Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge
Abstract The Bering Land Bridge (BLB) last connected Eurasia and North America during the Late Pleistocene. Although the BLB would have enabled transfers of terrestrial biota in both directions, it also acted as an ecological filter whose permeability varied considerably over time. Here we explore t...
Published in: | Molecular Ecology |
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Online Access: | http://dx.doi.org/10.1111/mec.15977 https://onlinelibrary.wiley.com/doi/pdf/10.1111/mec.15977 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/mec.15977 |
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crwiley:10.1111/mec.15977 2024-09-15T17:59:19+00:00 Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge Vershinina, Alisa O. Heintzman, Peter D. Froese, Duane G. Zazula, Grant Cassatt‐Johnstone, Molly Dalén, Love Der Sarkissian, Clio Dunn, Shelby G. Ermini, Luca Gamba, Cristina Groves, Pamela Kapp, Joshua D. Mann, Daniel H. Seguin‐Orlando, Andaine Southon, John Stiller, Mathias Wooller, Matthew J. Baryshnikov, Gennady Gimranov, Dmitry Scott, Eric Hall, Elizabeth Hewitson, Susan Kirillova, Irina Kosintsev, Pavel Shidlovsky, Fedor Tong, Hao‐Wen Tiunov, Mikhail P. Vartanyan, Sergey Orlando, Ludovic Corbett‐Detig, Russell MacPhee, Ross D. Shapiro, Beth Uppsala Multidisciplinary Center for Advanced Computational Science Knut och Alice Wallenbergs Stiftelse U.S. Bureau of Land Management Natural Sciences and Engineering Research Council of Canada Svenska Forskningsrådet Formas University of California, Santa Cruz Science for Life Laboratory Russian Foundation for Basic Research 2021 http://dx.doi.org/10.1111/mec.15977 https://onlinelibrary.wiley.com/doi/pdf/10.1111/mec.15977 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/mec.15977 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Molecular Ecology volume 30, issue 23, page 6144-6161 ISSN 0962-1083 1365-294X journal-article 2021 crwiley https://doi.org/10.1111/mec.15977 2024-09-03T04:26:49Z Abstract The Bering Land Bridge (BLB) last connected Eurasia and North America during the Late Pleistocene. Although the BLB would have enabled transfers of terrestrial biota in both directions, it also acted as an ecological filter whose permeability varied considerably over time. Here we explore the possible impacts of this ecological corridor on genetic diversity within, and connectivity among, populations of a once wide‐ranging group, the caballine horses ( Equus spp.). Using a panel of 187 mitochondrial and eight nuclear genomes recovered from present‐day and extinct caballine horses sampled across the Holarctic, we found that Eurasian horse populations initially diverged from those in North America, their ancestral continent, around 1.0–0.8 million years ago. Subsequent to this split our mitochondrial DNA analysis identified two bidirectional long‐range dispersals across the BLB ~875–625 and ~200–50 thousand years ago, during the Middle and Late Pleistocene. Whole genome analysis indicated low levels of gene flow between North American and Eurasian horse populations, which probably occurred as a result of these inferred dispersals. Nonetheless, mitochondrial and nuclear diversity of caballine horse populations retained strong phylogeographical structuring. Our results suggest that barriers to gene flow, currently unidentified but possibly related to habitat distribution across Beringia or ongoing evolutionary divergence, played an important role in shaping the early genetic history of caballine horses, including the ancestors of living horses within Equus ferus . Article in Journal/Newspaper Bering Land Bridge Beringia Wiley Online Library Molecular Ecology |
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Open Polar |
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Wiley Online Library |
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crwiley |
language |
English |
description |
