Chemical-biological study (in vitro and in vivo) of new analogues of triazolopyridines as anti-Trypanosome cruzi, the effect on sterol pathways.

• Main Authors: Lapier - Quezada, Michel
• Other Authors: Universidad De Chile
• Format: Report
• Language: unknown
• Published: 2023
• Subjects: triazolopyridines sterol pathways Trypanosome cruzi; Ciencias Quimicas; Baja; Blanco; Magallanes; Valparaíso; Bío Bío; General Bernardo O'Higgins; Antártica
• Online Access: https://hdl.handle.net/10533/48416

3 Evaluate candidates for antichagasic drugs in vivo, identifying the trypanocidal and cytotoxic effects in an acute murine model of the infection. PARCIAL En fase preliminar se determinó la solubilidad y la biodisponibilidad de las moléculas candidatas. Sin embargo no se realizaron los experimentos...