Diagnosing dementia in the Arctic:translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit
Background: The ageing Arctic populations raise the need for work-up of cognitive function that reflects language and cultural understandings.Aim: To translate and evaluate tools for work-up of cognitive impairment in Greenland.Methods: Step A: An expert panel was established to select tools suitabl...
Published in: | International Journal of Circumpolar Health |
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2021
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Online Access: | https://vbn.aau.dk/da/publications/95d0f3d8-ccdf-4c60-af39-f7dedf8e1674 https://doi.org/10.1080/22423982.2021.1948247 https://vbn.aau.dk/ws/files/427267409/Kleist_et_al._2021_Diagnosing_dementia_in_the_Arctic.pdf |
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ftalborgunivpubl:oai:pure.atira.dk:publications/95d0f3d8-ccdf-4c60-af39-f7dedf8e1674 2024-06-23T07:48:36+00:00 Diagnosing dementia in the Arctic:translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit Kleist, Inaluk Noahsen, Paneeraq Gredal, Ole Riis, Johannes Andersen, Stig 2021-12 application/pdf https://vbn.aau.dk/da/publications/95d0f3d8-ccdf-4c60-af39-f7dedf8e1674 https://doi.org/10.1080/22423982.2021.1948247 https://vbn.aau.dk/ws/files/427267409/Kleist_et_al._2021_Diagnosing_dementia_in_the_Arctic.pdf eng eng https://vbn.aau.dk/da/publications/95d0f3d8-ccdf-4c60-af39-f7dedf8e1674 info:eu-repo/semantics/openAccess Kleist , I , Noahsen , P , Gredal , O , Riis , J & Andersen , S 2021 , ' Diagnosing dementia in the Arctic : translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit ' , International Journal of Circumpolar Health , vol. 80 , no. 1 , 1948247 . https://doi.org/10.1080/22423982.2021.1948247 article 2021 ftalborgunivpubl https://doi.org/10.1080/22423982.2021.1948247 2024-06-03T15:09:35Z Background: The ageing Arctic populations raise the need for work-up of cognitive function that reflects language and cultural understandings.Aim: To translate and evaluate tools for work-up of cognitive impairment in Greenland.Methods: Step A: An expert panel was established to select tools suitable for the work-up of cognitive impairment at three different settings in Greenland. Step B: Tools were translated in a multiple-step process of independent translations with back-translation and adaptations by two independent translators and two Greenlandic physicians. Step C: a testing and validation process of the tools at three locations: the national hospital in the capital city; regional hospital in a town; health care centre in a small town.Results: Tools selected were Mini-Cog and RUDAS. Participants for testing of tools were 43 of 61 invited, of which six had dementia. RUDAS and Mini-Cog scores were associated (p < 0.001). The smoothed AUC was 0.87 (95%-CI, 0.65-0.95) for Mini-Cog and 0.90 (95%-CI, 0.76-0.97) for RUDAS. The sensitivity of Mini-Cog with a cut-off at ≤3 was 83.3%, and specificity was 62.2%. For RUDAS with a cut-off at ≤23, these were 100% and 75.7%, respectively.Conclusion: Requested tools have been translated for assessing cognitive function in the native Arctic setting. Small town residents with a Mini-Cog score of 3 or lower should be referred to a regional hospital for RUDAS, and a score of 23 or less should cause referral to the national hospital for a full work-up of cognitive function. Article in Journal/Newspaper Arctic Arctic Circumpolar Health Greenland greenlandic International Journal of Circumpolar Health inuit Aalborg University's Research Portal Arctic Greenland International Journal of Circumpolar Health 80 1 1948247 |
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Open Polar |
collection |
Aalborg University's Research Portal |
op_collection_id |
ftalborgunivpubl |
language |
English |
description |
Background: The ageing Arctic populations raise the need for work-up of cognitive function that reflects language and cultural understandings.Aim: To translate and evaluate tools for work-up of cognitive impairment in Greenland.Methods: Step A: An expert panel was established to select tools suitable for the work-up of cognitive impairment at three different settings in Greenland. Step B: Tools were translated in a multiple-step process of independent translations with back-translation and adaptations by two independent translators and two Greenlandic physicians. Step C: a testing and validation process of the tools at three locations: the national hospital in the capital city; regional hospital in a town; health care centre in a small town.Results: Tools selected were Mini-Cog and RUDAS. Participants for testing of tools were 43 of 61 invited, of which six had dementia. RUDAS and Mini-Cog scores were associated (p < 0.001). The smoothed AUC was 0.87 (95%-CI, 0.65-0.95) for Mini-Cog and 0.90 (95%-CI, 0.76-0.97) for RUDAS. The sensitivity of Mini-Cog with a cut-off at ≤3 was 83.3%, and specificity was 62.2%. For RUDAS with a cut-off at ≤23, these were 100% and 75.7%, respectively.Conclusion: Requested tools have been translated for assessing cognitive function in the native Arctic setting. Small town residents with a Mini-Cog score of 3 or lower should be referred to a regional hospital for RUDAS, and a score of 23 or less should cause referral to the national hospital for a full work-up of cognitive function. |
format |
Article in Journal/Newspaper |
author |
Kleist, Inaluk Noahsen, Paneeraq Gredal, Ole Riis, Johannes Andersen, Stig |
spellingShingle |
Kleist, Inaluk Noahsen, Paneeraq Gredal, Ole Riis, Johannes Andersen, Stig Diagnosing dementia in the Arctic:translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
author_facet |
Kleist, Inaluk Noahsen, Paneeraq Gredal, Ole Riis, Johannes Andersen, Stig |
author_sort |
Kleist, Inaluk |
title |
Diagnosing dementia in the Arctic:translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
title_short |
Diagnosing dementia in the Arctic:translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
title_full |
Diagnosing dementia in the Arctic:translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
title_fullStr |
Diagnosing dementia in the Arctic:translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
title_full_unstemmed |
Diagnosing dementia in the Arctic:translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
title_sort |
diagnosing dementia in the arctic:translating tools and developing and validating an algorithm for assessment of impaired cognitive function in greenland inuit |
publishDate |
2021 |
url |
https://vbn.aau.dk/da/publications/95d0f3d8-ccdf-4c60-af39-f7dedf8e1674 https://doi.org/10.1080/22423982.2021.1948247 https://vbn.aau.dk/ws/files/427267409/Kleist_et_al._2021_Diagnosing_dementia_in_the_Arctic.pdf |
geographic |
Arctic Greenland |
geographic_facet |
Arctic Greenland |
genre |
Arctic Arctic Circumpolar Health Greenland greenlandic International Journal of Circumpolar Health inuit |
genre_facet |
Arctic Arctic Circumpolar Health Greenland greenlandic International Journal of Circumpolar Health inuit |
op_source |
Kleist , I , Noahsen , P , Gredal , O , Riis , J & Andersen , S 2021 , ' Diagnosing dementia in the Arctic : translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit ' , International Journal of Circumpolar Health , vol. 80 , no. 1 , 1948247 . https://doi.org/10.1080/22423982.2021.1948247 |
op_relation |
https://vbn.aau.dk/da/publications/95d0f3d8-ccdf-4c60-af39-f7dedf8e1674 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1080/22423982.2021.1948247 |
container_title |
International Journal of Circumpolar Health |
container_volume |
80 |
container_issue |
1 |
container_start_page |
1948247 |
_version_ |
1802638957218889728 |