Development of Mercury Analysis by NanoSIMS for the Localization of Mercury–Selenium Particles in Whale Liver
International audience Nanoscale secondary ion mass spectrometry (NanoSIMS) is a dynamic SIMS technique, which offers high spatial resolution allowing the mapping of chemical elements at the nanometer scale combined with high sensitivity. However, SIMS for mercury analysis is a challenging issue due...
Published in: | Analytical Chemistry |
---|---|
Main Authors: | , , , , , , , |
Other Authors: | , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
HAL CCSD
2021
|
Subjects: | |
Online Access: | https://hal.science/hal-03454238 https://hal.science/hal-03454238/document https://hal.science/hal-03454238/file/NanoSIMS_mercury.pdf https://doi.org/10.1021/acs.analchem.1c02769 |
id |
ftanrparis:oai:HAL:hal-03454238v1 |
---|---|
record_format |
openpolar |
spelling |
ftanrparis:oai:HAL:hal-03454238v1 2024-09-15T18:30:31+00:00 Development of Mercury Analysis by NanoSIMS for the Localization of Mercury–Selenium Particles in Whale Liver Schaumlöffel, Dirk Subirana, Maria Angels Paton, Lhiam Hall, James Brownlow, Andrew Krupp, Eva, M Feldmann, Jörg Angels Subirana, Maria Institut des sciences analytiques et de physico-chimie pour l'environnement et les materiaux (IPREM) Université de Pau et des Pays de l'Adour (UPPA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS) Scottish Marine Animal Stranding Scheme, SRUC Veterinary Service Scotland's Rural College (SRUC) Laboratoire de Chimie Analytique Bio-Inorganique et Environnement (LCABIE) Université de Pau et des Pays de l'Adour (UPPA)-Centre National de la Recherche Scientifique (CNRS) Karl-Franzens-Universität Graz ANR-11-EQPX-0027,MARSS,Centre de Spectrometrie de Masse pour les Sciences de la Réactivité et de Spéciation(2011) 2021-09-21 https://hal.science/hal-03454238 https://hal.science/hal-03454238/document https://hal.science/hal-03454238/file/NanoSIMS_mercury.pdf https://doi.org/10.1021/acs.analchem.1c02769 en eng HAL CCSD American Chemical Society info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.analchem.1c02769 hal-03454238 https://hal.science/hal-03454238 https://hal.science/hal-03454238/document https://hal.science/hal-03454238/file/NanoSIMS_mercury.pdf doi:10.1021/acs.analchem.1c02769 info:eu-repo/semantics/OpenAccess ISSN: 0003-2700 EISSN: 1520-6882 Analytical Chemistry https://hal.science/hal-03454238 Analytical Chemistry, 2021, 93 (37), pp.12733-12739. ⟨10.1021/acs.analchem.1c02769⟩ NanoSIMS mercury selenium rf plasma oxygen ion source whale liver [CHIM.ANAL]Chemical Sciences/Analytical chemistry info:eu-repo/semantics/article Journal articles 2021 ftanrparis https://doi.org/10.1021/acs.analchem.1c02769 2024-07-12T10:56:09Z International audience Nanoscale secondary ion mass spectrometry (NanoSIMS) is a dynamic SIMS technique, which offers high spatial resolution allowing the mapping of chemical elements at the nanometer scale combined with high sensitivity. However, SIMS for mercury analysis is a challenging issue due to the low secondary ion yield and has never been done on NanoSIMS. The introduction of an rf plasma oxygen primary ion source on NanoSIMS enabled higher lateral resolution and higher sensitivity for electropositive elements such as most metals. In this paper, for the first time mercury analysis by NanoSIMS was developed applying the new rf plasma Oion source. All mercury isotopes could be detected as Hg + secondary ions and the isotopic pattern corresponded to their natural isotopic abundances. Furthermore, Hg + detection in HgSe nanocrystals has been investigated where polyatomic interferences from selenium clusters were identified and separated by high mass resolution (/M ≥ 3200). However, in presence of selenium a strong matrix effect was observed decreasing the Hg + secondary ion yield. In addition, a detection of Se + ions was possible, too. The newly developed method was successfully applied to nanoscale localization by chemical imaging of HgSe particles accumulated in liver tissue of sperm whale (Physeter macrocephalus). This demonstrated the applicability of NanoSIMS not only for mercury detection in surface analysis but also for mercury mapping in biological samples. Article in Journal/Newspaper Physeter macrocephalus Sperm whale Portail HAL-ANR (Agence Nationale de la Recherche) Analytical Chemistry 93 37 12733 12739 |
institution |
Open Polar |
collection |
Portail HAL-ANR (Agence Nationale de la Recherche) |
op_collection_id |
ftanrparis |
language |
English |
topic |
NanoSIMS mercury selenium rf plasma oxygen ion source whale liver [CHIM.ANAL]Chemical Sciences/Analytical chemistry |
spellingShingle |
