Role of alpha-ketoglutarate and (pro)renin receptor in intra-renal angiotensin II formation, Na+ reabsorption and blood pressure in diabetic disease.

• Main Authors: Gonzalez - Parra, Alexis
• Other Authors: Pontificia Universidad Catolica De Valparaiso
• Format: Report
• Language: unknown
• Published: 2023
• Subjects: Diabetes Renin angiotensin system Hypertension; Fisiologia; Magallanes; Valparaíso; Bío Bío; General Bernardo O'Higgins; Antártica
• Online Access: https://hdl.handle.net/10533/49044

PROJECT RESULTS: In the original proposal we planned to answer the following questions: • Does streptozotocin (STZ)-induced type I diabetic mice having high plasma and urinary glucose have increased PRR expression via aKG-activation of OXGR1? Does OXGR1 antagonism prevent tubular Ang II formation, N...