A review of the potential effects of climate change on disseminated neoplasia with an emphasis on efficient detection in marine bivalve populations

• Published in: Science of The Total Environment
• Main Authors: Bramwell, Georgina, Schultz, Aaron, Sherman, Craig D.H., Giraudeau, Mathieu, Thomas, Frédéric, Ujvari, Beata, Dujon, Antoine, M
• Other Authors: Deakin University Waurn Ponds, Centre de Recherches Ecologiques et Evolutives sur le Cancer (MIVEGEC-CREEC), Processus Écologiques et Évolutifs au sein des Communautés (PEEC), Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD France-Sud )-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD France-Sud )-Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD France-Sud )-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD France-Sud ), Deakin University Burwood, Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD France-Sud ), LIttoral ENvironnement et Sociétés (LIENSs), La Rochelle Université (ULR)-Centre National de la Recherche Scientifique (CNRS), Deakin University, Burwood, Australia, ANR-18-CE35-0009,TRANSCAN,ECOLOGIE ET EVOLUTION DES CANCERS TRANSMISSIBLES(2018)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2021
• Subjects: Disease Outbreaks; Epizootiology; Emerging disease; Ocean acidification; Global warming; Aquatic ecosystems; Aquaculture; Molluscs; [SDE]Environmental Sciences; [SDV]Life Sciences [q-bio]
• Online Access: https://hal.science/hal-03418468; https://doi.org/10.1016/j.scitotenv.2021.145134

International audience Climate change not only directly impacts marine environments by shifting water temperatures, salinity, pH and dissolved oxygen concentrations, but may also indirectly contribute to the emergence of additional ecosystem stressors, such as infectious diseases, including bivalve disseminated neoplasia. Disseminated neoplasia, a form of cancer found in some bivalves - recently discovered to be transmissible in at least six species - has been shown to impair bivalve health and fitness, with occasional mass outbreaks causing high levels of mortality. As the ability of the host bivalve to respond to disseminated neoplasia, and the survival and transmissibility of disseminated neoplasia both depend on environmental factors, it is crucial to understand the interaction between climate change and disseminated neoplasia epidemiology. Furthermore, with bivalves being species of high ecological and economic importance, there is a rising need for the development of efficient disseminated neoplasia diagnostic tools in order to detect, mitigate and potentially prevent deleterious disseminated neoplasia outbreaks. Therefore, in this study, we reviewed the current knowledge of climate impacted environmental parameters on disseminated neoplasia and identified best practices and methodology for the detection of transmissible disseminated neoplasia in the wild. By exploring the potential effects changing climate has on disseminated neoplasia dynamics, we identified future research directions in order to advance the field. This included using state of the art disease detection methods and taking into account species' ecological niches to understand the dynamic of disseminated neoplasia outbreaks in the wild and to investigate whether disseminated neoplasia is present in freshwater ecosystems. Finally, we provided a comprehensive step-by-step guideline for an evidence-based detection of this disease in marine ecosystems.