Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms
Purpose Blastomycosis is a serious fungal infection contracted by inhalation of Blastomyces spores from the environment. Case occurrence in dogs in Vilas County, Wisconsin, has been associated with antecedent weather. We aimed to explore the effects of weather on the occurrence of human pulmonary bl...
Published in: | Journal of Patient-Centered Research and Reviews |
---|---|
Main Authors: | , , |
Format: | Text |
Language: | unknown |
Published: |
Advocate Aurora Health Institutional Repository
2015
|
Subjects: | |
Online Access: | https://institutionalrepository.aah.org/jpcrr/vol2/iss1/5 https://doi.org/10.17294/2330-0698.1050 https://institutionalrepository.aah.org/context/jpcrr/article/1050/viewcontent/baumgardner_RESEARCH_revision.pdf |
id |
ftaurorahc:oai:institutionalrepository.aah.org:jpcrr-1050 |
---|---|
record_format |
openpolar |
spelling |
ftaurorahc:oai:institutionalrepository.aah.org:jpcrr-1050 2023-07-23T04:20:48+02:00 Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms Baumgardner, Dennis J Bernhard, Kiley A. Egan, Gina 2015-01-30T08:00:00Z application/pdf https://institutionalrepository.aah.org/jpcrr/vol2/iss1/5 https://doi.org/10.17294/2330-0698.1050 https://institutionalrepository.aah.org/context/jpcrr/article/1050/viewcontent/baumgardner_RESEARCH_revision.pdf unknown Advocate Aurora Health Institutional Repository https://institutionalrepository.aah.org/jpcrr/vol2/iss1/5 doi:10.17294/2330-0698.1050 https://institutionalrepository.aah.org/context/jpcrr/article/1050/viewcontent/baumgardner_RESEARCH_revision.pdf Journal of Patient-Centered Research and Reviews Blastomyces dermatitidis fungal ecology mycoses weather Fungi Infectious Disease text 2015 ftaurorahc https://doi.org/10.17294/2330-0698.1050 2023-07-05T20:12:36Z Purpose Blastomycosis is a serious fungal infection contracted by inhalation of Blastomyces spores from the environment. Case occurrence in dogs in Vilas County, Wisconsin, has been associated with antecedent weather. We aimed to explore the effects of weather on the occurrence of human pulmonary blastomycosis in this area, and update exposure factors and symptoms since last published reports. Methods Mandatory case reports were reviewed. Chi-square test was used for categorical data of exposures, comparing 1979–1996 (n=101) versus 1997–June 2013 (n=95). Linear regression was used to model local weather data (available 1990–2013; n=126); Southern Oscillation Index (SOI), North Atlantic Oscillation Index (NAOI), and Wisconsin River water discharge (WRD) from the adjacent county (all available for 1984–2013; n=174); and case counts of known onset by warm (April–September) and cold (October–March) 6-month periods. Results Distribution of pulmonary blastomycosis cases did not vary by season. Environmental exposures for the 1997–June 2013 group (mean age 45, 59% male) were: residence(76%), excavation (42%) and gardening (31%), all similar to the 1979–1996 group. Fishing (23% vs. 37%; P=0.09) and hunting (15% vs. 26%; P=0.13) exposures were less common in 1997–June 2013, but not significantly different. Overall, 69% of cases recalled some prior soil-disturbing activities. Considering the 6-month warm/cold periods, 19% of variation is explained by a direct relationship with total precipitation from two periods prior (P=0.005). There was no association of case occurrence with SOI, NAOI or WRD. Estimated annual incidence of blastomycosis for 1997–June 2013 was 27/100,000 compared with 44/100,000 for 1984–1996. Several symptoms were significantly less frequent in 2002–June 2013 compared to earlier years. Conclusions As with dogs, human pulmonary blastomycosis occurrence is partially determined by antecedent precipitation. It is unclear if recent lower incidence rates are due to less opportunity for exposure to weather, ... Text North Atlantic North Atlantic oscillation Aurora Health Care Digital Repository Soi ENVELOPE(30.704,30.704,66.481,66.481) Journal of Patient-Centered Research and Reviews 2 1 25 33 |
institution |
Open Polar |
collection |
Aurora Health Care Digital Repository |
op_collection_id |
ftaurorahc |
