Community‐Associated Methicillin‐Resistant Staphylococcus aureus in Northwest Ontario: A Five‐Year Report of Incidence and Antibiotic Resistance
BACKGROUND: The incidence of community‐associated methicillin‐resistant Staphylococcus aureus (CA‐MRSA) is traditionally high in remote areas of Canada with large Aboriginal populations. Northwestern Ontario is home to 28,000 First Nations people in more than 30 remote communities; rates of CA‐MRSA...
Published in: | Canadian Journal of Infectious Diseases and Medical Microbiology |
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Online Access: | http://dx.doi.org/10.1155/2013/169409 http://downloads.hindawi.com/journals/cjidmm/2013/169409.pdf https://onlinelibrary.wiley.com/doi/pdf/10.1155/2013/169409 |
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crwiley:10.1155/2013/169409 2024-09-15T18:06:46+00:00 Community‐Associated Methicillin‐Resistant Staphylococcus aureus in Northwest Ontario: A Five‐Year Report of Incidence and Antibiotic Resistance Muileboom, Jill Hamilton, Marsha Parent, Karen Makahnouk, Donna Kirlew, Michael Saginur, Raphael Lam, Freda Kelly, Len 2013 http://dx.doi.org/10.1155/2013/169409 http://downloads.hindawi.com/journals/cjidmm/2013/169409.pdf https://onlinelibrary.wiley.com/doi/pdf/10.1155/2013/169409 en eng Wiley http://creativecommons.org/licenses/by/4.0/ Canadian Journal of Infectious Diseases and Medical Microbiology volume 24, issue 2 ISSN 1712-9532 1918-1493 journal-article 2013 crwiley https://doi.org/10.1155/2013/169409 2024-08-13T04:17:33Z BACKGROUND: The incidence of community‐associated methicillin‐resistant Staphylococcus aureus (CA‐MRSA) is traditionally high in remote areas of Canada with large Aboriginal populations. Northwestern Ontario is home to 28,000 First Nations people in more than 30 remote communities; rates of CA‐MRSA are unknown. OBJECTIVE: To determine the CA‐MRSA rates and antibiotic susceptibilities in this region. METHODS: A five‐year review of laboratory and patient CA‐MRSA data and antibiotic susceptibility was undertaken. RESULTS: In 2012, 56% of S aureus isolates were CA‐MRSA strains, an increase from 31% in 2008 (P=0.06). Reinfection rates have been increasing faster than new cases and, currrently, 25% of infections are reinfections. CA‐MRSA isolates continue to be susceptible to many common antibiotics (nearly 100%), particularly trimethoprim/sulfamethoxazole, clindamycin and tetracycline. Erythromycin susceptibility stands at 58%. DISCUSSION: Rates of CA‐MRSA, as a percentage of all S aureus isolates, were higher than those reported in other primary care series. The infection rate per 100,000 is one the highest reported in Canada. Antibiotic susceptibilities were unchanged during the study period; the 99% susceptibility rate to clindamycin differs from a 2010 Vancouver (British Columbia) study that reported only a 79% susceptibility to this antibiotic. CONCLUSION: There are very high rates of CA‐MRSA infections in northwestern Ontario. Disease surveillance and ongoing attention to antibiotic resistance is important in understanding the changing profile of MRSA infections. Social determinants of health, specifically improved housing and sanitation, remain important regional issues. Article in Journal/Newspaper First Nations Wiley Online Library Canadian Journal of Infectious Diseases and Medical Microbiology 24 2 |
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BACKGROUND: The incidence of community‐associated methicillin‐resistant Staphylococcus aureus (CA‐MRSA) is traditionally high in remote areas of Canada with large Aboriginal populations. Northwestern Ontario is home to 28,000 First Nations people in more than 30 remote communities; rates of CA‐MRSA are unknown. OBJECTIVE: To determine the CA‐MRSA rates and antibiotic susceptibilities in this region. METHODS: A five‐year review of laboratory and patient CA‐MRSA data and antibiotic susceptibility was undertaken. RESULTS: In 2012, 56% of S aureus isolates were CA‐MRSA strains, an increase from 31% in 2008 (P=0.06). Reinfection rates have been increasing faster than new cases and, currrently, 25% of infections are reinfections. CA‐MRSA isolates continue to be susceptible to many common antibiotics (nearly 100%), particularly trimethoprim/sulfamethoxazole, clindamycin and tetracycline. Erythromycin susceptibility stands at 58%. DISCUSSION: Rates of CA‐MRSA, as a percentage of all S aureus isolates, were higher than those reported in other primary care series. The infection rate per 100,000 is one the highest reported in Canada. Antibiotic susceptibilities were unchanged during the study period; the 99% susceptibility rate to clindamycin differs from a 2010 Vancouver (British Columbia) study that reported only a 79% susceptibility to this antibiotic. CONCLUSION: There are very high rates of CA‐MRSA infections in northwestern Ontario. Disease surveillance and ongoing attention to antibiotic resistance is important in understanding the changing profile of MRSA infections. Social determinants of health, specifically improved housing and sanitation, remain important regional issues. |
format |
Article in Journal/Newspaper |
author |
Muileboom, Jill Hamilton, Marsha Parent, Karen Makahnouk, Donna Kirlew, Michael Saginur, Raphael Lam, Freda Kelly, Len |
spellingShingle |
Muileboom, Jill Hamilton, Marsha Parent, Karen Makahnouk, Donna Kirlew, Michael Saginur, Raphael Lam, Freda Kelly, Len Community‐Associated Methicillin‐Resistant Staphylococcus aureus in Northwest Ontario: A Five‐Year Report of Incidence and Antibiotic Resistance |
author_facet |
Muileboom, Jill Hamilton, Marsha Parent, Karen Makahnouk, Donna Kirlew, Michael Saginur, Raphael Lam, Freda Kelly, Len |
author_sort |
Muileboom, Jill |
title |
Community‐Associated Methicillin‐Resistant Staphylococcus aureus in Northwest Ontario: A Five‐Year Report of Incidence and Antibiotic Resistance |
title_short |
Community‐Associated Methicillin‐Resistant Staphylococcus aureus in Northwest Ontario: A Five‐Year Report of Incidence and Antibiotic Resistance |
title_full |
Community‐Associated Methicillin‐Resistant Staphylococcus aureus in Northwest Ontario: A Five‐Year Report of Incidence and Antibiotic Resistance |
title_fullStr |
Community‐Associated Methicillin‐Resistant Staphylococcus aureus in Northwest Ontario: A Five‐Year Report of Incidence and Antibiotic Resistance |
title_full_unstemmed |
Community‐Associated Methicillin‐Resistant Staphylococcus aureus in Northwest Ontario: A Five‐Year Report of Incidence and Antibiotic Resistance |
title_sort |
community‐associated methicillin‐resistant staphylococcus aureus in northwest ontario: a five‐year report of incidence and antibiotic resistance |
publisher |
Wiley |
publishDate |
2013 |
url |
http://dx.doi.org/10.1155/2013/169409 http://downloads.hindawi.com/journals/cjidmm/2013/169409.pdf https://onlinelibrary.wiley.com/doi/pdf/10.1155/2013/169409 |
genre |
First Nations |
genre_facet |
First Nations |
op_source |
Canadian Journal of Infectious Diseases and Medical Microbiology volume 24, issue 2 ISSN 1712-9532 1918-1493 |
op_rights |
http://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1155/2013/169409 |
container_title |
Canadian Journal of Infectious Diseases and Medical Microbiology |
container_volume |
24 |
container_issue |
2 |
_version_ |
1810444148375814144 |