Secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the Tromso Study 1994-2016
Background: Secondary prevention guidelines after myocardial infarction (MI) are gender neutral, but underutilisation of treatment in women has been reported. Design: We investigated the change in total and low-density lipoprotein (LDL) cholesterol levels and lipid-lowering drug (LLD) use after firs...
Published in: | European Journal of Cardiovascular Nursing |
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Sage Publications Ltd.
2018
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Online Access: | https://doi.org/10.1177/1474515118762541 |
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ftaustraliancuni:oai:acuresearchbank.acu.edu.au:85x2z 2023-09-05T13:23:45+02:00 Secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the Tromso Study 1994-2016 Hopstock, Laila Arnesdatter Eggen, Anne Elise Loechen, Maja-Lisa Mathiesen, Ellisiv Bøgeberg Njolstad, Inger Wilsgaard, Tom 2018 https://doi.org/10.1177/1474515118762541 unknown Sage Publications Ltd. https://acuresearchbank.acu.edu.au/item/85x2z/secondary-prevention-care-and-effect-total-and-low-density-lipoprotein-cholesterol-levels-and-lipid-lowering-drug-use-in-women-and-men-after-incident-myocardial-infarction-the-tromso-study-1994-2016 ISSN:1474-5151 https://doi.org/10.1177/1474515118762541 Hopstock, Laila Arnesdatter, Eggen, Anne Elise, Loechen, Maja-Lisa, Mathiesen, Ellisiv Bøgeberg, Njolstad, Inger and Wilsgaard, Tom. (2018). Secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the Tromso Study 1994-2016. European Journal of Cardiovascular Nursing. 17(6), pp. 563 - 570. https://doi.org/10.1177/1474515118762541 Anticholesterolaemic agents cohort studies gender differences lipids myocardial infarction secondary prevention care journal-article 2018 ftaustraliancuni https://doi.org/10.1177/1474515118762541 2023-08-11T15:48:35Z Background: Secondary prevention guidelines after myocardial infarction (MI) are gender neutral, but underutilisation of treatment in women has been reported. Design: We investigated the change in total and low-density lipoprotein (LDL) cholesterol levels and lipid-lowering drug (LLD) use after first-ever MI in a population-based study. Methods: We followed 10,005 participants (54% women) attending the Tromsø Study 1994–1995 and 8483 participants (55% women) attending the Tromsø Study 2007–2008 for first-ever MI up to their participation in 2007–2008 and 2015–2016, respectively. We used linear and logistic regression models to investigate sex differences in change in lipid levels. Results: A total of 395 (MI cohort I) and 132 participants (MI cohort II) had a first-ever MI during 1994–2008 and 2007–2013, respectively. Mean change in total cholesterol was −2.34 mmol/L (SD 1.15) in MI cohort I, and in LDL cholesterol was −1.63 mmol/L (SD 1.12) in MI cohort II. Men had a larger decrease in lipid levels compared to women: the linear regression coefficient for change was −0.33 (95% confidence interval [CI] −0.51 to −0.14) for total cholesterol and −0.21 (95% CI −0.37 to −0.04) for LDL cholesterol, adjusted for baseline lipid value, age and cohort. Men had 73% higher odds (95% CI 1.15−2.61) of treatment target achievement compared to women, adjusted for baseline lipid value, age and cohort. LLD use was reported in 85% of women and 92% of men in MI cohort I, and 80% in women and 89% in men in MI cohort II. Conclusions: Compared to men, women had significantly less decrease in lipid levels after MI, and a smaller proportion of women achieved the treatment target. Article in Journal/Newspaper Tromso Tromso Tromsø Australian Catholic University: ACU Research Bank Tromso ENVELOPE(16.546,16.546,68.801,68.801) Tromsø European Journal of Cardiovascular Nursing 17 6 563 570 |
institution |
Open Polar |
collection |
Australian Catholic University: ACU Research Bank |
op_collection_id |
ftaustraliancuni |
language |
unknown |
topic |
Anticholesterolaemic agents cohort studies gender differences lipids myocardial infarction secondary prevention care |
spellingShingle |