language |
unknown |
topic |
Blastomyces dermatitidis fungal ecology mycoses weather Fungi Infectious Disease |
spellingShingle |
Blastomyces dermatitidis fungal ecology mycoses weather Fungi Infectious Disease Baumgardner, Dennis J Bernhard, Kiley A. Egan, Gina Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
topic_facet |
Blastomyces dermatitidis fungal ecology mycoses weather Fungi Infectious Disease |
description |
Purpose Blastomycosis is a serious fungal infection contracted by inhalation of Blastomyces spores from the environment. Case occurrence in dogs in Vilas County, Wisconsin, has been associated with antecedent weather. We aimed to explore the effects of weather on the occurrence of human pulmonary blastomycosis in this area, and update exposure factors and symptoms since last published reports. Methods Mandatory case reports were reviewed. Chi-square test was used for categorical data of exposures, comparing 1979–1996 (n=101) versus 1997–June 2013 (n=95). Linear regression was used to model local weather data (available 1990–2013; n=126); Southern Oscillation Index (SOI), North Atlantic Oscillation Index (NAOI), and Wisconsin River water discharge (WRD) from the adjacent county (all available for 1984–2013; n=174); and case counts of known onset by warm (April–September) and cold (October–March) 6-month periods. Results Distribution of pulmonary blastomycosis cases did not vary by season. Environmental exposures for the 1997–June 2013 group (mean age 45, 59% male) were: residence(76%), excavation (42%) and gardening (31%), all similar to the 1979–1996 group. Fishing (23% vs. 37%; P=0.09) and hunting (15% vs. 26%; P=0.13) exposures were less common in 1997–June 2013, but not significantly different. Overall, 69% of cases recalled some prior soil-disturbing activities. Considering the 6-month warm/cold periods, 19% of variation is explained by a direct relationship with total precipitation from two periods prior (P=0.005). There was no association of case occurrence with SOI, NAOI or WRD. Estimated annual incidence of blastomycosis for 1997–June 2013 was 27/100,000 compared with 44/100,000 for 1984–1996. Several symptoms were significantly less frequent in 2002–June 2013 compared to earlier years. Conclusions As with dogs, human pulmonary blastomycosis occurrence is partially determined by antecedent precipitation. It is unclear if recent lower incidence rates are due to less opportunity for exposure to weather, ... |
format |
Text |
author |
Baumgardner, Dennis J Bernhard, Kiley A. Egan, Gina |
author_facet |
Baumgardner, Dennis J Bernhard, Kiley A. Egan, Gina |
author_sort |
Baumgardner, Dennis J |
title |
Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
title_short |
Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
title_full |
Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
title_fullStr |
Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
title_full_unstemmed |
Pulmonary Blastomycosis in Vilas County, Wisconsin: Weather, Exposures and Symptoms |
title_sort |
pulmonary blastomycosis in vilas county, wisconsin: weather, exposures and symptoms |
publisher |
Advocate Aurora Health Institutional Repository |
publishDate |
2015 |
url |
https://institutionalrepository.aah.org/jpcrr/vol2/iss1/5 https://doi.org/10.17294/2330-0698.1050 https://institutionalrepository.aah.org/context/jpcrr/article/1050/viewcontent/baumgardner_RESEARCH_revision.pdf |
long_lat |
ENVELOPE(30.704,30.704,66.481,66.481) |
geographic |
Soi |
geographic_facet |
Soi |
genre |
North Atlantic North Atlantic oscillation |
genre_facet |
North Atlantic North Atlantic oscillation |
op_source |
Journal of Patient-Centered Research and Reviews |
op_relation |
https://institutionalrepository.aah.org/jpcrr/vol2/iss1/5 doi:10.17294/2330-0698.1050 https://institutionalrepository.aah.org/context/jpcrr/article/1050/viewcontent/baumgardner_RESEARCH_revision.pdf |
op_doi |
https://doi.org/10.17294/2330-0698.1050 |
container_title |
Journal of Patient-Centered Research and Reviews |
container_volume |
2 |
container_issue |
1 |
container_start_page |
25 |
op_container_end_page |
33 |
_version_ |
1772185532689809408 |