The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study
Physical activity and overweight are associated with myocardial infarction (MI). However, their joint association with MI remains unclear. Our objective was to examine the independent and joint association between leisuretime physical activity (LTPA), body mass index (BMI) and MI. This prospective c...
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Online Access: | https://doi.org/10.1016/j.ypmed.2018.09.005 |
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ftaustraliancuni:oai:acuresearchbank.acu.edu.au:89678 2023-09-05T13:23:46+02:00 The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study Renninger, Marius Loechen, Maja-Lisa Ekelund, Ulf Hopstock, Laila Arnesdatter Jorgensen, Lone Mathiesen, Ellisiv Bøgeberg Njølstad, Inger Schirmer, Henrik Wilsgaard, Tom Morseth, Bente 2018 https://doi.org/10.1016/j.ypmed.2018.09.005 unknown Elsevier https://acuresearchbank.acu.edu.au/item/89678/the-independent-and-joint-associations-of-physical-activity-and-body-mass-index-with-myocardial-infarction-the-troms-study ISSN:0091-7435 https://doi.org/10.1016/j.ypmed.2018.09.005 Renninger, Marius, Loechen, Maja-Lisa, Ekelund, Ulf, Hopstock, Laila Arnesdatter, Jorgensen, Lone, Mathiesen, Ellisiv Bøgeberg, Njølstad, Inger, Schirmer, Henrik, Wilsgaard, Tom and Morseth, Bente. (2018). The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study. Preventive Medicine. 116, pp. 94 - 98. https://doi.org/10.1016/j.ypmed.2018.09.005 Exercise Epidemiology Myocardial infarction Obesity Overweight journal-article 2018 ftaustraliancuni https://doi.org/10.1016/j.ypmed.2018.09.005 2023-08-11T14:55:59Z Physical activity and overweight are associated with myocardial infarction (MI). However, their joint association with MI remains unclear. Our objective was to examine the independent and joint association between leisuretime physical activity (LTPA), body mass index (BMI) and MI. This prospective cohort study included 16,572 men and women (47.5% women) aged 20–54 years who took part in the second Tromsø Study. At baseline in 1979–80 LTPA was assessed by questionnaire. Data on MI was collected and adjudicated through hospital and causes of death registries between 1979 and 2013. Cox proportional hazards models were used to examine the independent and joint associations between LTPA, BMI and MI. The final sample included 16,104 individuals. During a median follow up of 34 years, 1613 incident cases of MI were recorded. Physical inactivity and elevated BMI were both independently associated with MI (p for trend 0.02 and<0.001). In joint analyses, normal weight, inactive individuals had a 20% higher risk of MI compared to their active counterparts (hazard ratio (HR) 1.20 (1.02–1.41)). The highest risk of MI was seen in obese, inactive individuals when compared to normal weight, active individuals (HR 3.20 (2.30–4.44)). The risk of MI increased with increasing BMI regardless of the activity level. HRs were lower for active compared to inactive individuals within the same BMI category. The findings suggest that LTPA and BMI are independently associated with risk of MI. LTPA seems to attenuate but not eliminate the risk of MI associated with excess bodyweight. Article in Journal/Newspaper Tromsø Australian Catholic University: ACU Research Bank Tromsø Preventive Medicine 116 94 98 |
institution |
Open Polar |
collection |
Australian Catholic University: ACU Research Bank |
op_collection_id |
ftaustraliancuni |
language |
unknown |
topic |
Exercise Epidemiology Myocardial infarction Obesity Overweight |
spellingShingle |
Exercise Epidemiology Myocardial infarction Obesity Overweight Renninger, Marius Loechen, Maja-Lisa Ekelund, Ulf Hopstock, Laila Arnesdatter Jorgensen, Lone Mathiesen, Ellisiv Bøgeberg Njølstad, Inger Schirmer, Henrik Wilsgaard, Tom Morseth, Bente The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study |
topic_facet |
Exercise Epidemiology Myocardial infarction Obesity Overweight |
description |
Physical activity and overweight are associated with myocardial infarction (MI). However, their joint association with MI remains unclear. Our objective was to examine the independent and joint association between leisuretime physical activity (LTPA), body mass index (BMI) and MI. This prospective cohort study included 16,572 men and women (47.5% women) aged 20–54 years who took part in the second Tromsø Study. At baseline in 1979–80 LTPA was assessed by questionnaire. Data on MI was collected and adjudicated through hospital and causes of death registries between 1979 and 2013. Cox proportional hazards models were used to examine the independent and joint associations between LTPA, BMI and MI. The final sample included 16,104 individuals. During a median follow up of 34 years, 1613 incident cases of MI were recorded. Physical inactivity and elevated BMI were both independently associated with MI (p for trend 0.02 and<0.001). In joint analyses, normal weight, inactive individuals had a 20% higher risk of MI compared to their active counterparts (hazard ratio (HR) 1.20 (1.02–1.41)). The highest risk of MI was seen in obese, inactive individuals when compared to normal weight, active individuals (HR 3.20 (2.30–4.44)). The risk of MI increased with increasing BMI regardless of the activity level. HRs were lower for active compared to inactive individuals within the same BMI category. The findings suggest that LTPA and BMI are independently associated with risk of MI. LTPA seems to attenuate but not eliminate the risk of MI associated with excess bodyweight. |
format |
Article in Journal/Newspaper |
author |
Renninger, Marius Loechen, Maja-Lisa Ekelund, Ulf Hopstock, Laila Arnesdatter Jorgensen, Lone Mathiesen, Ellisiv Bøgeberg Njølstad, Inger Schirmer, Henrik Wilsgaard, Tom Morseth, Bente |
author_facet |
Renninger, Marius Loechen, Maja-Lisa Ekelund, Ulf Hopstock, Laila Arnesdatter Jorgensen, Lone Mathiesen, Ellisiv Bøgeberg Njølstad, Inger Schirmer, Henrik Wilsgaard, Tom Morseth, Bente |
author_sort |
Renninger, Marius |
title |
The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study |
title_short |
The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study |
title_full |
The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study |
title_fullStr |
The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study |
title_full_unstemmed |
The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study |
title_sort |
independent and joint associations of physical activity and body mass index with myocardial infarction: the tromsø study |
publisher |
Elsevier |
publishDate |
2018 |
url |
https://doi.org/10.1016/j.ypmed.2018.09.005 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
https://acuresearchbank.acu.edu.au/item/89678/the-independent-and-joint-associations-of-physical-activity-and-body-mass-index-with-myocardial-infarction-the-troms-study ISSN:0091-7435 https://doi.org/10.1016/j.ypmed.2018.09.005 Renninger, Marius, Loechen, Maja-Lisa, Ekelund, Ulf, Hopstock, Laila Arnesdatter, Jorgensen, Lone, Mathiesen, Ellisiv Bøgeberg, Njølstad, Inger, Schirmer, Henrik, Wilsgaard, Tom and Morseth, Bente. (2018). The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study. Preventive Medicine. 116, pp. 94 - 98. https://doi.org/10.1016/j.ypmed.2018.09.005 |
op_doi |
https://doi.org/10.1016/j.ypmed.2018.09.005 |
container_title |
Preventive Medicine |
container_volume |
116 |
container_start_page |
94 |
op_container_end_page |
98 |
_version_ |
1776204353180270592 |