A nationwide registry-based observational study of thyroid disease incidence in the Faroe Islands
OBJECTIVE: The occurrence of thyroid disease varies among populations. While the iodine nutrition level of the Faroese seems to have been decreasing over the past decades, there is no systematic evaluation of the thyroid disease pattern in the Faroe Islands. Such knowledge of thyroid disease occurre...
Published in: | Clinical Endocrinology |
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2024
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Online Access: | https://vbn.aau.dk/da/publications/192ca87f-cfe5-4ed1-8950-1f3e579a34a4 https://doi.org/10.1111/cen.15050 https://vbn.aau.dk/ws/files/714705125/Johannesen_et_al._2024_._A_nationwide_registry-based_observational_study_of_thyroid_disease_incidence_in_the_Faroe_Islands.pdf http://www.scopus.com/inward/record.url?scp=85188062507&partnerID=8YFLogxK |
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ftalborgunivpubl:oai:pure.atira.dk:publications/192ca87f-cfe5-4ed1-8950-1f3e579a34a4 2024-09-15T18:05:34+00:00 A nationwide registry-based observational study of thyroid disease incidence in the Faroe Islands Johannesen, Herborg Líggjasardóttir Veyhe, Anna Sofía Andreassen, Jens Weihe, Pál Strøm, Marin Andorsdóttir, Guðrið Rasmussen, Aase Krogh Feldt-Rasmussen, Ulla Carlé, Allan Andersen, Stig 2024-06 application/pdf https://vbn.aau.dk/da/publications/192ca87f-cfe5-4ed1-8950-1f3e579a34a4 https://doi.org/10.1111/cen.15050 https://vbn.aau.dk/ws/files/714705125/Johannesen_et_al._2024_._A_nationwide_registry-based_observational_study_of_thyroid_disease_incidence_in_the_Faroe_Islands.pdf http://www.scopus.com/inward/record.url?scp=85188062507&partnerID=8YFLogxK eng eng https://vbn.aau.dk/da/publications/192ca87f-cfe5-4ed1-8950-1f3e579a34a4 info:eu-repo/semantics/openAccess Johannesen , H L , Veyhe , A S , Andreassen , J , Weihe , P , Strøm , M , Andorsdóttir , G , Rasmussen , A K , Feldt-Rasmussen , U , Carlé , A & Andersen , S 2024 , ' A nationwide registry-based observational study of thyroid disease incidence in the Faroe Islands ' , Clinical Endocrinology , vol. 100 , no. 6 , pp. 575-584 . https://doi.org/10.1111/cen.15050 Subarctic society The Faroe Islands The North Atlantic Ocean incidence thyroid disease article 2024 ftalborgunivpubl https://doi.org/10.1111/cen.15050 2024-09-05T14:36:16Z OBJECTIVE: The occurrence of thyroid disease varies among populations. While the iodine nutrition level of the Faroese seems to have been decreasing over the past decades, there is no systematic evaluation of the thyroid disease pattern in the Faroe Islands. Such knowledge of thyroid disease occurrence in the North Atlantic region may support healthcare planning and prevention. To investigate incidence rates, including subtypes of thyroid diseases, and demographic characteristics of thyroid disease patients in the Faroe Islands, to improve understanding of the patterns and trends of these disorders. DESIGN AND METHOD: A registry-based observational study was conducted over 10 years, encompassing all adult Faroese individuals. PATIENTS AND MEASUREMENTS: Health records from general practitioners and hospitals were used to identify incident cases of thyroid diseases. Validation was performed using multiple data sources. The incidence rates were standardised using population data from the middle of the study period 2006-2018. RESULTS: Among the 1152 individuals diagnosed with thyroid disease, the standardised incidence rates per 100,000 person-years were 55 for hyperthyroidism and 112 for hypothyroidism, and around four times higher in women than in men. Hashimoto's thyroiditis was the dominant cause of hypothyroidism, while Graves' disease was the leading cause of hyperthyroidism. The incidence of hypothyroidism increases with age. A decreasing trend was observed over time for both hypothyroidism and hyperthyroidism. CONCLUSION: Considering the decrease in iodine nutrition levels over the past decades, we were surprised by the high incidence of autoimmune thyroid disease. The findings highlight the need for continuous monitoring of thyroid disease occurrence in coastal areas of the North Atlantic Ocean. Article in Journal/Newspaper Faroe Islands North Atlantic Subarctic Aalborg University's Research Portal Clinical Endocrinology 100 6 575 584 |
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Open Polar |
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Aalborg University's Research Portal |
op_collection_id |
ftalborgunivpubl |
language |
English |
topic |
Subarctic society The Faroe Islands The North Atlantic Ocean incidence thyroid disease |
spellingShingle |
