Serum Concentrations of Vitamin D Metabolites in Exclusively Breast‐Fed Infants at 70° North
ABSTRACT. The effect of prolonged breast‐feeding on the serum concentrations of vitamin D metabolites, calcium, phosphate, and alkaline phosphatase was studied longitudinally in 7 infants from Northern Norway. They were exclusively breast‐fed for a median of 71/2 months. Three of the mothers were su...
Published in: | Acta Paediatrica |
---|---|
Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
1984
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1111/j.1651-2227.1984.tb09893.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1651-2227.1984.tb09893.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1651-2227.1984.tb09893.x |
id |
crwiley:10.1111/j.1651-2227.1984.tb09893.x |
---|---|
record_format |
openpolar |
spelling |
crwiley:10.1111/j.1651-2227.1984.tb09893.x 2023-12-03T10:27:51+01:00 Serum Concentrations of Vitamin D Metabolites in Exclusively Breast‐Fed Infants at 70° North MARKESTAD, T. KOLMANNSKOG, S. ARNTZEN, E. TOFTEGAARD, L. HANEBERG, B. AKSNES, L. 1984 http://dx.doi.org/10.1111/j.1651-2227.1984.tb09893.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1651-2227.1984.tb09893.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1651-2227.1984.tb09893.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Acta Paediatrica volume 73, issue 1, page 29-32 ISSN 0803-5253 1651-2227 General Medicine Pediatrics, Perinatology and Child Health journal-article 1984 crwiley https://doi.org/10.1111/j.1651-2227.1984.tb09893.x 2023-11-09T14:27:37Z ABSTRACT. The effect of prolonged breast‐feeding on the serum concentrations of vitamin D metabolites, calcium, phosphate, and alkaline phosphatase was studied longitudinally in 7 infants from Northern Norway. They were exclusively breast‐fed for a median of 71/2 months. Three of the mothers were supplemented with vitamin D throughout lactation. All but one of the infants had 25‐hydroxyvitamin D (25‐OHD) levels in the rachitic range (< 20 nmol/l) on at least one occasion. Vitamin D supplementation of the mother had no apparent effect on the infants' 25‐OHD levels, but the values increased during summer. The infant who had the lowest 25‐OHD levels also had decreased 1,25‐dihydroxyvitamin D (1,25‐(OH) 2 D) concentrations, while the others maintained l,25‐(OH) 2 D levels within normal limits. 24,25‐(OH) 2 D concentrations were undetectable when the 25‐OHD levels were below 35 nmol/l, but the two metabolites were closely correlated for higher values of 25‐OHD. Low 25‐OHD levels were associated with decreased phosphate concentrations at 6 months. The calcium levels were normal throughout the study period of one year, as were all but two of the alkaline phospatase values. Although none of the infants had clinical or biochemical evidence of rickets, the results suggest that the vitamin D supply from human milk is inadequate, and that routine vitamin D supplementation is advisable for breast‐fed infants who are deprived of sunlight exposure. Article in Journal/Newspaper Northern Norway Wiley Online Library (via Crossref) Norway Acta Paediatrica 73 1 29 32 |
institution |
Open Polar |
collection |
Wiley Online Library (via Crossref) |
op_collection_id |
crwiley |
language |
English |
topic |
General Medicine Pediatrics, Perinatology and Child Health |
spellingShingle |
General Medicine Pediatrics, Perinatology and Child Health MARKESTAD, T. KOLMANNSKOG, S. ARNTZEN, E. TOFTEGAARD, L. HANEBERG, B. AKSNES, L. Serum Concentrations of Vitamin D Metabolites in Exclusively Breast‐Fed Infants at 70° North |
topic_facet |
General Medicine Pediatrics, Perinatology and Child Health |
description |
ABSTRACT. The effect of prolonged breast‐feeding on the serum concentrations of vitamin D metabolites, calcium, phosphate, and alkaline phosphatase was studied longitudinally in 7 infants from Northern Norway. They were exclusively breast‐fed for a median of 71/2 months. Three of the mothers were supplemented with vitamin D throughout lactation. All but one of the infants had 25‐hydroxyvitamin D (25‐OHD) levels in the rachitic range (< 20 nmol/l) on at least one occasion. Vitamin D supplementation of the mother had no apparent effect on the infants' 25‐OHD levels, but the values increased during summer. The infant who had the lowest 25‐OHD levels also had decreased 1,25‐dihydroxyvitamin D (1,25‐(OH) 2 D) concentrations, while the others maintained l,25‐(OH) 2 D levels within normal limits. 24,25‐(OH) 2 D concentrations were undetectable when the 25‐OHD levels were below 35 nmol/l, but the two metabolites were closely correlated for higher values of 25‐OHD. Low 25‐OHD levels were associated with decreased phosphate concentrations at 6 months. The calcium levels were normal throughout the study period of one year, as were all but two of the alkaline phospatase values. Although none of the infants had clinical or biochemical evidence of rickets, the results suggest that the vitamin D supply from human milk is inadequate, and that routine vitamin D supplementation is advisable for breast‐fed infants who are deprived of sunlight exposure. |
format |
Article in Journal/Newspaper |
author |
MARKESTAD, T. KOLMANNSKOG, S. ARNTZEN, E. TOFTEGAARD, L. HANEBERG, B. AKSNES, L. |
author_facet |
MARKESTAD, T. KOLMANNSKOG, S. ARNTZEN, E. TOFTEGAARD, L. HANEBERG, B. AKSNES, L. |
author_sort |
MARKESTAD, T. |
title |
Serum Concentrations of Vitamin D Metabolites in Exclusively Breast‐Fed Infants at 70° North |
title_short |
Serum Concentrations of Vitamin D Metabolites in Exclusively Breast‐Fed Infants at 70° North |
title_full |
Serum Concentrations of Vitamin D Metabolites in Exclusively Breast‐Fed Infants at 70° North |
title_fullStr |
Serum Concentrations of Vitamin D Metabolites in Exclusively Breast‐Fed Infants at 70° North |
title_full_unstemmed |
Serum Concentrations of Vitamin D Metabolites in Exclusively Breast‐Fed Infants at 70° North |
title_sort |
serum concentrations of vitamin d metabolites in exclusively breast‐fed infants at 70° north |
publisher |
Wiley |
publishDate |
1984 |
url |
http://dx.doi.org/10.1111/j.1651-2227.1984.tb09893.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1651-2227.1984.tb09893.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1651-2227.1984.tb09893.x |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Northern Norway |
genre_facet |
Northern Norway |
op_source |
Acta Paediatrica volume 73, issue 1, page 29-32 ISSN 0803-5253 1651-2227 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1651-2227.1984.tb09893.x |
container_title |
Acta Paediatrica |
container_volume |
73 |
container_issue |
1 |
container_start_page |
29 |
op_container_end_page |
32 |
_version_ |
1784277770635837440 |