International Variations in Hip Fracture Probabilities: Implications for Risk Assessment
Abstract It is recommended that intervention thresholds should be based on absolute fracture risk, but there is a large variation in hip fracture incidence from different regions of the world. The aim of this study was to examine heterogeneity of hip fracture probability in different regions from re...
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crwiley:10.1359/jbmr.2002.17.7.1237 2023-12-03T10:24:59+01:00 International Variations in Hip Fracture Probabilities: Implications for Risk Assessment Kanis, John A. Johnell, Olof De Laet, Chris Jonsson, Bengt Oden, Anders Ogelsby, Alan K. 2002 http://dx.doi.org/10.1359/jbmr.2002.17.7.1237 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1359%2Fjbmr.2002.17.7.1237 https://onlinelibrary.wiley.com/doi/pdf/10.1359/jbmr.2002.17.7.1237 https://onlinelibrary.wiley.com/doi/full-xml/10.1359/jbmr.2002.17.7.1237 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Journal of Bone and Mineral Research volume 17, issue 7, page 1237-1244 ISSN 0884-0431 1523-4681 Orthopedics and Sports Medicine Endocrinology, Diabetes and Metabolism journal-article 2002 crwiley https://doi.org/10.1359/jbmr.2002.17.7.1237 2023-11-09T14:19:59Z Abstract It is recommended that intervention thresholds should be based on absolute fracture risk, but there is a large variation in hip fracture incidence from different regions of the world. The aim of this study was to examine heterogeneity of hip fracture probability in different regions from recent estimates of hip fracture incidence and mortality to adjust intervention thresholds. Ten‐year probabilities of hip fracture were computed in men and women at 10‐year intervals from the age of 50 years and lifetime risks at the age of 50 years from the hazard functions of hip fracture and death. Lifetime risk at the age of 50 years varied from 1% in women from Turkey to 28.5% in women from Sweden. High lifetime risks in women were associated with high lifetime risks in men ( r = 0.83). There also were significant correlations of 10‐year risk at any age between men and women. Ten‐year probability was standardized to that of men and women from Sweden (set at 1.0). There was a 15‐fold range in 10‐year probability from 1.24 in Norway to 0.08 in Chile. Countries were categorized by 10‐year probabilities comprising very high risk (Norway, Iceland, Sweden, Denmark, and the United States), high risk (China [Taiwan {TW}], Germany, Switzerland, Finland, Greece, Canada, The Netherlands, Hungary, Singapore, Italy, United Kingdom, Kuwait, Australia, and Portugal), medium risk (China [Hong Kong {HK}], France, Japan, Spain, Argentina, and China), and low risk (Turkey, Korea, Venezuela, and Chile). The categorization of hip fracture probabilities can be used to adjust intervention thresholds based on age, sex, and relative risk from a reference population such as Sweden. Article in Journal/Newspaper Iceland Wiley Online Library (via Crossref) Canada Norway Argentina Journal of Bone and Mineral Research 17 7 1237 1244 |
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Open Polar |
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Wiley Online Library (via Crossref) |
op_collection_id |
crwiley |
language |
English |
topic |
Orthopedics and Sports Medicine Endocrinology, Diabetes and Metabolism |
spellingShingle |
Orthopedics and Sports Medicine Endocrinology, Diabetes and Metabolism Kanis, John A. Johnell, Olof De Laet, Chris Jonsson, Bengt Oden, Anders Ogelsby, Alan K. International Variations in Hip Fracture Probabilities: Implications for Risk Assessment |
topic_facet |
Orthopedics and Sports Medicine Endocrinology, Diabetes and Metabolism |
description |
Abstract It is recommended that intervention thresholds should be based on absolute fracture risk, but there is a large variation in hip fracture incidence from different regions of the world. The aim of this study was to examine heterogeneity of hip fracture probability in different regions from recent estimates of hip fracture incidence and mortality to adjust intervention thresholds. Ten‐year probabilities of hip fracture were computed in men and women at 10‐year intervals from the age of 50 years and lifetime risks at the age of 50 years from the hazard functions of hip fracture and death. Lifetime risk at the age of 50 years varied from 1% in women from Turkey to 28.5% in women from Sweden. High lifetime risks in women were associated with high lifetime risks in men ( r = 0.83). There also were significant correlations of 10‐year risk at any age between men and women. Ten‐year probability was standardized to that of men and women from Sweden (set at 1.0). There was a 15‐fold range in 10‐year probability from 1.24 in Norway to 0.08 in Chile. Countries were categorized by 10‐year probabilities comprising very high risk (Norway, Iceland, Sweden, Denmark, and the United States), high risk (China [Taiwan {TW}], Germany, Switzerland, Finland, Greece, Canada, The Netherlands, Hungary, Singapore, Italy, United Kingdom, Kuwait, Australia, and Portugal), medium risk (China [Hong Kong {HK}], France, Japan, Spain, Argentina, and China), and low risk (Turkey, Korea, Venezuela, and Chile). The categorization of hip fracture probabilities can be used to adjust intervention thresholds based on age, sex, and relative risk from a reference population such as Sweden. |
format |
Article in Journal/Newspaper |
author |
Kanis, John A. Johnell, Olof De Laet, Chris Jonsson, Bengt Oden, Anders Ogelsby, Alan K. |
author_facet |
Kanis, John A. Johnell, Olof De Laet, Chris Jonsson, Bengt Oden, Anders Ogelsby, Alan K. |
author_sort |
Kanis, John A. |
title |
International Variations in Hip Fracture Probabilities: Implications for Risk Assessment |
title_short |
International Variations in Hip Fracture Probabilities: Implications for Risk Assessment |
title_full |
International Variations in Hip Fracture Probabilities: Implications for Risk Assessment |
title_fullStr |
International Variations in Hip Fracture Probabilities: Implications for Risk Assessment |
title_full_unstemmed |
International Variations in Hip Fracture Probabilities: Implications for Risk Assessment |
title_sort |
international variations in hip fracture probabilities: implications for risk assessment |
publisher |
Wiley |
publishDate |
2002 |
url |
http://dx.doi.org/10.1359/jbmr.2002.17.7.1237 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1359%2Fjbmr.2002.17.7.1237 https://onlinelibrary.wiley.com/doi/pdf/10.1359/jbmr.2002.17.7.1237 https://onlinelibrary.wiley.com/doi/full-xml/10.1359/jbmr.2002.17.7.1237 |
geographic |
Canada Norway Argentina |
geographic_facet |
Canada Norway Argentina |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Journal of Bone and Mineral Research volume 17, issue 7, page 1237-1244 ISSN 0884-0431 1523-4681 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1359/jbmr.2002.17.7.1237 |
container_title |
Journal of Bone and Mineral Research |
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17 |
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7 |
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1237 |
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1244 |
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