Subarctic society The Faroe Islands The North Atlantic Ocean incidence thyroid disease Johannesen, Herborg Líggjasardóttir Veyhe, Anna Sofía Andreassen, Jens Weihe, Pál Strøm, Marin Andorsdóttir, Guðrið Rasmussen, Aase Krogh Feldt-Rasmussen, Ulla Carlé, Allan Andersen, Stig A nationwide registry-based observational study of thyroid disease incidence in the Faroe Islands |
topic_facet |
Subarctic society The Faroe Islands The North Atlantic Ocean incidence thyroid disease |
description |
OBJECTIVE: The occurrence of thyroid disease varies among populations. While the iodine nutrition level of the Faroese seems to have been decreasing over the past decades, there is no systematic evaluation of the thyroid disease pattern in the Faroe Islands. Such knowledge of thyroid disease occurrence in the North Atlantic region may support healthcare planning and prevention. To investigate incidence rates, including subtypes of thyroid diseases, and demographic characteristics of thyroid disease patients in the Faroe Islands, to improve understanding of the patterns and trends of these disorders. DESIGN AND METHOD: A registry-based observational study was conducted over 10 years, encompassing all adult Faroese individuals. PATIENTS AND MEASUREMENTS: Health records from general practitioners and hospitals were used to identify incident cases of thyroid diseases. Validation was performed using multiple data sources. The incidence rates were standardised using population data from the middle of the study period 2006-2018. RESULTS: Among the 1152 individuals diagnosed with thyroid disease, the standardised incidence rates per 100,000 person-years were 55 for hyperthyroidism and 112 for hypothyroidism, and around four times higher in women than in men. Hashimoto's thyroiditis was the dominant cause of hypothyroidism, while Graves' disease was the leading cause of hyperthyroidism. The incidence of hypothyroidism increases with age. A decreasing trend was observed over time for both hypothyroidism and hyperthyroidism. CONCLUSION: Considering the decrease in iodine nutrition levels over the past decades, we were surprised by the high incidence of autoimmune thyroid disease. The findings highlight the need for continuous monitoring of thyroid disease occurrence in coastal areas of the North Atlantic Ocean. |
format |
Article in Journal/Newspaper |
author |
Johannesen, Herborg Líggjasardóttir Veyhe, Anna Sofía Andreassen, Jens Weihe, Pál Strøm, Marin Andorsdóttir, Guðrið Rasmussen, Aase Krogh Feldt-Rasmussen, Ulla Carlé, Allan Andersen, Stig |
author_facet |
Johannesen, Herborg Líggjasardóttir Veyhe, Anna Sofía Andreassen, Jens Weihe, Pál Strøm, Marin Andorsdóttir, Guðrið Rasmussen, Aase Krogh Feldt-Rasmussen, Ulla Carlé, Allan Andersen, Stig |
author_sort |
Johannesen, Herborg Líggjasardóttir |
title |
A nationwide registry-based observational study of thyroid disease incidence in the Faroe Islands |
title_short |
A nationwide registry-based observational study of thyroid disease incidence in the Faroe Islands |
title_full |
A nationwide registry-based observational study of thyroid disease incidence in the Faroe Islands |
title_fullStr |
A nationwide registry-based observational study of thyroid disease incidence in the Faroe Islands |
title_full_unstemmed |
A nationwide registry-based observational study of thyroid disease incidence in the Faroe Islands |
title_sort |
nationwide registry-based observational study of thyroid disease incidence in the faroe islands |
publishDate |
2024 |
url |
https://vbn.aau.dk/da/publications/192ca87f-cfe5-4ed1-8950-1f3e579a34a4 https://doi.org/10.1111/cen.15050 https://vbn.aau.dk/ws/files/714705125/Johannesen_et_al._2024_._A_nationwide_registry-based_observational_study_of_thyroid_disease_incidence_in_the_Faroe_Islands.pdf http://www.scopus.com/inward/record.url?scp=85188062507&partnerID=8YFLogxK |
genre |
Faroe Islands North Atlantic Subarctic |
genre_facet |
Faroe Islands North Atlantic Subarctic |
op_source |
Johannesen , H L , Veyhe , A S , Andreassen , J , Weihe , P , Strøm , M , Andorsdóttir , G , Rasmussen , A K , Feldt-Rasmussen , U , Carlé , A & Andersen , S 2024 , ' A nationwide registry-based observational study of thyroid disease incidence in the Faroe Islands ' , Clinical Endocrinology , vol. 100 , no. 6 , pp. 575-584 . https://doi.org/10.1111/cen.15050 |
op_relation |
https://vbn.aau.dk/da/publications/192ca87f-cfe5-4ed1-8950-1f3e579a34a4 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1111/cen.15050 |
container_title |
Clinical Endocrinology |
container_volume |
100 |
container_issue |
6 |
container_start_page |
575 |
op_container_end_page |
584 |
_version_ |
1810443106777038848 |