THE INCIDENCE AND GENETICS OF METACHROMATIC LEUCODYSTROPHY IN NORTHERN SWEDEN
Summary The purpose of this study was to investigate the incidence and genetics of metachromatic leuco‐dystrophy (MLD). A series of 13 cases of late infantile MLD and 2 cases of juvenile MLD was collected from the northern part of Sweden and studied together with their relatives. The series was cons...
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crwiley:10.1111/j.1651-2227.1971.tb06994.x 2024-03-24T09:04:09+00:00 THE INCIDENCE AND GENETICS OF METACHROMATIC LEUCODYSTROPHY IN NORTHERN SWEDEN GUSTAVSON, K.‐H. HAGBERG, BENGT 1971 http://dx.doi.org/10.1111/j.1651-2227.1971.tb06994.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1651-2227.1971.tb06994.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1651-2227.1971.tb06994.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor Acta Paediatrica volume 60, issue 5, page 585-590 ISSN 0803-5253 1651-2227 General Medicine Pediatrics, Perinatology and Child Health journal-article 1971 crwiley https://doi.org/10.1111/j.1651-2227.1971.tb06994.x 2024-02-28T02:13:57Z Summary The purpose of this study was to investigate the incidence and genetics of metachromatic leuco‐dystrophy (MLD). A series of 13 cases of late infantile MLD and 2 cases of juvenile MLD was collected from the northern part of Sweden and studied together with their relatives. The series was considered to be adequately representative of the true occurrence of MLD during the period 1955–1965. The incidence rate for late infantile MLD was estimated to be about 1 per 40 000. The MLD patients were highly concentrated to the south‐west part of Norrland. From the family analysis it was concluded that late infantile MLD is most probably transmitted by an autosomal recessive gene. Article in Journal/Newspaper Northern Sweden Wiley Online Library Acta Paediatrica 60 5 585 590 |
institution |
Open Polar |
collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
topic |
General Medicine Pediatrics, Perinatology and Child Health |
spellingShingle |
General Medicine Pediatrics, Perinatology and Child Health GUSTAVSON, K.‐H. HAGBERG, BENGT THE INCIDENCE AND GENETICS OF METACHROMATIC LEUCODYSTROPHY IN NORTHERN SWEDEN |
topic_facet |
General Medicine Pediatrics, Perinatology and Child Health |
description |
Summary The purpose of this study was to investigate the incidence and genetics of metachromatic leuco‐dystrophy (MLD). A series of 13 cases of late infantile MLD and 2 cases of juvenile MLD was collected from the northern part of Sweden and studied together with their relatives. The series was considered to be adequately representative of the true occurrence of MLD during the period 1955–1965. The incidence rate for late infantile MLD was estimated to be about 1 per 40 000. The MLD patients were highly concentrated to the south‐west part of Norrland. From the family analysis it was concluded that late infantile MLD is most probably transmitted by an autosomal recessive gene. |
format |
Article in Journal/Newspaper |
author |
GUSTAVSON, K.‐H. HAGBERG, BENGT |
author_facet |
GUSTAVSON, K.‐H. HAGBERG, BENGT |
author_sort |
GUSTAVSON, K.‐H. |
title |
THE INCIDENCE AND GENETICS OF METACHROMATIC LEUCODYSTROPHY IN NORTHERN SWEDEN |
title_short |
THE INCIDENCE AND GENETICS OF METACHROMATIC LEUCODYSTROPHY IN NORTHERN SWEDEN |
title_full |
THE INCIDENCE AND GENETICS OF METACHROMATIC LEUCODYSTROPHY IN NORTHERN SWEDEN |
title_fullStr |
THE INCIDENCE AND GENETICS OF METACHROMATIC LEUCODYSTROPHY IN NORTHERN SWEDEN |
title_full_unstemmed |
THE INCIDENCE AND GENETICS OF METACHROMATIC LEUCODYSTROPHY IN NORTHERN SWEDEN |
title_sort |
incidence and genetics of metachromatic leucodystrophy in northern sweden |
publisher |
Wiley |
publishDate |
1971 |
url |
http://dx.doi.org/10.1111/j.1651-2227.1971.tb06994.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1651-2227.1971.tb06994.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1651-2227.1971.tb06994.x |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_source |
Acta Paediatrica volume 60, issue 5, page 585-590 ISSN 0803-5253 1651-2227 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1651-2227.1971.tb06994.x |
container_title |
Acta Paediatrica |
container_volume |
60 |
container_issue |
5 |
container_start_page |
585 |
op_container_end_page |
590 |
_version_ |
1794405207568809984 |