Mutations in gastrointestinal stromal tumors – a population‐based study from Northern Norway

• Published in: APMIS
• Main Authors: STEIGEN, SONJA E., EIDE, TOR J., WASAG, BARTOSZ, LASOTA, JERZY, MIETTINEN, MARKKU
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 2007
• Subjects: Gist; Norway; Northern Norway
• Online Access: http://dx.doi.org/10.1111/j.1600-0463.2007.apm_587.x; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1600-0463.2007.apm_587.x; https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1600-0463.2007.apm_587.x

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. This tumor typically expresses KIT, and has KIT or PDGFRA activating mutation. In this study we evaluated 89 GISTs diagnosed in Northern Norway during a 30‐year period. KIT exons 8, 9, 11, 13, a...