Pregnancy related changes in some cardiovascular risk factors
Background. Certain risk factors for development of ischemic heart disease are influenced by pregnancy related changes of female sex hormone levels. Postpartum values were similar to prepregnancy levels, except serum triglycerides which remained 35% higher (p<0.001) and blood glucose (p<0.05)....
Published in: | Acta Obstetricia et Gynecologica Scandinavica |
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crwiley:10.3109/00016349609033350 2024-06-09T07:45:56+00:00 Pregnancy related changes in some cardiovascular risk factors Berge, Lillian Nordbø Arnesen, Egil Forsdahl, Anders 1996 http://dx.doi.org/10.3109/00016349609033350 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.3109%2F00016349609033350 https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.3109/00016349609033350 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Acta Obstetricia et Gynecologica Scandinavica volume 75, issue 5, page 439-442 ISSN 0001-6349 1600-0412 journal-article 1996 crwiley https://doi.org/10.3109/00016349609033350 2024-05-16T14:24:38Z Background. Certain risk factors for development of ischemic heart disease are influenced by pregnancy related changes of female sex hormone levels. Postpartum values were similar to prepregnancy levels, except serum triglycerides which remained 35% higher (p<0.001) and blood glucose (p<0.05). Conclusions. The major serum lipid fractions, and blood glucose, were significantly different during pregnancy and postpartum, which may influence the risk of cardiovascular disease development in women. Methods. As a part of the cardiovascular risk factor studies in Finnmark county, Norway, 1974‐75 and 1977‐78, cross‐sectional clinical and non‐fasting laboratory data were obtained prior to conception (n=463), during pregnancy (n=335), and following delivery (n=451). Results. Compared with prepregnancy values, total cholesterol was on average 7% lower in the first trimester (p<0.001), and 30% higher at the end of gestation (p<0.001). High density lipoprotein cholesterol was 38% higher at mid‐pregnancy (jxO.001), but only 14% higher in the last trimester (p<0.01). Serum triglycerides were 18% lower in the first (p<0.001) and 123% higher in the third trimester (p<0.001). Blood glucose was 5% lower than baseline in mid‐pregnancy (p<0.001). Except for the second trimester, when only 27% of women smoked, more than 40% of the women examined were smokers. Article in Journal/Newspaper Finnmark Finnmark Wiley Online Library Norway Acta Obstetricia et Gynecologica Scandinavica 75 5 439 442 |
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English |
description |
Background. Certain risk factors for development of ischemic heart disease are influenced by pregnancy related changes of female sex hormone levels. Postpartum values were similar to prepregnancy levels, except serum triglycerides which remained 35% higher (p<0.001) and blood glucose (p<0.05). Conclusions. The major serum lipid fractions, and blood glucose, were significantly different during pregnancy and postpartum, which may influence the risk of cardiovascular disease development in women. Methods. As a part of the cardiovascular risk factor studies in Finnmark county, Norway, 1974‐75 and 1977‐78, cross‐sectional clinical and non‐fasting laboratory data were obtained prior to conception (n=463), during pregnancy (n=335), and following delivery (n=451). Results. Compared with prepregnancy values, total cholesterol was on average 7% lower in the first trimester (p<0.001), and 30% higher at the end of gestation (p<0.001). High density lipoprotein cholesterol was 38% higher at mid‐pregnancy (jxO.001), but only 14% higher in the last trimester (p<0.01). Serum triglycerides were 18% lower in the first (p<0.001) and 123% higher in the third trimester (p<0.001). Blood glucose was 5% lower than baseline in mid‐pregnancy (p<0.001). Except for the second trimester, when only 27% of women smoked, more than 40% of the women examined were smokers. |
format |
Article in Journal/Newspaper |
author |
Berge, Lillian Nordbø Arnesen, Egil Forsdahl, Anders |
spellingShingle |
Berge, Lillian Nordbø Arnesen, Egil Forsdahl, Anders Pregnancy related changes in some cardiovascular risk factors |
author_facet |
Berge, Lillian Nordbø Arnesen, Egil Forsdahl, Anders |
author_sort |
Berge, Lillian Nordbø |
title |
Pregnancy related changes in some cardiovascular risk factors |
title_short |
Pregnancy related changes in some cardiovascular risk factors |
title_full |
Pregnancy related changes in some cardiovascular risk factors |
title_fullStr |
Pregnancy related changes in some cardiovascular risk factors |
title_full_unstemmed |
Pregnancy related changes in some cardiovascular risk factors |
title_sort |
pregnancy related changes in some cardiovascular risk factors |
publisher |
Wiley |
publishDate |
1996 |
url |
http://dx.doi.org/10.3109/00016349609033350 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.3109%2F00016349609033350 https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.3109/00016349609033350 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Finnmark Finnmark |
genre_facet |
Finnmark Finnmark |
op_source |
Acta Obstetricia et Gynecologica Scandinavica volume 75, issue 5, page 439-442 ISSN 0001-6349 1600-0412 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.3109/00016349609033350 |
container_title |
Acta Obstetricia et Gynecologica Scandinavica |
container_volume |
75 |
container_issue |
5 |
container_start_page |
439 |
op_container_end_page |
442 |
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1801375593552412672 |