Potential allergens of the Pacific Oyster (Crassostrea gigas)
This dataset consists of a spreadsheet in MS Excel (.xlsx) and Open Document formats (.ods) The increasing production and consumption of molluscs are associated with a rise in the prevalence of mollusc allergy worldwide, currently affecting 0.2% to 1.3% of the general population. However, the elucid...
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James Cook University
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ftands:oai:ands.org.au::815651 2024-09-15T18:03:06+00:00 Potential allergens of the Pacific Oyster (Crassostrea gigas) Kyall Zenger (hasAssociationWith) Ludwig Ludwig Lopata (hasAssociationWith) Ludwig Ludwig Lopata (hasCollector) Roni Benjamin Krieser (hasAssociationWith) Roni Benjamin Krieser (hasCollector) Sandip Kamath (hasCollector) Sandip Kamath (hasAssociationWith) Spatial: https://researchdata.edu.au/potential-allergens-pacific-crassostrea-gigas/815651 https://researchdata.jcu.edu.au//published/99a172a23c48f66d51a50bd0f7720c58 https://doi.org/10.4225/28/588ebc2ca00e2 unknown James Cook University https://researchdata.edu.au/potential-allergens-pacific-crassostrea-gigas/815651 06dd1f377cbc62ea860a60c09651c572 https://researchdata.jcu.edu.au//published/99a172a23c48f66d51a50bd0f7720c58 doi:10.4225/28/588ebc2ca00e2 https://researchdata.jcu.edu.au// food allergens oyster genomic in-silico immunoinformatics dataset ftands https://doi.org/10.4225/28/588ebc2ca00e2 2024-08-27T00:01:57Z This dataset consists of a spreadsheet in MS Excel (.xlsx) and Open Document formats (.ods) The increasing production and consumption of molluscs are associated with a rise in the prevalence of mollusc allergy worldwide, currently affecting 0.2% to 1.3% of the general population. However, the elucidation of mollusc allergens, crucial for better diagnostics, still lags behind other seafood groups such as fish and crustacean. Genomic data have previously been utilized for the improved identification of non-food allergens by performing similarity searches using the BLAST program. Based on the published genome of the Pacific oyster (Crassostrea gigas) we aimed to identify the repertoire of potential allergen using bioinformatics analysis and sought to validate allergenicity using a combination of immuno-chemical methods and proteomic analysis. A repertoire of 25,982 genome-derived proteomes of the Pacific oyster were aligned with 2117 allergen sequences resulting in over 800 protein homologues. Of those, 95 proteins were potentially cross-reactive allergens due to high identity with known allergens (>50% identity). Analysis of the transcriptomic data showed the proteins were differentially expressed across tissue of the oyster. Dataset Crassostrea gigas Pacific oyster Research Data Australia (Australian National Data Service - ANDS) |
institution |
Open Polar |
collection |
Research Data Australia (Australian National Data Service - ANDS) |
op_collection_id |
ftands |
language |
unknown |
topic |
food allergens oyster genomic in-silico immunoinformatics |
spellingShingle |
food allergens oyster genomic in-silico immunoinformatics Potential allergens of the Pacific Oyster (Crassostrea gigas) |
topic_facet |
food allergens oyster genomic in-silico immunoinformatics |
description |
This dataset consists of a spreadsheet in MS Excel (.xlsx) and Open Document formats (.ods) The increasing production and consumption of molluscs are associated with a rise in the prevalence of mollusc allergy worldwide, currently affecting 0.2% to 1.3% of the general population. However, the elucidation of mollusc allergens, crucial for better diagnostics, still lags behind other seafood groups such as fish and crustacean. Genomic data have previously been utilized for the improved identification of non-food allergens by performing similarity searches using the BLAST program. Based on the published genome of the Pacific oyster (Crassostrea gigas) we aimed to identify the repertoire of potential allergen using bioinformatics analysis and sought to validate allergenicity using a combination of immuno-chemical methods and proteomic analysis. A repertoire of 25,982 genome-derived proteomes of the Pacific oyster were aligned with 2117 allergen sequences resulting in over 800 protein homologues. Of those, 95 proteins were potentially cross-reactive allergens due to high identity with known allergens (>50% identity). Analysis of the transcriptomic data showed the proteins were differentially expressed across tissue of the oyster. |
author2 |
Kyall Zenger (hasAssociationWith) Ludwig Ludwig Lopata (hasAssociationWith) Ludwig Ludwig Lopata (hasCollector) Roni Benjamin Krieser (hasAssociationWith) Roni Benjamin Krieser (hasCollector) Sandip Kamath (hasCollector) Sandip Kamath (hasAssociationWith) |
format |
Dataset |
title |
Potential allergens of the Pacific Oyster (Crassostrea gigas) |
title_short |
Potential allergens of the Pacific Oyster (Crassostrea gigas) |
title_full |
Potential allergens of the Pacific Oyster (Crassostrea gigas) |
title_fullStr |
Potential allergens of the Pacific Oyster (Crassostrea gigas) |
title_full_unstemmed |
Potential allergens of the Pacific Oyster (Crassostrea gigas) |
title_sort |
potential allergens of the pacific oyster (crassostrea gigas) |
publisher |
James Cook University |
url |
https://researchdata.edu.au/potential-allergens-pacific-crassostrea-gigas/815651 https://researchdata.jcu.edu.au//published/99a172a23c48f66d51a50bd0f7720c58 https://doi.org/10.4225/28/588ebc2ca00e2 |
op_coverage |
Spatial: |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_source |
https://researchdata.jcu.edu.au// |
op_relation |
https://researchdata.edu.au/potential-allergens-pacific-crassostrea-gigas/815651 06dd1f377cbc62ea860a60c09651c572 https://researchdata.jcu.edu.au//published/99a172a23c48f66d51a50bd0f7720c58 doi:10.4225/28/588ebc2ca00e2 |
op_doi |
https://doi.org/10.4225/28/588ebc2ca00e2 |
_version_ |
1810440628730855424 |