Latitudinal divergence in a widespread amphibian: Contrasting patterns of neutral and adaptive genomic variation
Abstract Stochastic effects from demographic processes and selection are expected to shape the distribution of genetic variation in spatially heterogeneous environments. As the amount of genetic variation is central for long‐term persistence of populations, understanding how these processes affect v...
Published in: | Molecular Ecology |
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Online Access: | http://dx.doi.org/10.1111/mec.15132 https://onlinelibrary.wiley.com/doi/pdf/10.1111/mec.15132 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/mec.15132 |
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crwiley:10.1111/mec.15132 2024-04-14T08:16:42+00:00 Latitudinal divergence in a widespread amphibian: Contrasting patterns of neutral and adaptive genomic variation Rödin‐Mörch, Patrik Luquet, Emilien Meyer‐Lucht, Yvonne Richter‐Boix, Alex Höglund, Jacob Laurila, Anssi Vetenskapsrådet Carl Tryggers Stiftelse för Vetenskaplig Forskning 2019 http://dx.doi.org/10.1111/mec.15132 https://onlinelibrary.wiley.com/doi/pdf/10.1111/mec.15132 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/mec.15132 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Molecular Ecology volume 28, issue 12, page 2996-3011 ISSN 0962-1083 1365-294X Genetics Ecology, Evolution, Behavior and Systematics journal-article 2019 crwiley https://doi.org/10.1111/mec.15132 2024-03-19T10:54:59Z Abstract Stochastic effects from demographic processes and selection are expected to shape the distribution of genetic variation in spatially heterogeneous environments. As the amount of genetic variation is central for long‐term persistence of populations, understanding how these processes affect variation over large‐scale geographical gradients is pivotal. We investigated the distribution of neutral and putatively adaptive genetic variation, and reconstructed demographic history in the moor frog ( Rana arvalis ) using 136 individuals from 15 populations along a 1,700‐km latitudinal gradient from northern Germany to northern Sweden. Using double digest restriction‐site associated DNA sequencing we obtained 27,590 single nucleotide polymorphisms (SNPs), and identified differentiation outliers and SNPs associated with growing season length. The populations grouped into a southern and a northern cluster, representing two phylogeographical lineages from different post‐glacial colonization routes. Hybrid index estimation and demographic model selection showed strong support for a southern and northern lineage and evidence of gene flow between regions located on each side of a contact zone. However, patterns of past gene flow over the contact zone differed between neutral and putatively adaptive SNPs. While neutral nucleotide diversity was higher along the southern than the northern part of the gradient, nucleotide diversity in differentiation outliers showed the opposite pattern, suggesting differences in the relative strength of selection and drift along the gradient. Variation associated with growing season length decreased with latitude along the southern part of the gradient, but not along the northern part where variation was lower, suggesting stronger climate‐mediated selection in the north. Outlier SNPs included loci involved in immunity and developmental processes. Article in Journal/Newspaper Northern Sweden Wiley Online Library Molecular Ecology 28 12 2996 3011 |
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English |
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Genetics Ecology, Evolution, Behavior and Systematics |
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Genetics Ecology, Evolution, Behavior and Systematics Rödin‐Mörch, Patrik Luquet, Emilien Meyer‐Lucht, Yvonne Richter‐Boix, Alex Höglund, Jacob Laurila, Anssi Latitudinal divergence in a widespread amphibian: Contrasting patterns of neutral and adaptive genomic variation |
topic_facet |
Genetics Ecology, Evolution, Behavior and Systematics |
description |
Abstract Stochastic effects from demographic processes and selection are expected to shape the distribution of genetic variation in spatially heterogeneous environments. As the amount of genetic variation is central for long‐term persistence of populations, understanding how these processes affect variation over large‐scale geographical gradients is pivotal. We investigated the distribution of neutral and putatively adaptive genetic variation, and reconstructed demographic history in the moor frog ( Rana arvalis ) using 136 individuals from 15 populations along a 1,700‐km latitudinal gradient from northern Germany to northern Sweden. Using double digest restriction‐site associated DNA sequencing we obtained 27,590 single nucleotide polymorphisms (SNPs), and identified differentiation outliers and SNPs associated with growing season length. The populations grouped into a southern and a northern cluster, representing two phylogeographical lineages from different post‐glacial colonization routes. Hybrid index estimation and demographic model selection showed strong support for a southern and northern lineage and evidence of gene flow between regions located on each side of a contact zone. However, patterns of past gene flow over the contact zone differed between neutral and putatively adaptive SNPs. While neutral nucleotide diversity was higher along the southern than the northern part of the gradient, nucleotide diversity in differentiation outliers showed the opposite pattern, suggesting differences in the relative strength of selection and drift along the gradient. Variation associated with growing season length decreased with latitude along the southern part of the gradient, but not along the northern part where variation was lower, suggesting stronger climate‐mediated selection in the north. Outlier SNPs included loci involved in immunity and developmental processes. |
author2 |
Vetenskapsrådet Carl Tryggers Stiftelse för Vetenskaplig Forskning |
format |
Article in Journal/Newspaper |
author |
Rödin‐Mörch, Patrik Luquet, Emilien Meyer‐Lucht, Yvonne Richter‐Boix, Alex Höglund, Jacob Laurila, Anssi |
author_facet |
Rödin‐Mörch, Patrik Luquet, Emilien Meyer‐Lucht, Yvonne Richter‐Boix, Alex Höglund, Jacob Laurila, Anssi |
author_sort |
Rödin‐Mörch, Patrik |
title |
Latitudinal divergence in a widespread amphibian: Contrasting patterns of neutral and adaptive genomic variation |
title_short |
Latitudinal divergence in a widespread amphibian: Contrasting patterns of neutral and adaptive genomic variation |
title_full |
Latitudinal divergence in a widespread amphibian: Contrasting patterns of neutral and adaptive genomic variation |
title_fullStr |
Latitudinal divergence in a widespread amphibian: Contrasting patterns of neutral and adaptive genomic variation |
title_full_unstemmed |
Latitudinal divergence in a widespread amphibian: Contrasting patterns of neutral and adaptive genomic variation |
title_sort |
latitudinal divergence in a widespread amphibian: contrasting patterns of neutral and adaptive genomic variation |
publisher |
Wiley |
publishDate |
2019 |
url |
http://dx.doi.org/10.1111/mec.15132 https://onlinelibrary.wiley.com/doi/pdf/10.1111/mec.15132 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/mec.15132 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_source |
Molecular Ecology volume 28, issue 12, page 2996-3011 ISSN 0962-1083 1365-294X |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/mec.15132 |
container_title |
Molecular Ecology |
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28 |
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12 |
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2996 |
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3011 |
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1796315432813068288 |