Haematological, ocular and skeletal abnormalities in a samoyed family

• Published in: Journal of Small Animal Practice
• Main Authors: Aroch, I., Ofri, R., Aizenberg, I.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 1996
• Subjects: Small Animals; samoyed*
• Online Access: http://dx.doi.org/10.1111/j.1748-5827.1996.tb02403.x; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1748-5827.1996.tb02403.x; https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1748-5827.1996.tb02403.x

ABSTRACT Haematological, ocular and skeletal abnormalities were documented in a samoyed male and its five offspring. Haematological abnormalities, found in repeated tests in all the dogs, included marked eosinophilia, eosinophilic bands and absence of Barr bodies. Two of the dogs had bilateral buphthalmia, retinal detachments and other ocular abnormalities. Three of the dogs had skeletal abnormalities including chondrodysplasia (dwarfism) and brachygnathia (undershot jaw). A similar combination of inherited skeletal and ocular disorders, without the haematological abnormalities, has been described in samoyeds. Acquired causes for the haematological findings, which are similar to the inherited Pelger‐Huët anomaly described in several species, have been eliminated. Eosinophilic bands and scarcity of Barr bodies could be a marker, or a previously unreported manifestation, of an inherited disorder in samoyeds.