Abstract The Bering Land Bridge (BLB) last connected Eurasia and North America during the Late Pleistocene. Although the BLB would have enabled transfers of terrestrial biota in both directions, it also acted as an ecological filter whose permeability varied considerably over time. Here we explore the possible impacts of this ecological corridor on genetic diversity within, and connectivity among, populations of a once wide‐ranging group, the caballine horses ( Equus spp.). Using a panel of 187 mitochondrial and eight nuclear genomes recovered from present‐day and extinct caballine horses sampled across the Holarctic, we found that Eurasian horse populations initially diverged from those in North America, their ancestral continent, around 1.0–0.8 million years ago. Subsequent to this split our mitochondrial DNA analysis identified two bidirectional long‐range dispersals across the BLB ~875–625 and ~200–50 thousand years ago, during the Middle and Late Pleistocene. Whole genome analysis indicated low levels of gene flow between North American and Eurasian horse populations, which probably occurred as a result of these inferred dispersals. Nonetheless, mitochondrial and nuclear diversity of caballine horse populations retained strong phylogeographical structuring. Our results suggest that barriers to gene flow, currently unidentified but possibly related to habitat distribution across Beringia or ongoing evolutionary divergence, played an important role in shaping the early genetic history of caballine horses, including the ancestors of living horses within Equus ferus . |
author2 |
Uppsala Multidisciplinary Center for Advanced Computational Science Knut och Alice Wallenbergs Stiftelse U.S. Bureau of Land Management Natural Sciences and Engineering Research Council of Canada Svenska Forskningsrådet Formas University of California, Santa Cruz Science for Life Laboratory Russian Foundation for Basic Research |
format |
Article in Journal/Newspaper |
author |
Vershinina, Alisa O. Heintzman, Peter D. Froese, Duane G. Zazula, Grant Cassatt‐Johnstone, Molly Dalén, Love Der Sarkissian, Clio Dunn, Shelby G. Ermini, Luca Gamba, Cristina Groves, Pamela Kapp, Joshua D. Mann, Daniel H. Seguin‐Orlando, Andaine Southon, John Stiller, Mathias Wooller, Matthew J. Baryshnikov, Gennady Gimranov, Dmitry Scott, Eric Hall, Elizabeth Hewitson, Susan Kirillova, Irina Kosintsev, Pavel Shidlovsky, Fedor Tong, Hao‐Wen Tiunov, Mikhail P. Vartanyan, Sergey Orlando, Ludovic Corbett‐Detig, Russell MacPhee, Ross D. Shapiro, Beth |
spellingShingle |
Vershinina, Alisa O. Heintzman, Peter D. Froese, Duane G. Zazula, Grant Cassatt‐Johnstone, Molly Dalén, Love Der Sarkissian, Clio Dunn, Shelby G. Ermini, Luca Gamba, Cristina Groves, Pamela Kapp, Joshua D. Mann, Daniel H. Seguin‐Orlando, Andaine Southon, John Stiller, Mathias Wooller, Matthew J. Baryshnikov, Gennady Gimranov, Dmitry Scott, Eric Hall, Elizabeth Hewitson, Susan Kirillova, Irina Kosintsev, Pavel Shidlovsky, Fedor Tong, Hao‐Wen Tiunov, Mikhail P. Vartanyan, Sergey Orlando, Ludovic Corbett‐Detig, Russell MacPhee, Ross D. Shapiro, Beth Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge |
author_facet |
Vershinina, Alisa O. Heintzman, Peter D. Froese, Duane G. Zazula, Grant Cassatt‐Johnstone, Molly Dalén, Love Der Sarkissian, Clio Dunn, Shelby G. Ermini, Luca Gamba, Cristina Groves, Pamela Kapp, Joshua D. Mann, Daniel H. Seguin‐Orlando, Andaine Southon, John Stiller, Mathias Wooller, Matthew J. Baryshnikov, Gennady Gimranov, Dmitry Scott, Eric Hall, Elizabeth Hewitson, Susan Kirillova, Irina Kosintsev, Pavel Shidlovsky, Fedor Tong, Hao‐Wen Tiunov, Mikhail P. Vartanyan, Sergey Orlando, Ludovic Corbett‐Detig, Russell MacPhee, Ross D. Shapiro, Beth |
author_sort |
Vershinina, Alisa O. |
title |
Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge |
title_short |
Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge |
title_full |
Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge |
title_fullStr |
Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge |
title_full_unstemmed |
Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge |
title_sort |
ancient horse genomes reveal the timing and extent of dispersals across the bering land bridge |
publisher |
Wiley |
publishDate |
2021 |
url |
http://dx.doi.org/10.1111/mec.15977 https://onlinelibrary.wiley.com/doi/pdf/10.1111/mec.15977 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/mec.15977 |
genre |
Bering Land Bridge Beringia |
genre_facet |
Bering Land Bridge Beringia |
op_source |
Molecular Ecology volume 30, issue 23, page 6144-6161 ISSN 0962-1083 1365-294X |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/mec.15977 |
container_title |
Molecular Ecology |
_version_ |
1810436401259347968 |