Incidence and mortality of aneurysmal subarachnoid hemorrhage in two Norwegian cohorts, 1984-2007
Objective: The incidence of aneurysmal subarachnoid hemorrhage (aSAH) ranges from 4 to 10 per 100,000 person-years in most countries, and 30-day case fatality is high. The aim of this study was to estimate the incidence and case fatality of aSAH and to assess preictal predictors of survival in 2 lar...
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2011
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Online Access: | https://doi.org/10.1212/WNL.0b013e3182377de3 |
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ftaustraliancuni:oai:acuresearchbank.acu.edu.au:87919 2023-09-05T13:23:47+02:00 Incidence and mortality of aneurysmal subarachnoid hemorrhage in two Norwegian cohorts, 1984-2007 Sandvei, M. S. Mathiesen, E. B. Vatten, L. J. Müller, T. B. Lindekleiv, H. Ingebrigtsen, T. Njølstad, I. Wilsgaard, Tom Løchen, Maja-Lisa Vik, A. Romundstad, P. R. 2011 https://doi.org/10.1212/WNL.0b013e3182377de3 unknown Lippincott Williams & Wilkins https://acuresearchbank.acu.edu.au/item/87919/incidence-and-mortality-of-aneurysmal-subarachnoid-hemorrhage-in-two-norwegian-cohorts-1984-2007 ISSN:0028-3878 https://doi.org/10.1212/WNL.0b013e3182377de3 Sandvei, M. S., Mathiesen, E. B., Vatten, L. J., Müller, T. B., Lindekleiv, H., Ingebrigtsen, T., Njølstad, I., Wilsgaard, Tom, Løchen, Maja-Lisa, Vik, A. and Romundstad, P. R. (2011). Incidence and mortality of aneurysmal subarachnoid hemorrhage in two Norwegian cohorts, 1984-2007. Neurology. 77(20), pp. 1833 - 1839. https://doi.org/10.1212/WNL.0b013e3182377de3 journal-article 2011 ftaustraliancuni https://doi.org/10.1212/WNL.0b013e3182377de3 2023-08-11T15:23:12Z Objective: The incidence of aneurysmal subarachnoid hemorrhage (aSAH) ranges from 4 to 10 per 100,000 person-years in most countries, and 30-day case fatality is high. The aim of this study was to estimate the incidence and case fatality of aSAH and to assess preictal predictors of survival in 2 large Norwegian population-based cohort studies. Methods: A total of 94,976 adults (≥20 years) in the Nord-Trøndelag Health Study and 31,753 participants (aged ≥20 years) in the Tromsø Study were included. During follow-up, aSAHs were identified, incidence rates were estimated, and predictors of survival were assessed using Cox and Poisson regression analysis. Results: A total of 214 patients with aSAH were identified during 2,077,927 person-years of follow-up from 1984 to 2007. The incidence rate was 10.3 per 100,000 person-years: 13.3 for women and 7.1 for men. The incidence increased by 2% (95% confidence interval [CI] 0–4) per 5-year time period. Case fatality at 3, 7, and 30 days was 20%, 24%, and 36%. Thirty-day case fatality remained stable during follow-up (odds ratio 1.01, 95% CI 0.97–1.06 per year). Never smokers had poorer survival after aSAH than current and former smokers combined (hazard ratio 1.6, 95% CI 0.9–2.9). Conclusions: The slight increase in incidence of aSAH over time may be explained by differences in diagnostic procedures. Case fatality remained stable during 23 years of follow-up. Article in Journal/Newspaper Tromsø Australian Catholic University: ACU Research Bank Tromsø Neurology 77 20 1833 1839 |
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Australian Catholic University: ACU Research Bank |
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ftaustraliancuni |
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description |