Anticholesterolaemic agents cohort studies gender differences lipids myocardial infarction secondary prevention care Hopstock, Laila Arnesdatter Eggen, Anne Elise Loechen, Maja-Lisa Mathiesen, Ellisiv Bøgeberg Njolstad, Inger Wilsgaard, Tom Secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the Tromso Study 1994-2016 |
topic_facet |
Anticholesterolaemic agents cohort studies gender differences lipids myocardial infarction secondary prevention care |
description |
Background: Secondary prevention guidelines after myocardial infarction (MI) are gender neutral, but underutilisation of treatment in women has been reported. Design: We investigated the change in total and low-density lipoprotein (LDL) cholesterol levels and lipid-lowering drug (LLD) use after first-ever MI in a population-based study. Methods: We followed 10,005 participants (54% women) attending the Tromsø Study 1994–1995 and 8483 participants (55% women) attending the Tromsø Study 2007–2008 for first-ever MI up to their participation in 2007–2008 and 2015–2016, respectively. We used linear and logistic regression models to investigate sex differences in change in lipid levels. Results: A total of 395 (MI cohort I) and 132 participants (MI cohort II) had a first-ever MI during 1994–2008 and 2007–2013, respectively. Mean change in total cholesterol was −2.34 mmol/L (SD 1.15) in MI cohort I, and in LDL cholesterol was −1.63 mmol/L (SD 1.12) in MI cohort II. Men had a larger decrease in lipid levels compared to women: the linear regression coefficient for change was −0.33 (95% confidence interval [CI] −0.51 to −0.14) for total cholesterol and −0.21 (95% CI −0.37 to −0.04) for LDL cholesterol, adjusted for baseline lipid value, age and cohort. Men had 73% higher odds (95% CI 1.15−2.61) of treatment target achievement compared to women, adjusted for baseline lipid value, age and cohort. LLD use was reported in 85% of women and 92% of men in MI cohort I, and 80% in women and 89% in men in MI cohort II. Conclusions: Compared to men, women had significantly less decrease in lipid levels after MI, and a smaller proportion of women achieved the treatment target. |
format |
Article in Journal/Newspaper |
author |
Hopstock, Laila Arnesdatter Eggen, Anne Elise Loechen, Maja-Lisa Mathiesen, Ellisiv Bøgeberg Njolstad, Inger Wilsgaard, Tom |
author_facet |
Hopstock, Laila Arnesdatter Eggen, Anne Elise Loechen, Maja-Lisa Mathiesen, Ellisiv Bøgeberg Njolstad, Inger Wilsgaard, Tom |
author_sort |
Hopstock, Laila Arnesdatter |
title |
Secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the Tromso Study 1994-2016 |
title_short |
Secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the Tromso Study 1994-2016 |
title_full |
Secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the Tromso Study 1994-2016 |
title_fullStr |
Secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the Tromso Study 1994-2016 |
title_full_unstemmed |
Secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the Tromso Study 1994-2016 |
title_sort |
secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the tromso study 1994-2016 |
publisher |
Sage Publications Ltd. |
publishDate |
2018 |
url |
https://doi.org/10.1177/1474515118762541 |
long_lat |
ENVELOPE(16.546,16.546,68.801,68.801) |
geographic |
Tromso Tromsø |
geographic_facet |
Tromso Tromsø |
genre |
Tromso Tromso Tromsø |
genre_facet |
Tromso Tromso Tromsø |
op_relation |
https://acuresearchbank.acu.edu.au/item/85x2z/secondary-prevention-care-and-effect-total-and-low-density-lipoprotein-cholesterol-levels-and-lipid-lowering-drug-use-in-women-and-men-after-incident-myocardial-infarction-the-tromso-study-1994-2016 ISSN:1474-5151 https://doi.org/10.1177/1474515118762541 Hopstock, Laila Arnesdatter, Eggen, Anne Elise, Loechen, Maja-Lisa, Mathiesen, Ellisiv Bøgeberg, Njolstad, Inger and Wilsgaard, Tom. (2018). Secondary prevention care and effect: total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction - the Tromso Study 1994-2016. European Journal of Cardiovascular Nursing. 17(6), pp. 563 - 570. https://doi.org/10.1177/1474515118762541 |
op_doi |
https://doi.org/10.1177/1474515118762541 |
container_title |
European Journal of Cardiovascular Nursing |
container_volume |
17 |
container_issue |
6 |
container_start_page |
563 |
op_container_end_page |
570 |
_version_ |
1776204338951094272 |