NanoSIMS mercury selenium rf plasma oxygen ion source whale liver [CHIM.ANAL]Chemical Sciences/Analytical chemistry Schaumlöffel, Dirk Subirana, Maria Angels Paton, Lhiam Hall, James Brownlow, Andrew Krupp, Eva, M Feldmann, Jörg Angels Subirana, Maria Development of Mercury Analysis by NanoSIMS for the Localization of Mercury–Selenium Particles in Whale Liver |
topic_facet |
NanoSIMS mercury selenium rf plasma oxygen ion source whale liver [CHIM.ANAL]Chemical Sciences/Analytical chemistry |
description |
International audience Nanoscale secondary ion mass spectrometry (NanoSIMS) is a dynamic SIMS technique, which offers high spatial resolution allowing the mapping of chemical elements at the nanometer scale combined with high sensitivity. However, SIMS for mercury analysis is a challenging issue due to the low secondary ion yield and has never been done on NanoSIMS. The introduction of an rf plasma oxygen primary ion source on NanoSIMS enabled higher lateral resolution and higher sensitivity for electropositive elements such as most metals. In this paper, for the first time mercury analysis by NanoSIMS was developed applying the new rf plasma Oion source. All mercury isotopes could be detected as Hg + secondary ions and the isotopic pattern corresponded to their natural isotopic abundances. Furthermore, Hg + detection in HgSe nanocrystals has been investigated where polyatomic interferences from selenium clusters were identified and separated by high mass resolution (/M ≥ 3200). However, in presence of selenium a strong matrix effect was observed decreasing the Hg + secondary ion yield. In addition, a detection of Se + ions was possible, too. The newly developed method was successfully applied to nanoscale localization by chemical imaging of HgSe particles accumulated in liver tissue of sperm whale (Physeter macrocephalus). This demonstrated the applicability of NanoSIMS not only for mercury detection in surface analysis but also for mercury mapping in biological samples. |
author2 |
Institut des sciences analytiques et de physico-chimie pour l'environnement et les materiaux (IPREM) Université de Pau et des Pays de l'Adour (UPPA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS) Scottish Marine Animal Stranding Scheme, SRUC Veterinary Service Scotland's Rural College (SRUC) Laboratoire de Chimie Analytique Bio-Inorganique et Environnement (LCABIE) Université de Pau et des Pays de l'Adour (UPPA)-Centre National de la Recherche Scientifique (CNRS) Karl-Franzens-Universität Graz ANR-11-EQPX-0027,MARSS,Centre de Spectrometrie de Masse pour les Sciences de la Réactivité et de Spéciation(2011) |
format |
Article in Journal/Newspaper |
author |
Schaumlöffel, Dirk Subirana, Maria Angels Paton, Lhiam Hall, James Brownlow, Andrew Krupp, Eva, M Feldmann, Jörg Angels Subirana, Maria |
author_facet |
Schaumlöffel, Dirk Subirana, Maria Angels Paton, Lhiam Hall, James Brownlow, Andrew Krupp, Eva, M Feldmann, Jörg Angels Subirana, Maria |
author_sort |
Schaumlöffel, Dirk |
title |
Development of Mercury Analysis by NanoSIMS for the Localization of Mercury–Selenium Particles in Whale Liver |
title_short |
Development of Mercury Analysis by NanoSIMS for the Localization of Mercury–Selenium Particles in Whale Liver |
title_full |
Development of Mercury Analysis by NanoSIMS for the Localization of Mercury–Selenium Particles in Whale Liver |
title_fullStr |
Development of Mercury Analysis by NanoSIMS for the Localization of Mercury–Selenium Particles in Whale Liver |
title_full_unstemmed |
Development of Mercury Analysis by NanoSIMS for the Localization of Mercury–Selenium Particles in Whale Liver |
title_sort |
development of mercury analysis by nanosims for the localization of mercury–selenium particles in whale liver |
publisher |
HAL CCSD |
publishDate |
2021 |
url |
https://hal.science/hal-03454238 https://hal.science/hal-03454238/document https://hal.science/hal-03454238/file/NanoSIMS_mercury.pdf https://doi.org/10.1021/acs.analchem.1c02769 |
genre |
Physeter macrocephalus Sperm whale |
genre_facet |
Physeter macrocephalus Sperm whale |
op_source |
ISSN: 0003-2700 EISSN: 1520-6882 Analytical Chemistry https://hal.science/hal-03454238 Analytical Chemistry, 2021, 93 (37), pp.12733-12739. ⟨10.1021/acs.analchem.1c02769⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.analchem.1c02769 hal-03454238 https://hal.science/hal-03454238 https://hal.science/hal-03454238/document https://hal.science/hal-03454238/file/NanoSIMS_mercury.pdf doi:10.1021/acs.analchem.1c02769 |
op_rights |
info:eu-repo/semantics/OpenAccess |
op_doi |
https://doi.org/10.1021/acs.analchem.1c02769 |
container_title |
Analytical Chemistry |
container_volume |
93 |
container_issue |
37 |
container_start_page |
12733 |
op_container_end_page |
12739 |
_version_ |
1810471977891135488 |