Characterization of the cardiac phospholipidome of small cetaceans provides adaptational insight and a foundation for indirect population health screening
Abstract The maintenance of a tightly regulated heart lipidome is a general hallmark of mammal health. However, in the case of cetaceans, heart tissue lipid composition remains obscure. This work represents a first in‐depth state‐of‐the‐art characterization of the lipid content of small cetacean hea...
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Online Access: | http://dx.doi.org/10.1111/mms.12823 https://onlinelibrary.wiley.com/doi/pdf/10.1111/mms.12823 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/mms.12823 |
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crwiley:10.1111/mms.12823 2024-04-28T08:36:16+00:00 Characterization of the cardiac phospholipidome of small cetaceans provides adaptational insight and a foundation for indirect population health screening Monteiro, João P. Maciel, Elisabete Maia, Rita Pereira, Andreia T. Calado, Ricardo Domingues, Pedro Melo, Tânia Eira, Catarina Domingues, M. Rosário 2021 http://dx.doi.org/10.1111/mms.12823 https://onlinelibrary.wiley.com/doi/pdf/10.1111/mms.12823 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/mms.12823 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Marine Mammal Science volume 37, issue 4, page 1406-1427 ISSN 0824-0469 1748-7692 Aquatic Science Ecology, Evolution, Behavior and Systematics journal-article 2021 crwiley https://doi.org/10.1111/mms.12823 2024-04-02T08:44:09Z Abstract The maintenance of a tightly regulated heart lipidome is a general hallmark of mammal health. However, in the case of cetaceans, heart tissue lipid composition remains obscure. This work represents a first in‐depth state‐of‐the‐art characterization of the lipid content of small cetacean hearts, namely those of Delphinus delphis , Phocoena phocoena , and Stenella coeruleoalba . Phospholipid classes identified were similar to those found in terrestrial mammals. Regarding fatty acid profiles, they revealed a much higher n ‐3 fatty acid content than that reported for terrestrial counterparts. Phospholipidome characterization allowed identification of 198 lipid species, including phospholipids, lysophospholipids, and sphingomyelins, generally characterized by a high content of species with esterified n ‐3 fatty acids. The cardiac lipid profile of the three cetacean species is similar in terms of lipid classes, fatty acids, and even molecular lipid species present. However, quantitative differences suggest a divergence of S. coeruleoalba from the other species in terms of fatty acid and phospholipid profile. The identified differences regarding terrestrial counterparts will contribute to better understanding the details of small cetacean cardiac physiology. Moreover, the characterization of cardiac phospholipidome may represent an opportunity to establish lipidomic‐based practical tools to reliably and reproducibly assess small cetacean health population status by remote sampling. Article in Journal/Newspaper Phocoena phocoena Wiley Online Library Marine Mammal Science 37 4 1406 1427 |
institution |
Open Polar |
collection |
Wiley Online Library |
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crwiley |
language |
English |
topic |
Aquatic Science Ecology, Evolution, Behavior and Systematics |
spellingShingle |
Aquatic Science Ecology, Evolution, Behavior and Systematics Monteiro, João P. Maciel, Elisabete Maia, Rita Pereira, Andreia T. Calado, Ricardo Domingues, Pedro Melo, Tânia Eira, Catarina Domingues, M. Rosário Characterization of the cardiac phospholipidome of small cetaceans provides adaptational insight and a foundation for indirect population health screening |
topic_facet |
Aquatic Science Ecology, Evolution, Behavior and Systematics |
description |
Abstract The maintenance of a tightly regulated heart lipidome is a general hallmark of mammal health. However, in the case of cetaceans, heart tissue lipid composition remains obscure. This work represents a first in‐depth state‐of‐the‐art characterization of the lipid content of small cetacean hearts, namely those of Delphinus delphis , Phocoena phocoena , and Stenella coeruleoalba . Phospholipid classes identified were similar to those found in terrestrial mammals. Regarding fatty acid profiles, they revealed a much higher n ‐3 fatty acid content than that reported for terrestrial counterparts. Phospholipidome characterization allowed identification of 198 lipid species, including phospholipids, lysophospholipids, and sphingomyelins, generally characterized by a high content of species with esterified n ‐3 fatty acids. The cardiac lipid profile of the three cetacean species is similar in terms of lipid classes, fatty acids, and even molecular lipid species present. However, quantitative differences suggest a divergence of S. coeruleoalba from the other species in terms of fatty acid and phospholipid profile. The identified differences regarding terrestrial counterparts will contribute to better understanding the details of small cetacean cardiac physiology. Moreover, the characterization of cardiac phospholipidome may represent an opportunity to establish lipidomic‐based practical tools to reliably and reproducibly assess small cetacean health population status by remote sampling. |
format |
Article in Journal/Newspaper |
author |
Monteiro, João P. Maciel, Elisabete Maia, Rita Pereira, Andreia T. Calado, Ricardo Domingues, Pedro Melo, Tânia Eira, Catarina Domingues, M. Rosário |
author_facet |
Monteiro, João P. Maciel, Elisabete Maia, Rita Pereira, Andreia T. Calado, Ricardo Domingues, Pedro Melo, Tânia Eira, Catarina Domingues, M. Rosário |
author_sort |
Monteiro, João P. |
title |
Characterization of the cardiac phospholipidome of small cetaceans provides adaptational insight and a foundation for indirect population health screening |
title_short |
Characterization of the cardiac phospholipidome of small cetaceans provides adaptational insight and a foundation for indirect population health screening |
title_full |
Characterization of the cardiac phospholipidome of small cetaceans provides adaptational insight and a foundation for indirect population health screening |
title_fullStr |
Characterization of the cardiac phospholipidome of small cetaceans provides adaptational insight and a foundation for indirect population health screening |
title_full_unstemmed |
Characterization of the cardiac phospholipidome of small cetaceans provides adaptational insight and a foundation for indirect population health screening |
title_sort |
characterization of the cardiac phospholipidome of small cetaceans provides adaptational insight and a foundation for indirect population health screening |
publisher |
Wiley |
publishDate |
2021 |
url |
http://dx.doi.org/10.1111/mms.12823 https://onlinelibrary.wiley.com/doi/pdf/10.1111/mms.12823 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/mms.12823 |
genre |
Phocoena phocoena |
genre_facet |
Phocoena phocoena |
op_source |
Marine Mammal Science volume 37, issue 4, page 1406-1427 ISSN 0824-0469 1748-7692 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/mms.12823 |
container_title |
Marine Mammal Science |
container_volume |
37 |
container_issue |
4 |
container_start_page |
1406 |
op_container_end_page |
1427 |
_version_ |
1797568097124614144 |