Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study
Background: The Rose Angina Questionnaire (RAQ) was constructed in the 1960s for assessing the population burden of angina. Studies have found that screening positivity by RAQ conferred an elevated risk of coronary heart disease (CHD). It is, however, not clear to what extent Rose angina represents...
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ftaustraliancuni:oai:acuresearchbank.acu.edu.au:880y0 2023-09-05T13:21:57+02:00 Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study Graff-Iversen, Sidsel Wilsgaard, Tom Mathiesen, Ellisiv B. Njølstad, Inger Løchen, Maja-Lisa 2014 https://doi.org/10.1136/jech-2013-203642 unknown B M J Group https://acuresearchbank.acu.edu.au/item/880y0/long-term-cardiovascular-consequences-of-rose-angina-at-age-20-54-years-29-years-follow-up-of-the-tromso-study ISSN:0143-005X https://doi.org/10.1136/jech-2013-203642 Graff-Iversen, Sidsel, Wilsgaard, Tom, Mathiesen, Ellisiv B., Njølstad, Inger and Løchen, Maja-Lisa. (2014). Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study. Journal of Epidemiology and Community Health. 68(8), pp. 754 - 759. https://doi.org/10.1136/jech-2013-203642 journal-article 2014 ftaustraliancuni https://doi.org/10.1136/jech-2013-203642 2023-08-11T15:16:07Z Background: The Rose Angina Questionnaire (RAQ) was constructed in the 1960s for assessing the population burden of angina. Studies have found that screening positivity by RAQ conferred an elevated risk of coronary heart disease (CHD). It is, however, not clear to what extent Rose angina represents early CHD in relatively young adults who are free of known CHD. If representing CHD, Rose angina is expected to carry prognostic information in addition to the risk conferred by other risk factors. Methods: The Tromsø Study is a population-based cohort study in Northern Norway. All men aged 20–54 years (n=8238) and women aged 20–49 years (n=8001), free of known cardiovascular disease (CVD), who participated in a survey 1979–1980, were followed throughout 2010 for incident myocardial infarction (MI), and for incident MI or stroke used as proxy for incident CVD. HRs were estimated using a Cox proportional hazard regression model. Results: In age-adjusted analyses, Rose angina predicted MI and CVD in both sexes. The excess risk was substantially accounted for by CVD risk factors, leaving no significantly elevated MI risk above the risk explained by these factors (adjusted HR 1.31; 95% CI 0.95 to 1.80 in men, HR 1.20; 95% CI 0.69 to 2.10 in women). A similar pattern was seen for CVD (adjusted HR 1.16; 95% CI 0.87 to 1.55 in men and 1.30; 95% CI 0.82 to 2.06 in women). Conclusions: Rose angina predicted MI and CVD in a 29-years’ follow-up of a relatively young population. Established CVD risk factors were important mediators. Article in Journal/Newspaper Northern Norway Tromso Tromso Tromsø Australian Catholic University: ACU Research Bank Norway Tromso ENVELOPE(16.546,16.546,68.801,68.801) Tromsø Journal of Epidemiology and Community Health 68 8 754 759 |
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Open Polar |
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Australian Catholic University: ACU Research Bank |
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ftaustraliancuni |
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description |
Background: The Rose Angina Questionnaire (RAQ) was constructed in the 1960s for assessing the population burden of angina. Studies have found that screening positivity by RAQ conferred an elevated risk of coronary heart disease (CHD). It is, however, not clear to what extent Rose angina represents early CHD in relatively young adults who are free of known CHD. If representing CHD, Rose angina is expected to carry prognostic information in addition to the risk conferred by other risk factors. Methods: The Tromsø Study is a population-based cohort study in Northern Norway. All men aged 20–54 years (n=8238) and women aged 20–49 years (n=8001), free of known cardiovascular disease (CVD), who participated in a survey 1979–1980, were followed throughout 2010 for incident myocardial infarction (MI), and for incident MI or stroke used as proxy for incident CVD. HRs were estimated using a Cox proportional hazard regression model. Results: In age-adjusted analyses, Rose angina predicted MI and CVD in both sexes. The excess risk was substantially accounted for by CVD risk factors, leaving no significantly elevated MI risk above the risk explained by these factors (adjusted HR 1.31; 95% CI 0.95 to 1.80 in men, HR 1.20; 95% CI 0.69 to 2.10 in women). A similar pattern was seen for CVD (adjusted HR 1.16; 95% CI 0.87 to 1.55 in men and 1.30; 95% CI 0.82 to 2.06 in women). Conclusions: Rose angina predicted MI and CVD in a 29-years’ follow-up of a relatively young population. Established CVD risk factors were important mediators. |
format |
Article in Journal/Newspaper |
author |
Graff-Iversen, Sidsel Wilsgaard, Tom Mathiesen, Ellisiv B. Njølstad, Inger Løchen, Maja-Lisa |
spellingShingle |
Graff-Iversen, Sidsel Wilsgaard, Tom Mathiesen, Ellisiv B. Njølstad, Inger Løchen, Maja-Lisa Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study |
author_facet |
Graff-Iversen, Sidsel Wilsgaard, Tom Mathiesen, Ellisiv B. Njølstad, Inger Løchen, Maja-Lisa |
author_sort |
Graff-Iversen, Sidsel |
title |
Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study |
title_short |
Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study |
title_full |
Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study |
title_fullStr |
Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study |
title_full_unstemmed |
Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study |
title_sort |
long-term cardiovascular consequences of rose angina at age 20-54 years: 29-years' follow-up of the tromso study |
publisher |
B M J Group |
publishDate |
2014 |
url |
https://doi.org/10.1136/jech-2013-203642 |
long_lat |
ENVELOPE(16.546,16.546,68.801,68.801) |
geographic |
Norway Tromso Tromsø |
geographic_facet |
Norway Tromso Tromsø |
genre |
Northern Norway Tromso Tromso Tromsø |
genre_facet |
Northern Norway Tromso Tromso Tromsø |
op_relation |
https://acuresearchbank.acu.edu.au/item/880y0/long-term-cardiovascular-consequences-of-rose-angina-at-age-20-54-years-29-years-follow-up-of-the-tromso-study ISSN:0143-005X https://doi.org/10.1136/jech-2013-203642 Graff-Iversen, Sidsel, Wilsgaard, Tom, Mathiesen, Ellisiv B., Njølstad, Inger and Løchen, Maja-Lisa. (2014). Long-term cardiovascular consequences of Rose angina at age 20-54 years: 29-years' follow-up of the Tromso Study. Journal of Epidemiology and Community Health. 68(8), pp. 754 - 759. https://doi.org/10.1136/jech-2013-203642 |
op_doi |
https://doi.org/10.1136/jech-2013-203642 |
container_title |
Journal of Epidemiology and Community Health |
container_volume |
68 |
container_issue |
8 |
container_start_page |
754 |
op_container_end_page |
759 |
_version_ |
1776202509781565440 |