Biobehavioral measures as outcomes: a cautionary tale
This article discusses the use of biobehavioral measures as outcomes for health care intervention studies. Effect size (ES) values for salivary cortisol and observation-based measures of pain and agitation were examined. Effects pre to post treatment were assessed separately for nursing home residen...
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ftaurorahc:oai:institutionalrepository.aah.org:behav-1004 2023-07-23T04:18:25+02:00 Biobehavioral measures as outcomes: a cautionary tale Kovach, Christine R Woods, Diana Lynn Devine, Elizabeth C Logan, Brent R Raff, Hershel 2014-03-01T08:00:00Z https://institutionalrepository.aah.org/behav/5 https://doi.org/10.3928/19404921-20131018-01 unknown Advocate Aurora Health Institutional Repository https://institutionalrepository.aah.org/behav/5 doi:doi:10.3928/19404921-20131018-01 Behavioral Health Aged 80 and over Biological Markers Dementia Female Humans Hydrocortisone Intervention Studies Nursing Homes Observation Outcome Assessment (Health Care) Pain Management Pain Measurement Psychomotor Agitation Advocate Aurora Research Institute text 2014 ftaurorahc https://doi.org/10.3928/19404921-20131018-01 2023-07-05T20:11:59Z This article discusses the use of biobehavioral measures as outcomes for health care intervention studies. Effect size (ES) values for salivary cortisol and observation-based measures of pain and agitation were examined. Effects pre to post treatment were assessed separately for nursing home residents with and without acute psychotic symptoms. This study revealed large positive effects on both pain and agitation measures in the group with acute psychotic symptoms and small-to-medium positive effects on these same measures in the group without acute psychotic symptoms. In both of these groups, the ES values were not consistently positive on the cortisol measures. Prior to determining whether a measure can be used to estimate minimum clinically important differences, it is essential to consider if the biomarker will be responsive to therapy in the populations and contexts being studied. Text Aurora Research Institute Aurora Health Care Digital Repository Research in Gerontological Nursing 7 2 56 65 |
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Aurora Health Care Digital Repository |
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Aged 80 and over Biological Markers Dementia Female Humans Hydrocortisone Intervention Studies Nursing Homes Observation Outcome Assessment (Health Care) Pain Management Pain Measurement Psychomotor Agitation Advocate Aurora Research Institute |
spellingShingle |
Aged 80 and over Biological Markers Dementia Female Humans Hydrocortisone Intervention Studies Nursing Homes Observation Outcome Assessment (Health Care) Pain Management Pain Measurement Psychomotor Agitation Advocate Aurora Research Institute Kovach, Christine R Woods, Diana Lynn Devine, Elizabeth C Logan, Brent R Raff, Hershel Biobehavioral measures as outcomes: a cautionary tale |
topic_facet |
Aged 80 and over Biological Markers Dementia Female Humans Hydrocortisone Intervention Studies Nursing Homes Observation Outcome Assessment (Health Care) Pain Management Pain Measurement Psychomotor Agitation Advocate Aurora Research Institute |
description |
This article discusses the use of biobehavioral measures as outcomes for health care intervention studies. Effect size (ES) values for salivary cortisol and observation-based measures of pain and agitation were examined. Effects pre to post treatment were assessed separately for nursing home residents with and without acute psychotic symptoms. This study revealed large positive effects on both pain and agitation measures in the group with acute psychotic symptoms and small-to-medium positive effects on these same measures in the group without acute psychotic symptoms. In both of these groups, the ES values were not consistently positive on the cortisol measures. Prior to determining whether a measure can be used to estimate minimum clinically important differences, it is essential to consider if the biomarker will be responsive to therapy in the populations and contexts being studied. |
format |
Text |
author |
Kovach, Christine R Woods, Diana Lynn Devine, Elizabeth C Logan, Brent R Raff, Hershel |
author_facet |
Kovach, Christine R Woods, Diana Lynn Devine, Elizabeth C Logan, Brent R Raff, Hershel |
author_sort |
Kovach, Christine R |
title |
Biobehavioral measures as outcomes: a cautionary tale |
title_short |
Biobehavioral measures as outcomes: a cautionary tale |
title_full |
Biobehavioral measures as outcomes: a cautionary tale |
title_fullStr |
Biobehavioral measures as outcomes: a cautionary tale |
title_full_unstemmed |
Biobehavioral measures as outcomes: a cautionary tale |
title_sort |
biobehavioral measures as outcomes: a cautionary tale |
publisher |
Advocate Aurora Health Institutional Repository |
publishDate |
2014 |
url |
https://institutionalrepository.aah.org/behav/5 https://doi.org/10.3928/19404921-20131018-01 |
genre |
Aurora Research Institute |
genre_facet |
Aurora Research Institute |
op_source |
Behavioral Health |
op_relation |
https://institutionalrepository.aah.org/behav/5 doi:doi:10.3928/19404921-20131018-01 |
op_doi |
https://doi.org/10.3928/19404921-20131018-01 |
container_title |
Research in Gerontological Nursing |
container_volume |
7 |
container_issue |
2 |
container_start_page |
56 |
op_container_end_page |
65 |
_version_ |
1772180742514671616 |