The interaction between temperature and dose on the efficacy and biochemical response of Atlantic salmon to hydrogen peroxide treatment for amoebic gill disease
Abstract Hydrogen peroxide (H 2 O 2 ) is a commonly used treatment for a range of parasitic diseases of marine finfish, including amoebic gill disease (AGD). While this treatment is partially effective at reducing parasite load, H 2 O 2 can have detrimental effects on the host under certain conditio...
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crwiley:10.1111/jfd.13110 2024-09-15T17:56:28+00:00 The interaction between temperature and dose on the efficacy and biochemical response of Atlantic salmon to hydrogen peroxide treatment for amoebic gill disease Wynne, James W. Stratford, Chris Slinger, Joel Samsing, Francisca Rigby, Megan McCulloch, Russell Quezada‐Rodriguez, Petra Taylor, Richard S. Commonwealth Scientific and Industrial Research Organisation 2019 http://dx.doi.org/10.1111/jfd.13110 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjfd.13110 https://onlinelibrary.wiley.com/doi/pdf/10.1111/jfd.13110 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/jfd.13110 en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Journal of Fish Diseases volume 43, issue 1, page 39-48 ISSN 0140-7775 1365-2761 journal-article 2019 crwiley https://doi.org/10.1111/jfd.13110 2024-08-20T04:16:55Z Abstract Hydrogen peroxide (H 2 O 2 ) is a commonly used treatment for a range of parasitic diseases of marine finfish, including amoebic gill disease (AGD). While this treatment is partially effective at reducing parasite load, H 2 O 2 can have detrimental effects on the host under certain conditions. Treatment temperature and dose concentration are two factors that are known to influence the toxicity of H 2 O 2 however, their impact on the outcome of AGD treatment remains unclear. Here, we investigated the effects of treatment temperature (8, 12 or 16°C) and dose concentration (750, 1,000, 1,250 mg/L) on the efficacy of H 2 O 2 to treat AGD. We demonstrated that a 20‐min bath treatment of H 2 O 2 at all doses reduced both parasite load and gross gill score significantly. Parasite load and gross gill score were lowest in the 1,000 mg/L treatment performed at 12°C. At the high dose and temperature combinations, H 2 O 2 caused moderate gill damage and a significant increase in the plasma concentration of electrolytes (sodium, chloride and potassium). Taken together, our study demonstrates that higher H 2 O 2 treatment temperatures can adversely affect the host and do not improve the effectiveness of the treatment. Article in Journal/Newspaper Atlantic salmon Wiley Online Library Journal of Fish Diseases 43 1 39 48 |
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Wiley Online Library |
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crwiley |
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English |
description |
Abstract Hydrogen peroxide (H 2 O 2 ) is a commonly used treatment for a range of parasitic diseases of marine finfish, including amoebic gill disease (AGD). While this treatment is partially effective at reducing parasite load, H 2 O 2 can have detrimental effects on the host under certain conditions. Treatment temperature and dose concentration are two factors that are known to influence the toxicity of H 2 O 2 however, their impact on the outcome of AGD treatment remains unclear. Here, we investigated the effects of treatment temperature (8, 12 or 16°C) and dose concentration (750, 1,000, 1,250 mg/L) on the efficacy of H 2 O 2 to treat AGD. We demonstrated that a 20‐min bath treatment of H 2 O 2 at all doses reduced both parasite load and gross gill score significantly. Parasite load and gross gill score were lowest in the 1,000 mg/L treatment performed at 12°C. At the high dose and temperature combinations, H 2 O 2 caused moderate gill damage and a significant increase in the plasma concentration of electrolytes (sodium, chloride and potassium). Taken together, our study demonstrates that higher H 2 O 2 treatment temperatures can adversely affect the host and do not improve the effectiveness of the treatment. |
author2 |
Commonwealth Scientific and Industrial Research Organisation |
format |
Article in Journal/Newspaper |
author |
Wynne, James W. Stratford, Chris Slinger, Joel Samsing, Francisca Rigby, Megan McCulloch, Russell Quezada‐Rodriguez, Petra Taylor, Richard S. |
spellingShingle |
Wynne, James W. Stratford, Chris Slinger, Joel Samsing, Francisca Rigby, Megan McCulloch, Russell Quezada‐Rodriguez, Petra Taylor, Richard S. The interaction between temperature and dose on the efficacy and biochemical response of Atlantic salmon to hydrogen peroxide treatment for amoebic gill disease |
author_facet |
Wynne, James W. Stratford, Chris Slinger, Joel Samsing, Francisca Rigby, Megan McCulloch, Russell Quezada‐Rodriguez, Petra Taylor, Richard S. |
author_sort |
Wynne, James W. |
title |
The interaction between temperature and dose on the efficacy and biochemical response of Atlantic salmon to hydrogen peroxide treatment for amoebic gill disease |
title_short |
The interaction between temperature and dose on the efficacy and biochemical response of Atlantic salmon to hydrogen peroxide treatment for amoebic gill disease |
title_full |
The interaction between temperature and dose on the efficacy and biochemical response of Atlantic salmon to hydrogen peroxide treatment for amoebic gill disease |
title_fullStr |
The interaction between temperature and dose on the efficacy and biochemical response of Atlantic salmon to hydrogen peroxide treatment for amoebic gill disease |
title_full_unstemmed |
The interaction between temperature and dose on the efficacy and biochemical response of Atlantic salmon to hydrogen peroxide treatment for amoebic gill disease |
title_sort |
interaction between temperature and dose on the efficacy and biochemical response of atlantic salmon to hydrogen peroxide treatment for amoebic gill disease |
publisher |
Wiley |
publishDate |
2019 |
url |
http://dx.doi.org/10.1111/jfd.13110 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjfd.13110 https://onlinelibrary.wiley.com/doi/pdf/10.1111/jfd.13110 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/jfd.13110 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
Journal of Fish Diseases volume 43, issue 1, page 39-48 ISSN 0140-7775 1365-2761 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/jfd.13110 |
container_title |
Journal of Fish Diseases |
container_volume |
43 |
container_issue |
1 |
container_start_page |
39 |
op_container_end_page |
48 |
_version_ |
1810432671443058688 |