Objective: The incidence of aneurysmal subarachnoid hemorrhage (aSAH) ranges from 4 to 10 per 100,000 person-years in most countries, and 30-day case fatality is high. The aim of this study was to estimate the incidence and case fatality of aSAH and to assess preictal predictors of survival in 2 large Norwegian population-based cohort studies. Methods: A total of 94,976 adults (≥20 years) in the Nord-Trøndelag Health Study and 31,753 participants (aged ≥20 years) in the Tromsø Study were included. During follow-up, aSAHs were identified, incidence rates were estimated, and predictors of survival were assessed using Cox and Poisson regression analysis. Results: A total of 214 patients with aSAH were identified during 2,077,927 person-years of follow-up from 1984 to 2007. The incidence rate was 10.3 per 100,000 person-years: 13.3 for women and 7.1 for men. The incidence increased by 2% (95% confidence interval [CI] 0–4) per 5-year time period. Case fatality at 3, 7, and 30 days was 20%, 24%, and 36%. Thirty-day case fatality remained stable during follow-up (odds ratio 1.01, 95% CI 0.97–1.06 per year). Never smokers had poorer survival after aSAH than current and former smokers combined (hazard ratio 1.6, 95% CI 0.9–2.9). Conclusions: The slight increase in incidence of aSAH over time may be explained by differences in diagnostic procedures. Case fatality remained stable during 23 years of follow-up. |
format |
Article in Journal/Newspaper |
author |
Sandvei, M. S. Mathiesen, E. B. Vatten, L. J. Müller, T. B. Lindekleiv, H. Ingebrigtsen, T. Njølstad, I. Wilsgaard, Tom Løchen, Maja-Lisa Vik, A. Romundstad, P. R. |
spellingShingle |
Sandvei, M. S. Mathiesen, E. B. Vatten, L. J. Müller, T. B. Lindekleiv, H. Ingebrigtsen, T. Njølstad, I. Wilsgaard, Tom Løchen, Maja-Lisa Vik, A. Romundstad, P. R. Incidence and mortality of aneurysmal subarachnoid hemorrhage in two Norwegian cohorts, 1984-2007 |
author_facet |
Sandvei, M. S. Mathiesen, E. B. Vatten, L. J. Müller, T. B. Lindekleiv, H. Ingebrigtsen, T. Njølstad, I. Wilsgaard, Tom Løchen, Maja-Lisa Vik, A. Romundstad, P. R. |
author_sort |
Sandvei, M. S. |
title |
Incidence and mortality of aneurysmal subarachnoid hemorrhage in two Norwegian cohorts, 1984-2007 |
title_short |
Incidence and mortality of aneurysmal subarachnoid hemorrhage in two Norwegian cohorts, 1984-2007 |
title_full |
Incidence and mortality of aneurysmal subarachnoid hemorrhage in two Norwegian cohorts, 1984-2007 |
title_fullStr |
Incidence and mortality of aneurysmal subarachnoid hemorrhage in two Norwegian cohorts, 1984-2007 |
title_full_unstemmed |
Incidence and mortality of aneurysmal subarachnoid hemorrhage in two Norwegian cohorts, 1984-2007 |
title_sort |
incidence and mortality of aneurysmal subarachnoid hemorrhage in two norwegian cohorts, 1984-2007 |
publisher |
Lippincott Williams & Wilkins |
publishDate |
2011 |
url |
https://doi.org/10.1212/WNL.0b013e3182377de3 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
https://acuresearchbank.acu.edu.au/item/87919/incidence-and-mortality-of-aneurysmal-subarachnoid-hemorrhage-in-two-norwegian-cohorts-1984-2007 ISSN:0028-3878 https://doi.org/10.1212/WNL.0b013e3182377de3 Sandvei, M. S., Mathiesen, E. B., Vatten, L. J., Müller, T. B., Lindekleiv, H., Ingebrigtsen, T., Njølstad, I., Wilsgaard, Tom, Løchen, Maja-Lisa, Vik, A. and Romundstad, P. R. (2011). Incidence and mortality of aneurysmal subarachnoid hemorrhage in two Norwegian cohorts, 1984-2007. Neurology. 77(20), pp. 1833 - 1839. https://doi.org/10.1212/WNL.0b013e3182377de3 |
op_doi |
https://doi.org/10.1212/WNL.0b013e3182377de3 |
container_title |
Neurology |
container_volume |
77 |
container_issue |
20 |
container_start_page |
1833 |
op_container_end_page |
1839 |
_version_ |
1776204361982017536 |