Evaluation of the biological toxicity of fluorine in Antarctic krill
Antarctic krill is a potentially nutritious food source for humans, but fluorine (F) toxicity is a matter of concern. To evaluate the toxicity of F in Antarctic krill, 30 Wistar rats were divided into three groups with different dietary regimens: a control group, a krill treatment group (150 mg·kg−1...
Main Authors: | , , , , , , , |
---|---|
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Polar Research Institute of China - PRIC
2014
|
Subjects: | |
Online Access: | http://library.arcticportal.org/2519/ http://library.arcticportal.org/2519/1/A20140106.pdf |
id |
ftarcticportal:oai:generic.eprints.org:2519 |
---|---|
record_format |
openpolar |
spelling |
ftarcticportal:oai:generic.eprints.org:2519 2023-11-05T03:31:02+01:00 Evaluation of the biological toxicity of fluorine in Antarctic krill Ling, Zhang Xiaoqi, Lu Zhangmin, Wang Liqiang, Qin Zhiqin, Lin Linxi, Yuan Wen, Zhang Xuebin, Yin 2014-03 application/pdf http://library.arcticportal.org/2519/ http://library.arcticportal.org/2519/1/A20140106.pdf en eng Polar Research Institute of China - PRIC http://library.arcticportal.org/2519/1/A20140106.pdf Ling, Zhang and Xiaoqi, Lu and Zhangmin, Wang and Liqiang, Qin and Zhiqin, Lin and Linxi, Yuan and Wen, Zhang and Xuebin, Yin (2014) Evaluation of the biological toxicity of fluorine in Antarctic krill. Advances in Polar Science, 25 (1). pp. 38-45. Fauna Article PeerReviewed 2014 ftarcticportal 2023-10-11T22:54:25Z Antarctic krill is a potentially nutritious food source for humans, but fluorine (F) toxicity is a matter of concern. To evaluate the toxicity of F in Antarctic krill, 30 Wistar rats were divided into three groups with different dietary regimens: a control group, a krill treatment group (150 mg·kg−1 F), and a sodium fluoride (NaF) treatment group (150 mg·kg−1 F). After three months, F concentrations in feces, plasma, and bone were determined, and the degree of dental and skeletal fluorosis was assessed. The F concentrations in plasma and bone from the krill treatment group were 0.167 0±0.020 4 mg.L−1 and 2 709.8±301.9 mg·kg−1, respectively, compared with 0.043 8±0.005 5 mg·L−1 and 442.4±60.7 mg·kg−1, respectively, in samples from the control group. Concentrations of F in plasma and bone in the krill treatment group were higher than in the control group, but lower than in the NaF treatment group. The degree of dental fluorosis in the krill treatment group was moderate, compared with severe in the NaF treatment group and normal in the control group. The degree of skeletal fluorosis did not change significantly in any group. These results showed that the toxicity of F in Antarctic krill was lower than for an equivalent concentration of F in NaF, but it was toxic for rats consuming krill in large quantities. To conclude, we discuss possible reasons for the reduced toxicity of F in Antarctic krill. The present study provides a direct toxicological reference for the consideration of Antarctic krill for human consumption. Article in Journal/Newspaper Advances in Polar Science Antarc* Antarctic Antarctic Krill Polar Science Polar Science Arctic Portal Library |
institution |
Open Polar |
collection |
Arctic Portal Library |
op_collection_id |
ftarcticportal |
language |
English |
topic |
Fauna |
spellingShingle |
Fauna Ling, Zhang Xiaoqi, Lu Zhangmin, Wang Liqiang, Qin Zhiqin, Lin Linxi, Yuan Wen, Zhang Xuebin, Yin Evaluation of the biological toxicity of fluorine in Antarctic krill |
topic_facet |
Fauna |
description |
Antarctic krill is a potentially nutritious food source for humans, but fluorine (F) toxicity is a matter of concern. To evaluate the toxicity of F in Antarctic krill, 30 Wistar rats were divided into three groups with different dietary regimens: a control group, a krill treatment group (150 mg·kg−1 F), and a sodium fluoride (NaF) treatment group (150 mg·kg−1 F). After three months, F concentrations in feces, plasma, and bone were determined, and the degree of dental and skeletal fluorosis was assessed. The F concentrations in plasma and bone from the krill treatment group were 0.167 0±0.020 4 mg.L−1 and 2 709.8±301.9 mg·kg−1, respectively, compared with 0.043 8±0.005 5 mg·L−1 and 442.4±60.7 mg·kg−1, respectively, in samples from the control group. Concentrations of F in plasma and bone in the krill treatment group were higher than in the control group, but lower than in the NaF treatment group. The degree of dental fluorosis in the krill treatment group was moderate, compared with severe in the NaF treatment group and normal in the control group. The degree of skeletal fluorosis did not change significantly in any group. These results showed that the toxicity of F in Antarctic krill was lower than for an equivalent concentration of F in NaF, but it was toxic for rats consuming krill in large quantities. To conclude, we discuss possible reasons for the reduced toxicity of F in Antarctic krill. The present study provides a direct toxicological reference for the consideration of Antarctic krill for human consumption. |
format |
Article in Journal/Newspaper |
author |
Ling, Zhang Xiaoqi, Lu Zhangmin, Wang Liqiang, Qin Zhiqin, Lin Linxi, Yuan Wen, Zhang Xuebin, Yin |
author_facet |
Ling, Zhang Xiaoqi, Lu Zhangmin, Wang Liqiang, Qin Zhiqin, Lin Linxi, Yuan Wen, Zhang Xuebin, Yin |
author_sort |
Ling, Zhang |
title |
Evaluation of the biological toxicity of fluorine in Antarctic krill |
title_short |
Evaluation of the biological toxicity of fluorine in Antarctic krill |
title_full |
Evaluation of the biological toxicity of fluorine in Antarctic krill |
title_fullStr |
Evaluation of the biological toxicity of fluorine in Antarctic krill |
title_full_unstemmed |
Evaluation of the biological toxicity of fluorine in Antarctic krill |
title_sort |
evaluation of the biological toxicity of fluorine in antarctic krill |
publisher |
Polar Research Institute of China - PRIC |
publishDate |
2014 |
url |
http://library.arcticportal.org/2519/ http://library.arcticportal.org/2519/1/A20140106.pdf |
genre |
Advances in Polar Science Antarc* Antarctic Antarctic Krill Polar Science Polar Science |
genre_facet |
Advances in Polar Science Antarc* Antarctic Antarctic Krill Polar Science Polar Science |
op_relation |
http://library.arcticportal.org/2519/1/A20140106.pdf Ling, Zhang and Xiaoqi, Lu and Zhangmin, Wang and Liqiang, Qin and Zhiqin, Lin and Linxi, Yuan and Wen, Zhang and Xuebin, Yin (2014) Evaluation of the biological toxicity of fluorine in Antarctic krill. Advances in Polar Science, 25 (1). pp. 38-45. |
_version_ |
1781696826600062976 |