1173303/OA_Ball_2018_Sex_differences_in_the_impact_of.pdf https://doi.org/10.1161/JAHA.117.008414 Ball, Jocasta, Loechen, Maja-Lisa, Wilsgaard, Tom, Schirmer, Henrik, Hopstock, Laila Arnesdatter, Morseth, Bente, Mathiesen, Ellisiv Bøgeberg, Njolstad, Inger, Tiwari, Sweta and Sharashova, Ekaterina. (2018). Sex differences in the impact of body mass index on the risk of future atrial fibrillation: Insights From the longitudinal population-based Tromso Study. Journal of the American Heart Association. 7(9), pp. 1 - 18. https://doi.org/10.1161/JAHA.117.008414 CC BY-NC 3.0 atrial fibrillation body mass index incidence sex differences journal-article 2018 ftaustraliancuni https://doi.org/10.1161/JAHA.117.008414 2023-08-11T14:32:46Z Background: Atrial fibrillation (AF) prevalence is increasing, and body mass index (BMI) is a risk factor for AF. However, sex differences in the impact of BMI on AF risk have not been fully elucidated. Methods and Results: Data from the fourth survey (1994–1995) of the Tromsø Study (Norway) were used to investigate the association of single-measurement BMI on future AF risk. To analyze the influence of BMI changes on AF risk, data from individuals who attended the third and fourth study surveys were used. AF diagnosis was derived from record linkage and end point adjudication. Cox regression analysis was conducted using fractional polynomials of BMI and BMI change with models adjusted for age, baseline BMI (change analyses), risk factors, comorbidities, and antihypertensive medications. Data were available for 24 799 individuals from the fourth survey (mean age, 45.5±14.2 years; 52.9% women). Over 15.7±5.5 years, 811 women (6.2%) and 918 men (7.9%) developed AF. In men, lower BMI decreased AF risk and higher BMI increased risk (hazard ratios [95% confidence intervals] for BMI 18 or 40 kg/m2 compared with 23 kg/m2 were 0.75 [0.70–0.81] and 4.42 [3.00–6.53], respectively). The same pattern was identified in women. Two surveys were attended by 14 652 individuals. In men and women, a decrease in BMI over time was associated with decreased AF risk and an increase in BMI was associated with increased AF risk. Conclusions: Within a population cohort, BMI was positively associated with AF risk. Change in BMI over time influenced AF risk in both men and women. Article in Journal/Newspaper Tromso Tromso Tromsø Australian Catholic University: ACU Research Bank Norway Tromso ENVELOPE(16.546,16.546,68.801,68.801) Tromsø Journal of the American Heart Association 7 9 |
institution |
Open Polar |
collection |
Australian Catholic University: ACU Research Bank |
op_collection_id |
ftaustraliancuni |
language |
unknown |
topic |
atrial fibrillation body mass index incidence sex differences |
spellingShingle |
atrial fibrillation body mass index incidence sex differences Ball, Jocasta Loechen, Maja-Lisa Wilsgaard, Tom Schirmer, Henrik Hopstock, Laila Arnesdatter Morseth, Bente Mathiesen, Ellisiv Bøgeberg Njolstad, Inger Tiwari, Sweta Sharashova, Ekaterina Sex differences in the impact of body mass index on the risk of future atrial fibrillation: Insights From the longitudinal population-based Tromso Study |
topic_facet |
atrial fibrillation body mass index incidence sex differences |
description |
Background: Atrial fibrillation (AF) prevalence is increasing, and body mass index (BMI) is a risk factor for AF. However, sex differences in the impact of BMI on AF risk have not been fully elucidated. Methods and Results: Data from the fourth survey (1994–1995) of the Tromsø Study (Norway) were used to investigate the association of single-measurement BMI on future AF risk. To analyze the influence of BMI changes on AF risk, data from individuals who attended the third and fourth study surveys were used. AF diagnosis was derived from record linkage and end point adjudication. Cox regression analysis was conducted using fractional polynomials of BMI and BMI change with models adjusted