Seroprevalence of Toxoplasma gondii Among Nunavik Inuit (Canada)
Summary As a result of their intimate contact with the land and their nutritional habits, the Inuit of Nunavik are considered to be at risk from zoonotic infections. To better understand the risk factors for Toxoplasma gondii infection, a serosurvey was conducted in Nunavik, Québec, in September 200...
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crwiley:10.1111/j.1863-2378.2008.01177.x 2024-03-31T07:53:12+00:00 Seroprevalence of Toxoplasma gondii Among Nunavik Inuit (Canada) Messier, V. Lévesque, B. Proulx, J.‐F. Rochette, L. Libman, M. D. Ward, B. J. Serhir, B. Couillard, M. Ogden, N. H. Dewailly, É. Hubert, B. Déry, S. Barthe, C. Murphy, D. Dixon, B. 2009 http://dx.doi.org/10.1111/j.1863-2378.2008.01177.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1863-2378.2008.01177.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1863-2378.2008.01177.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Zoonoses and Public Health volume 56, issue 4, page 188-197 ISSN 1863-1959 1863-2378 Infectious Diseases Public Health, Environmental and Occupational Health General Veterinary General Immunology and Microbiology Epidemiology journal-article 2009 crwiley https://doi.org/10.1111/j.1863-2378.2008.01177.x 2024-03-05T06:04:16Z Summary As a result of their intimate contact with the land and their nutritional habits, the Inuit of Nunavik are considered to be at risk from zoonotic infections. To better understand the risk factors for Toxoplasma gondii infection, a serosurvey was conducted in Nunavik, Québec, in September 2004. A representative sample of the Inuit adult population of Nunavik participated in this cross‐sectional study ( n = 917). Antibodies (IgG) against T. gondii were detected by immunoassay. Information on sociodemographic characteristics, traditional activities, domestic environment and nutrition was gathered by questionnaire and explored as variables explanatory of seropositive results. Associations found to be statistically significant in univariate analyses were assessed by multivariable logistic regression to control for confounding factors. Almost two thirds (59.8%) of the Inuit of Nunavik were found to be seropositive for T. gondii . In multivariate analyses, risk factors for seropositivity were: increasing age, gender (women > men), lower level of education, consumption of potentially contaminated water (determined by an index of risk from waterborne infections), frequent cleaning of water reservoirs, and consumption of seal meat and feathered game. There was some variation in seroprevalence between the Ungava Bay coast (52.3%) and the Hudson Bay coast (65.6%), the two main regions of Nunavik, but this variation was not significant in the multivariable logistic regression model. This cross‐sectional study demonstrated high T. gondii seroprevalence in the Inuit population and revealed that age, gender, schooling and community of residence all influence serostatus in this population. Variables related to drinking water and food choices may also influence the risk of infection. These results raise important questions about T. gondii transmission in Nunavik including possible links between terrestrial and marine cycles. Article in Journal/Newspaper Hudson Bay inuit Ungava Bay Nunavik Wiley Online Library Canada Hudson Hudson Bay Nunavik Ungava Bay ENVELOPE(-67.489,-67.489,59.498,59.498) Zoonoses and Public Health 56 4 188 197 |
institution |
Open Polar |
collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
topic |
Infectious Diseases Public Health, Environmental and Occupational Health General Veterinary General Immunology and Microbiology Epidemiology |
spellingShingle |
Infectious Diseases Public Health, Environmental and Occupational Health General Veterinary General Immunology and Microbiology Epidemiology Messier, V. Lévesque, B. Proulx, J.‐F. Rochette, L. Libman, M. D. Ward, B. J. Serhir, B. Couillard, M. Ogden, N. H. Dewailly, É. Hubert, B. Déry, S. Barthe, C. Murphy, D. Dixon, B. Seroprevalence of Toxoplasma gondii Among Nunavik Inuit (Canada) |
topic_facet |
Infectious Diseases Public Health, Environmental and Occupational Health General Veterinary General Immunology and Microbiology Epidemiology |
description |
Summary As a result of their intimate contact with the land and their nutritional habits, the Inuit of Nunavik are considered to be at risk from zoonotic infections. To better understand the risk factors for Toxoplasma gondii infection, a serosurvey was conducted in Nunavik, Québec, in September 2004. A representative sample of the Inuit adult population of Nunavik participated in this cross‐sectional study ( n = 917). Antibodies (IgG) against T. gondii were detected by immunoassay. Information on sociodemographic characteristics, traditional activities, domestic environment and nutrition was gathered by questionnaire and explored as variables explanatory of seropositive results. Associations found to be statistically significant in univariate analyses were assessed by multivariable logistic regression to control for confounding factors. Almost two thirds (59.8%) of the Inuit of Nunavik were found to be seropositive for T. gondii . In multivariate analyses, risk factors for seropositivity were: increasing age, gender (women > men), lower level of education, consumption of potentially contaminated water (determined by an index of risk from waterborne infections), frequent cleaning of water reservoirs, and consumption of seal meat and feathered game. There was some variation in seroprevalence between the Ungava Bay coast (52.3%) and the Hudson Bay coast (65.6%), the two main regions of Nunavik, but this variation was not significant in the multivariable logistic regression model. This cross‐sectional study demonstrated high T. gondii seroprevalence in the Inuit population and revealed that age, gender, schooling and community of residence all influence serostatus in this population. Variables related to drinking water and food choices may also influence the risk of infection. These results raise important questions about T. gondii transmission in Nunavik including possible links between terrestrial and marine cycles. |
format |
Article in Journal/Newspaper |
author |
Messier, V. Lévesque, B. Proulx, J.‐F. Rochette, L. Libman, M. D. Ward, B. J. Serhir, B. Couillard, M. Ogden, N. H. Dewailly, É. Hubert, B. Déry, S. Barthe, C. Murphy, D. Dixon, B. |
author_facet |
Messier, V. Lévesque, B. Proulx, J.‐F. Rochette, L. Libman, M. D. Ward, B. J. Serhir, B. Couillard, M. Ogden, N. H. Dewailly, É. Hubert, B. Déry, S. Barthe, C. Murphy, D. Dixon, B. |
author_sort |
Messier, V. |
title |
Seroprevalence of Toxoplasma gondii Among Nunavik Inuit (Canada) |
title_short |
Seroprevalence of Toxoplasma gondii Among Nunavik Inuit (Canada) |
title_full |
Seroprevalence of Toxoplasma gondii Among Nunavik Inuit (Canada) |
title_fullStr |
Seroprevalence of Toxoplasma gondii Among Nunavik Inuit (Canada) |
title_full_unstemmed |
Seroprevalence of Toxoplasma gondii Among Nunavik Inuit (Canada) |
title_sort |
seroprevalence of toxoplasma gondii among nunavik inuit (canada) |
publisher |
Wiley |
publishDate |
2009 |
url |
http://dx.doi.org/10.1111/j.1863-2378.2008.01177.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1863-2378.2008.01177.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1863-2378.2008.01177.x |
long_lat |
ENVELOPE(-67.489,-67.489,59.498,59.498) |
geographic |
Canada Hudson Hudson Bay Nunavik Ungava Bay |
geographic_facet |
Canada Hudson Hudson Bay Nunavik Ungava Bay |
genre |
Hudson Bay inuit Ungava Bay Nunavik |
genre_facet |
Hudson Bay inuit Ungava Bay Nunavik |
op_source |
Zoonoses and Public Health volume 56, issue 4, page 188-197 ISSN 1863-1959 1863-2378 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1863-2378.2008.01177.x |
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Zoonoses and Public Health |
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56 |
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4 |
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188 |
op_container_end_page |
197 |
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