First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture
Abstract ISAV is the causative agent of the infectious salmon anaemia (ISA), a disease listed by the OIE that has caused important economic losses to the Atlantic salmon ( Salmo salar ) industry. ISAV variants are identified as pathogenic or non‐pathogenic based on the presence or absence of a delet...
Published in: | Journal of Fish Diseases |
---|---|
Main Authors: | , , , , , |
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
2021
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1111/jfd.13556 https://onlinelibrary.wiley.com/doi/pdf/10.1111/jfd.13556 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/jfd.13556 |
id |
crwiley:10.1111/jfd.13556 |
---|---|
record_format |
openpolar |
spelling |
crwiley:10.1111/jfd.13556 2024-09-15T17:56:22+00:00 First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture Ditlecadet, D. Gautreau, C. Boston, L. Liston, R. Johnsen, E. Gagné, N. Fisheries and Oceans Canada 2021 http://dx.doi.org/10.1111/jfd.13556 https://onlinelibrary.wiley.com/doi/pdf/10.1111/jfd.13556 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/jfd.13556 en eng Wiley http://creativecommons.org/licenses/by-nc-nd/4.0/ Journal of Fish Diseases volume 45, issue 3, page 479-483 ISSN 0140-7775 1365-2761 journal-article 2021 crwiley https://doi.org/10.1111/jfd.13556 2024-07-30T04:19:38Z Abstract ISAV is the causative agent of the infectious salmon anaemia (ISA), a disease listed by the OIE that has caused important economic losses to the Atlantic salmon ( Salmo salar ) industry. ISAV variants are identified as pathogenic or non‐pathogenic based on the presence or absence of a deletion in the highly polymorphic region (HPR) of segment 6 (S6). HPRΔ variants (pathogenic) are the only forms of the virus known to grow in cell culture. This is the first report of a HPR0 variant isolated in cell culture. The isolate is, however, atypical as it shows a marker of virulent variants on another segment (S5), which has never been reported for any other HPR0 variants. The significance of this finding remains unclear until more in‐depth work is carried out but does challenge current knowledge. Article in Journal/Newspaper Atlantic salmon Salmo salar Wiley Online Library Journal of Fish Diseases 45 3 479 483 |
institution |
Open Polar |
collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
description |
Abstract ISAV is the causative agent of the infectious salmon anaemia (ISA), a disease listed by the OIE that has caused important economic losses to the Atlantic salmon ( Salmo salar ) industry. ISAV variants are identified as pathogenic or non‐pathogenic based on the presence or absence of a deletion in the highly polymorphic region (HPR) of segment 6 (S6). HPRΔ variants (pathogenic) are the only forms of the virus known to grow in cell culture. This is the first report of a HPR0 variant isolated in cell culture. The isolate is, however, atypical as it shows a marker of virulent variants on another segment (S5), which has never been reported for any other HPR0 variants. The significance of this finding remains unclear until more in‐depth work is carried out but does challenge current knowledge. |
author2 |
Fisheries and Oceans Canada |
format |
Article in Journal/Newspaper |
author |
Ditlecadet, D. Gautreau, C. Boston, L. Liston, R. Johnsen, E. Gagné, N. |
spellingShingle |
Ditlecadet, D. Gautreau, C. Boston, L. Liston, R. Johnsen, E. Gagné, N. First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
author_facet |
Ditlecadet, D. Gautreau, C. Boston, L. Liston, R. Johnsen, E. Gagné, N. |
author_sort |
Ditlecadet, D. |
title |
First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
title_short |
First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
title_full |
First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
title_fullStr |
First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
title_full_unstemmed |
First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
title_sort |
first report of successful isolation of a hpr0‐like variant of the infectious salmon anaemia virus (isav) using cell culture |
publisher |
Wiley |
publishDate |
2021 |
url |
http://dx.doi.org/10.1111/jfd.13556 https://onlinelibrary.wiley.com/doi/pdf/10.1111/jfd.13556 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/jfd.13556 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Journal of Fish Diseases volume 45, issue 3, page 479-483 ISSN 0140-7775 1365-2761 |
op_rights |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
op_doi |
https://doi.org/10.1111/jfd.13556 |
container_title |
Journal of Fish Diseases |
container_volume |
45 |
container_issue |
3 |
container_start_page |
479 |
op_container_end_page |
483 |
_version_ |
1810432574017765376 |