Dietary risk factors for inflammatory bowel diseases in a high‐risk population: Results from the Faroese IBD study
Background The Faroe Islands currently have the highest recorded inflammatory bowel disease (IBD) incidence in the world. Objective This study investigated environmental risk factors for IBD in the Faroese population. Methods Environmental exposure data including lifestyle risk factors and neurotoxi...
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Online Access: | http://dx.doi.org/10.1177/2050640619852244 https://onlinelibrary.wiley.com/doi/pdf/10.1177/2050640619852244 https://onlinelibrary.wiley.com/doi/full-xml/10.1177/2050640619852244 |
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crwiley:10.1177/2050640619852244 2024-10-20T14:08:33+00:00 Dietary risk factors for inflammatory bowel diseases in a high‐risk population: Results from the Faroese IBD study Hammer, T Lophaven, S Nymand Nielsen, K Rubek Petersen, M Skaalum Munkholm, P Weihe, P Burisch, J Lynge, E Granskingarráðið European Crohn's and Colitis Organisation Aage & Johanne Louis-Hansens Foundation Danish Colitis-Crohn Patients Organisation Beckett Foundation Faroese Research Council 2019 http://dx.doi.org/10.1177/2050640619852244 https://onlinelibrary.wiley.com/doi/pdf/10.1177/2050640619852244 https://onlinelibrary.wiley.com/doi/full-xml/10.1177/2050640619852244 en eng Wiley http://creativecommons.org/licenses/by-nc/4.0/ http://journals.sagepub.com/page/policies/text-and-data-mining-license United European Gastroenterology Journal volume 7, issue 7, page 924-932 ISSN 2050-6406 2050-6414 journal-article 2019 crwiley https://doi.org/10.1177/2050640619852244 2024-09-23T04:36:09Z Background The Faroe Islands currently have the highest recorded inflammatory bowel disease (IBD) incidence in the world. Objective This study investigated environmental risk factors for IBD in the Faroese population. Methods Environmental exposure data including lifestyle risk factors and neurotoxicants collected for over 30 years were retrieved from the Children's Health and the Environment in the Faroes (CHEF) cohorts including mainly mother–child pairs, with exposure data collected from pregnant mothers. For lifestyle risk factors, the incidence of IBD and ulcerative colitis (UC) was calculated as the rate ratio (RR) with 95% confidence intervals (CI) in exposed versus non‐exposed persons. For neurotoxicants RR was calculated for persons with high versus low exposure. Results Six cohorts included 5698 persons with complete follow‐up data and at least one exposure, and 37 were diagnosed with IBD. For pilot whale/blubber, the RR was 1.02 (95% CI, 0.48–2.18); RR of 1.01 for fish (95% CI, 0.35–2.91); and of the pollutants studied, a statistical significantly increased risk was found for 1,1,1,‐trichloro‐2,2‐bis‐(p‐chlorophenyl) ethane (p,p'‐DDT); RR 3.04 (95% CI, 1.12–8.30). RRs were 1.96 (95% CI, 1.03–3.73) for smoking and 1.10 (95% CI, 0.55–2.19) for alcohol intake. Conclusion The high IBD incidence is unlikely to be caused by special dietary habits or by environmental pollutants. Article in Journal/Newspaper Faroe Islands Faroes Wiley Online Library Faroe Islands United European Gastroenterology Journal 7 7 924 932 |
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Wiley Online Library |
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crwiley |
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English |
description |
Background The Faroe Islands currently have the highest recorded inflammatory bowel disease (IBD) incidence in the world. Objective This study investigated environmental risk factors for IBD in the Faroese population. Methods Environmental exposure data including lifestyle risk factors and neurotoxicants collected for over 30 years were retrieved from the Children's Health and the Environment in the Faroes (CHEF) cohorts including mainly mother–child pairs, with exposure data collected from pregnant mothers. For lifestyle risk factors, the incidence of IBD and ulcerative colitis (UC) was calculated as the rate ratio (RR) with 95% confidence intervals (CI) in exposed versus non‐exposed persons. For neurotoxicants RR was calculated for persons with high versus low exposure. Results Six cohorts included 5698 persons with complete follow‐up data and at least one exposure, and 37 were diagnosed with IBD. For pilot whale/blubber, the RR was 1.02 (95% CI, 0.48–2.18); RR of 1.01 for fish (95% CI, 0.35–2.91); and of the pollutants studied, a statistical significantly increased risk was found for 1,1,1,‐trichloro‐2,2‐bis‐(p‐chlorophenyl) ethane (p,p'‐DDT); RR 3.04 (95% CI, 1.12–8.30). RRs were 1.96 (95% CI, 1.03–3.73) for smoking and 1.10 (95% CI, 0.55–2.19) for alcohol intake. Conclusion The high IBD incidence is unlikely to be caused by special dietary habits or by environmental pollutants. |
author2 |
Granskingarráðið European Crohn's and Colitis Organisation Aage & Johanne Louis-Hansens Foundation Danish Colitis-Crohn Patients Organisation Beckett Foundation Faroese Research Council |
format |
Article in Journal/Newspaper |
author |
Hammer, T Lophaven, S Nymand Nielsen, K Rubek Petersen, M Skaalum Munkholm, P Weihe, P Burisch, J Lynge, E |
spellingShingle |
Hammer, T Lophaven, S Nymand Nielsen, K Rubek Petersen, M Skaalum Munkholm, P Weihe, P Burisch, J Lynge, E Dietary risk factors for inflammatory bowel diseases in a high‐risk population: Results from the Faroese IBD study |
author_facet |
Hammer, T Lophaven, S Nymand Nielsen, K Rubek Petersen, M Skaalum Munkholm, P Weihe, P Burisch, J Lynge, E |
author_sort |
Hammer, T |
title |
Dietary risk factors for inflammatory bowel diseases in a high‐risk population: Results from the Faroese IBD study |
title_short |
Dietary risk factors for inflammatory bowel diseases in a high‐risk population: Results from the Faroese IBD study |
title_full |
Dietary risk factors for inflammatory bowel diseases in a high‐risk population: Results from the Faroese IBD study |
title_fullStr |
Dietary risk factors for inflammatory bowel diseases in a high‐risk population: Results from the Faroese IBD study |
title_full_unstemmed |
Dietary risk factors for inflammatory bowel diseases in a high‐risk population: Results from the Faroese IBD study |
title_sort |
dietary risk factors for inflammatory bowel diseases in a high‐risk population: results from the faroese ibd study |
publisher |
Wiley |
publishDate |
2019 |
url |
http://dx.doi.org/10.1177/2050640619852244 https://onlinelibrary.wiley.com/doi/pdf/10.1177/2050640619852244 https://onlinelibrary.wiley.com/doi/full-xml/10.1177/2050640619852244 |
geographic |
Faroe Islands |
geographic_facet |
Faroe Islands |
genre |
Faroe Islands Faroes |
genre_facet |
Faroe Islands Faroes |
op_source |
United European Gastroenterology Journal volume 7, issue 7, page 924-932 ISSN 2050-6406 2050-6414 |
op_rights |
http://creativecommons.org/licenses/by-nc/4.0/ http://journals.sagepub.com/page/policies/text-and-data-mining-license |
op_doi |
https://doi.org/10.1177/2050640619852244 |
container_title |
United European Gastroenterology Journal |
container_volume |
7 |
container_issue |
7 |
container_start_page |
924 |
op_container_end_page |
932 |
_version_ |
1813447743328223232 |