GLUCOSE KINETICS IN NEONATAL ELEPHANT SEALS DURING POSTWEANING APHAGIA
A bstract Northern elephant seal ( Mirounga angustirostris )pups undergo extended periods of terrestrial aphagia after weaning and exhibit a paradoxical fasting hyperglycemia. To investigate the details of glucose metabolism during this period, reversible and irreversible radiotracers were used to d...
Published in: | Marine Mammal Science |
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Wiley
1989
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crwiley:10.1111/j.1748-7692.1989.tb00326.x 2023-12-03T10:22:05+01:00 GLUCOSE KINETICS IN NEONATAL ELEPHANT SEALS DURING POSTWEANING APHAGIA Keith, Edward O. Ortiz, Charles L. 1989 http://dx.doi.org/10.1111/j.1748-7692.1989.tb00326.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1748-7692.1989.tb00326.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1748-7692.1989.tb00326.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Marine Mammal Science volume 5, issue 2, page 99-115 ISSN 0824-0469 1748-7692 Aquatic Science Ecology, Evolution, Behavior and Systematics journal-article 1989 crwiley https://doi.org/10.1111/j.1748-7692.1989.tb00326.x 2023-11-09T14:07:25Z A bstract Northern elephant seal ( Mirounga angustirostris )pups undergo extended periods of terrestrial aphagia after weaning and exhibit a paradoxical fasting hyperglycemia. To investigate the details of glucose metabolism during this period, reversible and irreversible radiotracers were used to determine the body mass of glucose, and rates of glucose turnover, recycling, and oxidation in fasting seal pups. A typical 75 kg pup has a glucose mass of about 4.5 g (60 mg/kg), and a blood glucose concentration of about 174 mg/dl. Blood glucose removal rate was about 30 grams per day (17 mg/kg · h ‐1 ), but less than 2.5% of this glucose was oxidized, contributing less than 1% of the total metabolic rate. About 20% of the glucose pool was removed from the blood per hour, yielding a turnover time in the vascular space of about five hours. Most glucose removed from the blood was returned to the blood by recycling. Such recycling may contribute to mechanisms which prolong survival during fasting, such as high rates of triacyclglycerol turnover, synthesis of new protein pools, low ketone levels, and the Cori cycle which is important during diving. Article in Journal/Newspaper Elephant Seal Elephant Seals Wiley Online Library (via Crossref) Marine Mammal Science 5 2 99 115 |
institution |
Open Polar |
collection |
Wiley Online Library (via Crossref) |
op_collection_id |
crwiley |
language |
English |
topic |
Aquatic Science Ecology, Evolution, Behavior and Systematics |
spellingShingle |
Aquatic Science Ecology, Evolution, Behavior and Systematics Keith, Edward O. Ortiz, Charles L. GLUCOSE KINETICS IN NEONATAL ELEPHANT SEALS DURING POSTWEANING APHAGIA |
topic_facet |
Aquatic Science Ecology, Evolution, Behavior and Systematics |
description |
A bstract Northern elephant seal ( Mirounga angustirostris )pups undergo extended periods of terrestrial aphagia after weaning and exhibit a paradoxical fasting hyperglycemia. To investigate the details of glucose metabolism during this period, reversible and irreversible radiotracers were used to determine the body mass of glucose, and rates of glucose turnover, recycling, and oxidation in fasting seal pups. A typical 75 kg pup has a glucose mass of about 4.5 g (60 mg/kg), and a blood glucose concentration of about 174 mg/dl. Blood glucose removal rate was about 30 grams per day (17 mg/kg · h ‐1 ), but less than 2.5% of this glucose was oxidized, contributing less than 1% of the total metabolic rate. About 20% of the glucose pool was removed from the blood per hour, yielding a turnover time in the vascular space of about five hours. Most glucose removed from the blood was returned to the blood by recycling. Such recycling may contribute to mechanisms which prolong survival during fasting, such as high rates of triacyclglycerol turnover, synthesis of new protein pools, low ketone levels, and the Cori cycle which is important during diving. |
format |
Article in Journal/Newspaper |
author |
Keith, Edward O. Ortiz, Charles L. |
author_facet |
Keith, Edward O. Ortiz, Charles L. |
author_sort |
Keith, Edward O. |
title |
GLUCOSE KINETICS IN NEONATAL ELEPHANT SEALS DURING POSTWEANING APHAGIA |
title_short |
GLUCOSE KINETICS IN NEONATAL ELEPHANT SEALS DURING POSTWEANING APHAGIA |
title_full |
GLUCOSE KINETICS IN NEONATAL ELEPHANT SEALS DURING POSTWEANING APHAGIA |
title_fullStr |
GLUCOSE KINETICS IN NEONATAL ELEPHANT SEALS DURING POSTWEANING APHAGIA |
title_full_unstemmed |
GLUCOSE KINETICS IN NEONATAL ELEPHANT SEALS DURING POSTWEANING APHAGIA |
title_sort |
glucose kinetics in neonatal elephant seals during postweaning aphagia |
publisher |
Wiley |
publishDate |
1989 |
url |
http://dx.doi.org/10.1111/j.1748-7692.1989.tb00326.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1748-7692.1989.tb00326.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1748-7692.1989.tb00326.x |
genre |
Elephant Seal Elephant Seals |
genre_facet |
Elephant Seal Elephant Seals |
op_source |
Marine Mammal Science volume 5, issue 2, page 99-115 ISSN 0824-0469 1748-7692 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1748-7692.1989.tb00326.x |
container_title |
Marine Mammal Science |
container_volume |
5 |
container_issue |
2 |
container_start_page |
99 |
op_container_end_page |
115 |
_version_ |
1784269906591612928 |