for age, baseline BMI (change analyses), risk factors, comorbidities, and antihypertensive medications. Data were available for 24 799 individuals from the fourth survey (mean age, 45.5±14.2 years; 52.9% women). Over 15.7±5.5 years, 811 women (6.2%) and 918 men (7.9%) developed AF. In men, lower BMI decreased AF risk and higher BMI increased risk (hazard ratios [95% confidence intervals] for BMI 18 or 40 kg/m2 compared with 23 kg/m2 were 0.75 [0.70–0.81] and 4.42 [3.00–6.53], respectively). The same pattern was identified in women. Two surveys were attended by 14 652 individuals. In men and women, a decrease in BMI over time was associated with decreased AF risk and an increase in BMI was associated with increased AF risk. Conclusions: Within a population cohort, BMI was positively associated with AF risk. Change in BMI over time influenced AF risk in both men and women. |
format |
Article in Journal/Newspaper |
author |
Ball, Jocasta Loechen, Maja-Lisa Wilsgaard, Tom Schirmer, Henrik Hopstock, Laila Arnesdatter Morseth, Bente Mathiesen, Ellisiv Bøgeberg Njolstad, Inger Tiwari, Sweta Sharashova, Ekaterina |
author_facet |
Ball, Jocasta Loechen, Maja-Lisa Wilsgaard, Tom Schirmer, Henrik Hopstock, Laila Arnesdatter Morseth, Bente Mathiesen, Ellisiv Bøgeberg Njolstad, Inger Tiwari, Sweta Sharashova, Ekaterina |
author_sort |
Ball, Jocasta |
title |
Sex differences in the impact of body mass index on the risk of future atrial fibrillation: Insights From the longitudinal population-based Tromso Study |
title_short |
Sex differences in the impact of body mass index on the risk of future atrial fibrillation: Insights From the longitudinal population-based Tromso Study |
title_full |
Sex differences in the impact of body mass index on the risk of future atrial fibrillation: Insights From the longitudinal population-based Tromso Study |
title_fullStr |
Sex differences in the impact of body mass index on the risk of future atrial fibrillation: Insights From the longitudinal population-based Tromso Study |
title_full_unstemmed |
Sex differences in the impact of body mass index on the risk of future atrial fibrillation: Insights From the longitudinal population-based Tromso Study |
title_sort |
sex differences in the impact of body mass index on the risk of future atrial fibrillation: insights from the longitudinal population-based tromso study |
publisher |
Wiley-Blackwell |
publishDate |
2018 |
url |
https://acuresearchbank.acu.edu.au/download/8d5e7c7a41a19fe502323211c7c5cf6d588a1fc16d50f7f17c2d38e0f8482bf3/1173303/OA_Ball_2018_Sex_differences_in_the_impact_of.pdf https://doi.org/10.1161/JAHA.117.008414 |
long_lat |
ENVELOPE(16.546,16.546,68.801,68.801) |
geographic |
Norway Tromso Tromsø |
geographic_facet |
Norway Tromso Tromsø |
genre |
Tromso Tromso Tromsø |
genre_facet |
Tromso Tromso Tromsø |
op_relation |
https://acuresearchbank.acu.edu.au/item/8qywz/sex-differences-in-the-impact-of-body-mass-index-on-the-risk-of-future-atrial-fibrillation-insights-from-the-longitudinal-population-based-tromso-study ISSN:2047-9980 https://acuresearchbank.acu.edu.au/download/8d5e7c7a41a19fe502323211c7c5cf6d588a1fc16d50f7f17c2d38e0f8482bf3/1173303/OA_Ball_2018_Sex_differences_in_the_impact_of.pdf https://doi.org/10.1161/JAHA.117.008414 Ball, Jocasta, Loechen, Maja-Lisa, Wilsgaard, Tom, Schirmer, Henrik, Hopstock, Laila Arnesdatter, Morseth, Bente, Mathiesen, Ellisiv Bøgeberg, Njolstad, Inger, Tiwari, Sweta and Sharashova, Ekaterina. (2018). Sex differences in the impact of body mass index on the risk of future atrial fibrillation: Insights From the longitudinal population-based Tromso Study. Journal of the American Heart Association. 7(9), pp. 1 - 18. https://doi.org/10.1161/JAHA.117.008414 |
op_rights |
CC BY-NC 3.0 |
op_doi |
https://doi.org/10.1161/JAHA.117.008414 |
container_title |
Journal of the American Heart Association |
container_volume |
7 |
container_issue |
9 |
_version_ |
1776204337571168256 |