Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles
MM wants to thank ANID Centros Basales, ACE210012. MM quiere agradecer a ANID Centros Basales, ACE210012. Artemisia plants are traditional and ethnopharmacologically used to treat several diseases and in addition in food, spices, and beverages. The genus is widely distributed in all continents excep...
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ftanid:oai:repositorio.anid.cl:10533/78889 2024-09-15T17:48:50+00:00 Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles Calina, Daniela Sharifi-Rad, Javad Herrera-Bravo, Jesus Semwal, Prabhakar Painuli, Sakshi Badoni, Himani Ezzat, Shahira M. Farid, Mai M. Merghany, Rana M. Aborehab, Nora M. Salem, Mohamed A. Sen, Surjit Acharya, Krishnendu Lapava, Natallia Martorell, Miquel Tynybekov, Bekzat Calina, Daniela Cho, William C. 2024-08-26T17:18:26Z PDF https://hdl.handle.net/10533/78889 https://doi.org/10.1155/2022/5628601 https://repositorio.ufro.cl/s/repositorio-ufro/item/7257 en eng doi:10.1155/2022/5628601 https://repositorio.ufro.cl/s/repositorio-ufro/item/7257 https://hdl.handle.net/10533/78889 OXIDATIVE MEDICINE AND CELLULAR LONGEVITY ESSENTIAL OIL ANTIOXIDANT ACTIVITY MOLECULAR PHYLOGENY ANTICANCER ACTIVITY ALLIES ANTHEMIDEAE FALCIPARUM-MALARIA ENDEMIC ARTEMISIA GENUS ARTEMISIA ABSINTHIUM-L LEAF EXTRACT artículo de revisión 2024 ftanid https://doi.org/10.1155/2022/5628601 2024-09-01T23:42:49Z MM wants to thank ANID Centros Basales, ACE210012. MM quiere agradecer a ANID Centros Basales, ACE210012. Artemisia plants are traditional and ethnopharmacologically used to treat several diseases and in addition in food, spices, and beverages. The genus is widely distributed in all continents except the Antarctica, and traditional medicine has been used as antimalarial, antioxidant, anticancer, antinociceptive, anti-inflammatory, and antiviral agents. This review is aimed at systematizing scientific data on the geographical distribution, chemical composition, and pharmacological and toxicological profiles of the Artemisia genus. Data from the literature on Artemisia plants were taken using electronic databases such as PubMed/MEDLINE, Scopus, and Web of Science. Selected papers for this updated study included data about phytochemicals, preclinical pharmacological experimental studies with molecular mechanisms included, clinical studies, and toxicological and safety data. In addition, ancient texts and books were consulted. The essential oils and phytochemicals of the Artemisia genus have reported important biological activities, among them the artemisinin, a sesquiterpene lactone, with antimalarial activity. Artemisia absinthium L. is one of the most famous Artemisia spp. due to its use in the production of the absinthe drink which is restricted in most countries because of neurotoxicity. The analyzed studies confirmed that Artemisia plants have many traditional and pharmacological applications. However, scientific data are limited to clinical and toxicological research. Therefore, further research is needed on these aspects to understand the full therapeutic potential and molecular pharmacological mechanisms of this medicinal species. Article in Journal/Newspaper Antarc* Antarctica Repositorio ANID (Agencia Nacional de Investigación y Desarrollo) Oxidative Medicine and Cellular Longevity 2022 1 23 |
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Repositorio ANID (Agencia Nacional de Investigación y Desarrollo) |
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language |
English |
topic |
ESSENTIAL OIL ANTIOXIDANT ACTIVITY MOLECULAR PHYLOGENY ANTICANCER ACTIVITY ALLIES ANTHEMIDEAE FALCIPARUM-MALARIA ENDEMIC ARTEMISIA GENUS ARTEMISIA ABSINTHIUM-L LEAF EXTRACT |
spellingShingle |
ESSENTIAL OIL ANTIOXIDANT ACTIVITY MOLECULAR PHYLOGENY ANTICANCER ACTIVITY ALLIES ANTHEMIDEAE FALCIPARUM-MALARIA ENDEMIC ARTEMISIA GENUS ARTEMISIA ABSINTHIUM-L LEAF EXTRACT Calina, Daniela Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
topic_facet |
ESSENTIAL OIL ANTIOXIDANT ACTIVITY MOLECULAR PHYLOGENY ANTICANCER ACTIVITY ALLIES ANTHEMIDEAE FALCIPARUM-MALARIA ENDEMIC ARTEMISIA GENUS ARTEMISIA ABSINTHIUM-L LEAF EXTRACT |
description |
MM wants to thank ANID Centros Basales, ACE210012. MM quiere agradecer a ANID Centros Basales, ACE210012. Artemisia plants are traditional and ethnopharmacologically used to treat several diseases and in addition in food, spices, and beverages. The genus is widely distributed in all continents except the Antarctica, and traditional medicine has been used as antimalarial, antioxidant, anticancer, antinociceptive, anti-inflammatory, and antiviral agents. This review is aimed at systematizing scientific data on the geographical distribution, chemical composition, and pharmacological and toxicological profiles of the Artemisia genus. Data from the literature on Artemisia plants were taken using electronic databases such as PubMed/MEDLINE, Scopus, and Web of Science. Selected papers for this updated study included data about phytochemicals, preclinical pharmacological experimental studies with molecular mechanisms included, clinical studies, and toxicological and safety data. In addition, ancient texts and books were consulted. The essential oils and phytochemicals of the Artemisia genus have reported important biological activities, among them the artemisinin, a sesquiterpene lactone, with antimalarial activity. Artemisia absinthium L. is one of the most famous Artemisia spp. due to its use in the production of the absinthe drink which is restricted in most countries because of neurotoxicity. The analyzed studies confirmed that Artemisia plants have many traditional and pharmacological applications. However, scientific data are limited to clinical and toxicological research. Therefore, further research is needed on these aspects to understand the full therapeutic potential and molecular pharmacological mechanisms of this medicinal species. |
author2 |
Sharifi-Rad, Javad Herrera-Bravo, Jesus Semwal, Prabhakar Painuli, Sakshi Badoni, Himani Ezzat, Shahira M. Farid, Mai M. Merghany, Rana M. Aborehab, Nora M. Salem, Mohamed A. Sen, Surjit Acharya, Krishnendu Lapava, Natallia Martorell, Miquel Tynybekov, Bekzat Calina, Daniela Cho, William C. |
format |
Article in Journal/Newspaper |
author |
Calina, Daniela |
author_facet |
Calina, Daniela |
author_sort |
Calina, Daniela |
title |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
title_short |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
title_full |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
title_fullStr |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
title_full_unstemmed |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles |
title_sort |
artemisia spp.: an update on its chemical composition, pharmacological and toxicological profiles |
publishDate |
2024 |
url |
https://hdl.handle.net/10533/78889 https://doi.org/10.1155/2022/5628601 https://repositorio.ufro.cl/s/repositorio-ufro/item/7257 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY |
op_relation |
doi:10.1155/2022/5628601 https://repositorio.ufro.cl/s/repositorio-ufro/item/7257 https://hdl.handle.net/10533/78889 |
op_doi |
https://doi.org/10.1155/2022/5628601 |
container_title |
Oxidative Medicine and Cellular Longevity |
container_volume |
2022 |
container_start_page |
1 |
op_container_end_page |
23 |
_version_ |
1810290361462947840 |